Imaging and Radiooncology
Health > Cancer Research - All Topics
In Germany, 500,000 people are diagnosed with cancer every year. New, faster, and primarily more gentle diagnostic and therapeutic procedures can help to fight the disease and to save lifes.
Cancer research at the HZDR addresses the following topics: The scientists conduct research, for example, on new radiopharmaceuticals for the diagnosis of cancer and for the characterization of cancer tissue and, as a further development, also investigate substances for the cancer therapy of tomorrow. Our research has already resulted in the development of new substances. Two radiopharmaceuticals are officially approved and registered pursuant to the pharmaceutical law. These substances, which are produced at the HZDR and subsequently distributed on the market, are needed for the detection of tumors and metastases with a PET camera (PET = Positron Emission Tomography). That is also possible in Dresden – patients can be examined utilizing a full-body scan PET/MRI system which is the first of its kind to have been approved for patients in Germany. HZDR scientists are further developing and improving these innovative imaging procedures which are used in oncology.
They are also investigating particle acceleration with the help of innovative laser technologies. The objective: Making proton-therapy centers smaller while, at the same time, lowering the costs through more powerful lasers and with pulsed magnetic fields. Researchers are also aiming on monitoring irradiation of patients with proton beams in real time.
The HZDR is part of the Competence Network for Radiation Research (KVSF, promoted by the BMBF). This alliance promotes the sustainability of competences in the field of radiation research, in particular, by fostering young scientists.
Important partners are the TU Dresden (Dresden University of Technology) and the University Hospital Carl Gustav Carus Dresden. We jointly operate the OncoRay Center. More information on collaborations with Dresden and Heidelberg partners
Objectives
- Development and application of new technologies for the diagnosis and therapy of cancer
- Establishment of laser-accelerated ions in radiation oncology
- Monitoring and controlling tumor radiation in real time
- Continued development of individualized and tolerable therapy forms
Press Releases
- Kopf-Hals-Tumoren: Zeit für neue Einblicke in die individualisierte Krebstherapie
- Neubau bietet Wissenschaftlern und Ärzten optimale Infrastruktur für innovative Krebsforschung
- Bestrahlungserfolg bei Hirntumoren lässt sich mit kombinierter PET/MRT vorhersagen
- Forscher packen Alpha-Strahler in Käfig
- Stealth-cap technology for light-emitting nanoparticles
- High-contrast imaging for cancer therapy with protons
- New approach for range prediction improves accuracy of proton therapy
- Die Teilchenjägerin
- Der Spurenleger zum Tumor
- Directing nanoparticles straight to tumors
- Innovative ways to battle Parkinson’s disease
- Synthesis against the clock
- Vielversprechende Laborforschung
- Mit dem Lego-Prinzip gegen das Virus: HZDR-Wissenschaftler*innen erhalten millionenschwere Förderung für Corona-Forschung
- Staatsminister Christian Piwarz besuchte das HZDR
- NCT/UCC Dresden: Neubau für innovative Krebsforschung eröffnet
- Strahlender Helfer: HZDR und ROTOP stellen Radionuklid für Medikament zur Parkinson-Diagnostik her
- An important step towards live imaging in proton therapy
- HZDR und Monash University bauen gemeinsames Labor auf
- Strahlender Sieger dank strahlender Idee
- HZDR-Institut für Radiopharmazeutische Krebsforschung erhält Fördermittel für neues Forschungsgerät
- Glocker-Medaille für Dresdner Medizinphysiker
- Zelluläre Immuntherapien – Präzisionsmedizin gegen Krebs
- ProtOnART – a new consortium for proton online adaptive radiation therapy
- Radioactive Substances Fight Cancer in the Mini-lab
- Vision: Radiopharmaceutical Valley
- Mission to beat rare cancers: More targets on tumor cell surface for optimized radionuclide therapy
- Internationale Partnerschaft mit Monash University: Gemeinsames MHELTHERA-Labor gestartet
- Blockieren eines Eiweißmoleküls macht aggressive Hirntumoren sensibler für Strahlen- und Chemotherapie
- Smart Keys for cancer therapy: Research team develops new system for imaging and treating tumors
- A light in the dark: How the trajectory of protons is made visible
- Wegweisende CAR-T-Zelltherapie für Blutkrebs-Erkrankungen
- The world’s first Prototype for High-Contrast Live Imaging in Proton Therapy
- Neuer Ansatz bei schweren Verläufen von Prostatakrebs
- Krebