Publications of Institute of Radiopharmaceutical Cancer Research

Involved institute: Institute of Radiopharmaceutical Cancer Research
Year of Controlling (approved, published, possibly Online First)
Articles ref. in Journals
"Online First" included
Approved and published publications
Only approved publications

1324 Publications

2023

Palbociclib impairs the proliferative capacity of activated T cells while retaining their cytotoxic efficacy

Arndt, C.; Tunger, A.; Wehner, R.; Rothe, R.; Kourtellari, E.; et al. (16 authors)


Reproducibility of 3T APT-CEST in healthy volunteers and brain glioma patients

Wamelink, I. J. H. G.; Kuijer, J. P. A.; Padrela, B. E.; Zhang, Y.; Barkhof, F.; et al. (9 authors)

  • Open Access Logo Journal of Magnetic Resonance Imaging 57(2023)1, 206-215
    Online First (2022) DOI: 10.1002/jmri.28239

Significance of pulmonary endothelial injury and the role of cyclooxygenase-2 and prostanoid signaling

Nickl, R.; Hauser, S.; Pietzsch, J.; Richter, T.


2022

Clinical Significance of Tumor-Infiltrating Conventional and Plasmacytoid Dendritic Cells in Pancreatic Ductal Adenocarcinoma

Plesca, I.; Benešová, I.; Beer, C.; Sommer, U.; Müller, L.; et al. (15 authors)


Interfacial dynamics of adsorption layers as support of biomedical research and diagnostics

Santini, E.; Nepita, I.; Bykov, A. G.; Ravera, F.; Liggieri, L.; et al. (9 authors)


Pickering foams and parameters influencing their characteristics

Amani, P.; Miller, R.; Javadi, A.; Firouzi, M.


Unfolded Lipase at Interfaces Studied via Interfacial Dilational Rheology: The Impact of Urea

Dowlati, S.; Javadi, A.; Miller, R.; Eckert, K.; Kraume, M.


Synthesis and preclinical evaluation of rhenium and technetium-99m “4 + 1” mixed-ligand complexes bearing quinazoline derivatives as potential EGFR imaging agents

Kiritsis, C.; Shegani, A.; Makrypidi, K.; Roupa, I.; Lazopoulos, A.; et al. (12 authors)


Induction of pulmonary HLA-G expression by SARS-CoV-2 infection

Seliger, B.; Jasinski-Bergner, S.; Masssa, C.; Müller, A.; Biehl, K.; et al. (12 authors)


Towards personalized medicine: one chelator for imaging and therapy with lutetium-177 and actinium-225

Cieslik, P.; Kubeil, M.; Zarschler, K.; Ullrich, M.; Brandt, F.; et al. (12 authors)


Refined Chelator Spacer Moieties Ameliorate the Pharmacokinetics of PSMA-617.

Dos, S. J.; Schäfer, M.; Bauder-Wüst, U.; Beijer, B.; Eder, M.; et al. (14 authors)


Highlight selection of radiochemistry and radiopharmacy developments by editorial board.

Toyohara, J.; Al-Qahtani, M.; Huang, Y.; Cazzola, E.; Todde, S.; et al. (21 authors)


Case report: Incidentally discovered case of pheochromocytoma as a cause of long COVID-19 syndrome

Ziegler, C. G.; Riediger, C.; Gruber, M.; Kunath, C.; Ullrich, M.; et al. (11 authors)


The Chemotype of Chromanones as a Privileged Scaffold for Multineurotarget Anti-Alzheimer Agents

Keuler, T.; Lemke, C.; Elsinghorst, P. W.; Iriepa, I.; Chioua, M.; et al. (14 authors)


A fluorescence anisotropy assay with guanine nucleotides provides access to functional analysis of Gαi1 proteins

Penanian, A.; Sommerfeld, P.; Kasprzyk, R.; Kühl, T.; Binbay, A.; et al. (14 authors)


Efficient Production of the PET radionuclide 133La for Theranostic Purposes in Targeted Alpha Therapy using the 134Ba(p,2n)133La Reaction

Brühlmann, S. A.; Kreller, M.; Pietzsch, H.-J.; Kopka, K.; Mamat, C.; et al. (7 authors)


Exploring nitric oxide (NO)- releasing celecoxib derivatives as modulators of radioresponse in pheochromocytoma cells

Brandt, F.; Ullrich, M.; Seifert, V.; Haase-Kohn, C.; Richter, S.; et al. (8 authors)


Radiosynthesis and preclinical evaluation of an 18F-labeled tri-azolopyridopyrazine-based inhibitor for neuroimaging of the phosphodiesterase 2A (PDE2A)

Wenzel, B.; Fritzsche, S. R.; Toussaint, M.; Briel, D.; Kopka, K.; et al. (8 authors)


Development of Radiotracers for Imaging of the PD-1/PD-L1 Axis

Krutzek, F.; Kopka, K.; Stadlbauer, S.


Development of a neurotensin-derived 68Ga-labeled PET ligand with high in vivo stability for imaging of NTS1 receptor-expressing tumors

Schindler, L.; Moosbauer, J.; Schmidt, D.; Spruss, T.; Grätz, L.; et al. (13 authors)


Fluorination of silyl prosthetic groups by fluorine mediated silyl ether linker cleavage: a concept study with conditions applicable in radiofluorination

Kramer, C. S.; Greiner, L.; Kopka, K.; Schäfer, M.


Electrokinetic Janus micromotors moving on topographically flat chemical patterns

Huang, T.; Misko, V.; Caspari, A.; Synytska, A.; Ibarlucea, B.; et al. (10 authors)


Cyclam with a phosphinate-bis(phosphonate) pendant arm is a bone-targeting carrier of copper radionuclides

Pazderová, L.; Benešová, M.; Havlíčková, J.; Vojtíčková, M.; Kotek, J.; et al. (15 authors)


Sulfated glycosaminoglycans inhibit transglutaminase 2 by stabilizing its closed conformation

Müller, C. D.; Ruiz-Gómez, G.; Cazzonelli, S.; Möller, S.; Wodtke, R.; et al. (12 authors)


Nanochips assisted peptide screening for clinical development of CAR-T cell immunotherapy

Anh Nguyen-Le, T.; Bartsch, T.; Wodtke, R.; Brandt, F.; Arndt, C.; et al. (18 authors)


Long-term excessive dietary phosphate increases arterial blood pressure, activates the renin-angiotensin-aldosterone system, and stimulates sympathetic tone in mice

Latic, N.; Peitzsch, M.; Zupcic, A.; Pietzsch, J.; Erben, R. G.


Impact of sulfated hyaluronan on bone metabolism in diabetic Charcot neuroarthropathy and degenerative arthritis

Schulze, S.; Neuber, C.; Möller, S.; Hempel, U.; Hofbauer, L. C.; et al. (8 authors)


Combining Radiation- with Immunotherapy in Prostate Cancer: Influence of Radiation on T cells

Lindner, D.; Arndt, C.; Loureiro, L. R.; Feldmann, A.; Kegler, A.; et al. (11 authors)


Modulating the pharmacokinetic profile of Actinium-225-labeled macropa-derived radioconjugates by dual targeting of PSMA and albumin

Reissig, F.; Zarschler, K.; Novy, Z.; Petrik, M.; Bendova, K.; et al. (14 authors)


The Open-Access European Prevention of Alzheimer’s Dementia (EPAD) MRI dataset and processing workflow

Lorenzini, L.; Ingala, S.; Wink, A. M.; Kuijer, J. P. A.; Wottschel, V.; et al. (30 authors)


1-(4-Fluorobenzoyl)-9H-carbazole

Laube, M.; König, J.; Köckerling, M.; Knieß, T.


PET Imaging of Cholinergic Neurotransmission in Neurodegenerative Disorders

Tiepolt, S.; Meyer, P. M.; Patt, M.; Deuther-Conrad, W.; Hesse, S.; et al. (7 authors)


Recent technical developments in ASL: A Review of the State of the Art

Hernandez-Garcia, L.; Aramendia, V.; Dai, W.; Bolar, D.; Fernández-Seara, M. A.; et al. (21 authors)


Correlation Between Quantitative PSMA PET Parameters and Clinical Risk Factors in Non-Metastatic Primary Prostate Cancer Patients

Zschaeck, S.; Andela, S. B.; Amthauer, H.; Furth, C.; Rogasch, J. M.; et al. (8 authors)


Switching on Cytotoxicity of Water-Soluble Diiron Organometallics by UV Irradiation

Biancalana, L.; Kubeil, M.; Schoch, S.; Zacchini, S.; Marchetti, F.


Real-Time Monitoring of Blood Parameters in the Intensive Care Unit: State-of-the-Art and Perspectives

Bockholt, R.; Paschke, S.; Heubner, L.; Ibarlucea, B.; Laupp, A.; et al. (13 authors)


Novel radioiodinated and radiofluorinated analogues of FT-2102 for SPECT or PET imaging of mIDH1 mutant tumours

Weber, V.; Arnaud, L.; Dukic-Stefanovic, S.; Wenzel, B.; Roux, V.; et al. (12 authors)


A Beginner’s Guide to Arterial Spin Labeling (ASL) Image Processing

Clement, P.; Petr, J.; Dijsselhof, M. B.; Padrela, B.; Pasternak, M.; et al. (14 authors)


Investigation of Tumor Cells and Receptor-Ligand Simulation Models for the Development of PET Imaging Probes Targeting PSMA and GRPR and a Possible Crosstalk between the Two Receptors

Liolios, C.; Patsis, C.; Lambrinidis, G.; Tzortzini, E.; Roscher, M.; et al. (8 authors)


Investigation of radiotracer metabolic stability in vitro with CYP-overexpressing hepatoma cell lines

Lemm, S.; Köhler, S.; Wodtke, R.; Jung, F.; Küpper, J.-H.; et al. (7 authors)


Local control after locally ablative, image-guided radiotherapy of oligometastases identified by Gallium-68-PSMA-Positron Emission Tomography in castration-sensitive prostate cancer patients (OLI-P)

Hölscher, T.; Baumann, M.; Kotzerke, J.; Zöphel, K.; Paulsen, F.; et al. (13 authors)


Targeting CD10 on B-Cell Leukemia Using the Universal CAR T-Cell Platform (UniCAR)

Mitwasi, N.; Arndt, C.; Loureiro, L. R.; Kegler, A.; Fasslrinner, F.; et al. (11 authors)


Radiopharmazie des vergangenen Jahrzehnts

Steinbach, J.; Kopka, K.


Atherosclerotic risk is associated with cerebral perfusion – a cross-sectional study using arterial spin labelling MRI

Hafdi, M.; Mutsaerts, H. J.; Petr, J.; Richard, E.; van Dalen, J. W.


Introducing micro physiological systems to evaluate new radiopharmaceuticals: First attempts with radiolabeled cetuximab

Sihver, W.; Nitt-Weber, A.-K.; Behrens, S.; Ullrich, M.; Pietzsch, H.-J.; et al. (8 authors)


Development and functional characterization of a versatile radio-/immunotheranostic tool for prostate cancer management

Arndt, C.; Bergmann, R.; Striese, F.; Merkel, K.; Máthé, D.; et al. (21 authors)


Validation of CD98hc as a therapeutic target for a combination of radiation and immunotherapies in head and neck squamous cell carcinoma

Köseer, A. S.; Loureiro, L. R.; Jureczek, J.; Mitwasi, N.; González Soto, K. E.; et al. (14 authors)


Personalized drug testing in human pheochromocytoma/paraganglioma primary cultures

Wang, K.; Schütze, I.; Gulde, S.; Bechmann, N.; Richter, S.; et al. (38 authors)


Application of a fluorescence anisotropy-based assay to quantify transglutaminase 2 activity in cell lysates

Hauser, S.; Sommerfeld, P.; Wodtke, J.; Hauser, C.; Schlitterlau, P.; et al. (9 authors)


Synthesis and characterization of the two enantiomers of a chiral sigma-1 receptor radioligand: (S)-(+)- and (R)-(-)-[18F]FBFP

Wang, T.; Zhang, Y.; Zhang, X.; Chen, L.; Zheng, M.-Q.; et al. (10 authors)


Carboranyl analogues of mefenamic acid and their biological evaluation

Useini, L.; Mojic, M.; Laube, M.; Lönnecke, P.; Dahme, J.; et al. (10 authors)


Dual-Labelling Strategies for Nuclear and Fluorescence Molecular Imaging: Current Status and Future Perspectives

Kubeil, M.; Santana Martinez, I. I.; Bachmann, M.; Kopka, K.; Tuck L., K.; et al. (6 authors)


A New Class of PSMA-617-Based Hybrid Molecules for Preoperative Imaging and Intraoperative Fluorescence Navigation of Prostate Cancer

Eder, A.; Matthias, J.; Schäfer, M.; Schmidt, J.; Steinacker, N.; et al. (11 authors)


Comparison of Image Quality and Spatial Resolution Between 18F, 68Ga and 64Cu Phantom Measurements Using a Digital Biograph Vision PET/CT

Braune, A.; Oehme, L.; Freudenberg, R.; Hofheinz, F.; van den Hoff, J.; et al. (7 authors)


Influences on PET Quantification and Interpretation

Rogasch, J.; Hofheinz, F.; van Heek, L.; Voltin, C.; Boellaard, R.; et al. (6 authors)


Enhanced survival of high-risk medulloblastoma-bearing mice after multimodal treatment with radiotherapy, decitabine, and abacavir

Gringmuth, M.; Walther, J.; Greiser, S.; Toussaint, M.; Schwalm, B.; et al. (9 authors)


Multisite Dopamine Sensing with Femtomolar Resolution Using a CMOS Enabled Aptasensor Chip

Baraban, L.; Seichepine, F.; Sessi, V.; Ibarlucea, B.; Klinghammer, S.; et al. (13 authors)


Strained Ammonium Precursors for Radiofluorinations

Reissig, F.; Mamat, C.


Beyond Active Colloids: From Functional Materials to Microscale Robotics

Simmchen, J.; Baraban, L.; Wang, W.


Amphiphilic Anionic Oligomer-Stabilized Calcium Phosphate Nanoparticles with Prospects in siRNA Delivery via Convection-Enhanced Delivery

Mitrach, F.; Schmid, M.; Toussaint, M.; Dukic-Stefanovic, S.; Deuther-Conrad, W.; et al. (12 authors)


Highlight selection of radiochemistry and radiopharmacy developments by editorial board

Bernardes, E.; Caravan, P.; van Dam, M.; Deuther-Conrad, W.; Ellis, B.; et al. (23 authors)


A pharmacokinetic and metabolism study of the TRPC6 inhibitor SH045 in mice by LC-MS/MS

Chai, X.-N.; Ludwig, F.-A.; Müglitz, A.; Gong, Y.; Schaefer, M.; et al. (7 authors)


Characterization of protein corona formation on nanoparticles via the analysis of dynamic interfacial properties: Bovine serum albumin - silica particle interaction

Shourni, S.; Javadi, A.; Hosseinpour, N.; Bahramian, A.; Raoufi, M.


Experimental techniques to study protein–surfactant interactions: New insights into competitive adsorptions via drop subphase and Interface exchange

Javadi, A.; Dowlati, S.; Shourni, S.; Miller, R.; Kraume, M.; et al. (7 authors)


Development and Biological Evaluation of the First Highly Potent and Specific Benzamide-Based Radiotracer [¹⁸F]BA3 for Imaging of Histone Deacetylases 1 and 2 in Brain

Clauß, O.; Schäker-Hübner, L.; Wenzel, B.; Toussaint, M.; Deuther-Conrad, W.; et al. (13 authors)


11C-Methionine Uptake in the Lactating Human Breast

Michler, E.; Hilliger, S.; Kopka, K.; Kotzerke, J.


EANM Position on the In-House Preparation of Radiopharmaceuticals

Hendrikse, H.; Kiß, O.; Kunikowska, J.; Wadsak, W.; Decristoforo, C.; et al. (6 authors)


Structure-Based Design, Optimization and Development of [18F]LU13, a novel radioligand for CB2R Imaging in the Brain with PET

Gündel, D.; Deuther-Conrad, W.; Ueberham, L.; Kaur, S.; Otikova, E.; et al. (14 authors)


A self-assembled matrix system for cell-bioengineering applications in different dimensions, scales, and geometries

Xu, Y.; Patino Gaillez, M.; Zheng, K.; Voigt, D.; Cui, M.; et al. (16 authors)


ASL-BIDS, the brain imaging data structure extension for arterial spin labeling

Clement, P.; Castellaro, M.; Okell, T. W.; Thomas, D. L.; Vandemaele, P.; et al. (21 authors)


Arterial Spin-Labeling Parameters and Their Associations with Risk Factors, Cerebral Small-Vessel Disease, and Etiologic Subtypes of Cognitive Impairment and Dementia

Gyanwali, B.; Seng Tan, C.; Petr, J.; Tirado Escobosa, L. L.; Vrooman, H.; et al. (8 authors)


Association of arterial spin labeling parameters with cognitive decline, vascular events and mortality in a memory-clinic sample

Gyanwali, B.; Mutsaerts, H. J. M. M.; Seng Tan, C.; Rajab Kaweilh, O.; Petr, J.; et al. (7 authors)


Cerebral perfusion and the risk for cognitive decline and dementia in community dwelling older people

Abdulrahman, H.; Hafdi, M.; Mutsaerts, H. J. M. M.; Nederveen, A. J.; Petr, J.; et al. (8 authors)


A convenient route to new (radio)fluorinated and (radio)iodinated cyclic tyrosine analogues.

Noelia Chao, M.; Chezal, J.-M.; Debiton, E.; Canitrot, D.; Witkowski, T.; et al. (12 authors)


The role of transglutaminase 2 in the radioresistance of melanoma cells

Aepler, J.; Wodtke, J.; Wodtke, R.; Haase-Kohn, C.; Löser, R.; et al. (7 authors)


Therapeutic Potential of Nitric Oxide releasing Selective Estrogen Receptor Modulators (NO-SERMs) in Malignant Melanoma

Bechmann, N.; Calsina, B.; Richter, S.; Pietzsch, J.


Bis(amido)bis(oxinate)diamine ligands for theranostic radiometals

Southcott, L.; Whetter, J. N.; Wharton, L.; Patrick, B. O.; Zarschler, K.; et al. (9 authors)


EANM Guideline on Quality Risk Management for radiopharmaceuticals

Gillings, N.; Hjelstuen, O.; Behe, M.; Decristoforo, C.; Elsinga, P.; et al. (15 authors)


Cyclotrons operated for Nuclear Medicine and Radiopharmacy in the German speaking D-A-CH countries: An update on current status and trends

Zippel, C.; Ermert, J.; Patt, M.; Gildehaus, F. J.; Ross, T. L.; et al. (12 authors)


Automated radiosynthesis of the adenosine A2A receptor-targeting radiotracer [18F]FLUDA

Lai, T. H.; Wenzel, B.; Moldovan, R.-P.; Brust, P.; Kopka, K.; et al. (6 authors)

  • Open Access Logo Journal of Labelled Compounds and Radiopharmaceuticals 65(2022), 162-166
    DOI: 10.1002/jlcr.3970

Quantitation of the A2A adenosine receptor density in the striatum of mice and pigs with [18F]FLUDA by positron emission tomography

Gündel, D.; Toussaint, M.; Lai, T. H.; Deuther-Conrad, W.; Cumming, P.; et al. (10 authors)


Non-invasive assessment of locally overexpressed human adenosine 2A receptors in the heart of transgenic mice

Gündel, D.; Lai, T. H.; Dukic-Stefanovic, S.; Teodoro, R.; Deuther-Conrad, W.; et al. (13 authors)


“Clickable” albumin binders for modulating the tumor uptake of targeted radiopharmaceuticals

Brandt, F.; Ullrich, M.; Laube, M.; Kopka, K.; Bachmann, M.; et al. (10 authors)


Towards Optimized Bioavailability of 99mTc‑Labeled Barbiturates for Non‑invasive Imaging of Matrix Metalloproteinase Activity

Honold, L.; Austrup, M.; Faust, A.; Konken, C.; Schwegmann, K.; et al. (11 authors)


A systematic review on the use of quantitative imaging to detect cancer therapy adverse effects in normal-appearing brain tissue

Petr, J.; Hogeboom, L.; Nikulin, P.; Wiegers, E.; Schroyen, G.; et al. (20 authors)

  • Open Access Logo Magnetic Resonance Materials in Physics, Biology and Medicine 35(2022), 163-186
    Online First (2021) DOI: 10.1007/s10334-021-00985-2

Tumor irradiation in mice with a laser-accelerated proton beam

Kroll, F.; Brack, F.-E.; Bernert, C.; Bock, S.; Bodenstein, E.; et al. (31 authors)


Role of TRPC6 in Kidney Damage after Acute Ischemic Kidney Injury

Zheng, Z.; Tsvetkov, D.; Bartolomaeus, T.; Erdogan, C.; Krügel, U.; et al. (15 authors)


Discovery and development of brain-penetrant 18F-labeled radioligands for neuroimaging of the sigma-2 receptors

Zhang, Y.; Wang, T.; Zhang, X.; Deuther-Conrad, W.; Fu, H.; et al. (10 authors)


Cisplatin - A more Efficient Drug in Combination with Radionuclides?

Reissig, F.; Runge, R.; Naumann, A.; Kotzerke, J.


Overestimation of grey matter atrophy in glioblastoma patients following radio(chemo)therapy

Gommlich, A.; Raschke, F.; Petr, J.; Seidlitz, A.; Jentsch, C.; et al. (12 authors)

  • Open Access Logo Magnetic Resonance Materials in Physics, Biology and Medicine 35(2022), 145-152
    Online First (2021) DOI: 10.1007/s10334-021-00922-3

Preparation of calix[4]arenes for chelation of selected divalent cations

Blumberg, M.; Al-Ameed, K.; Eiselt, E.; Luber, S.; Mamat, C.


Cerebral blood flow of the frontal lobe in untreated children with trigonocephaly vs healthy controls: an arterial spin labeling study

de Planque, C. A.; Petr, J.; Gaillard, L.; Mutsaerts, H. J.; van Veelen, M. L. C.; et al. (8 authors)


CRISPR/Cas9 mediated knockout of cyclooxygenase-2 gene inhibits invasiveness in A2058 melanoma cells

Haase-Kohn, C.; Laube, M.; Donat, C.; Belter, B.; Pietzsch, J.


2021

Enzymatic Hydrolysis of Triglycerides at the Water–Oil Interface Studied via Interfacial Rheology Analysis of Lipase Adsorption Layers

Javadi, A.; Dowlati, S.; Shourni, S.; Rusli, S.; Eckert, K.; et al. (7 authors)


CTAB-Silica nanoparticle complexes - dynamic surface tension measurements and modeling

Javadi, A.; Jafarlou, A.; Eckert, K.; Miller, R.


Prognostic Value of Pretherapeutic Primary Tumour MTV from [18F]FDG PET in Radically Treated Cervical Cancer Patients

Cegla, P.; Hofheinz, F.; CholewińSki, W.; Czepczynski, R.; Kubiak, A.; et al. (9 authors)


Rapid Detection of SARS-CoV-2 Antigens and Antibodies Using OFET Biosensors Based on a Soft and Stretchable Semiconducting Polymer

Ditte, K.; Nguyen Le, T. A.; Ditzer, O.; Isabel Sandoval Bojorquez, D.; Chae, S.; et al. (8 authors)


Molecular Response to Combined Molecular- and External Radiotherapy in Head and Neck Squamous Cell Carcinoma (HNSCC).

Rassamegevanon, T.; Feindt, L.; Koi, L.; Müller, J.; Freudenberg, R.; et al. (16 authors)


Rational Linker Design to Accelerate Excretion and Reduce Background Uptake of Peptidomimetic PSMA-Targeting Hybrid Molecules.

Eder, A.; Schäfer, M.; Schmidt, J.; Bauder-Wüst, U.; Roscher, M.; et al. (9 authors)


Leptin counteracts hypothermia in hypothyroidism through its pyrexic effects and by stabilizing serum thyroid hormone levels

Weiner, J.; Roth, L.; Kranz, M.; Brust, P.; Boelen, A.; et al. (13 authors)


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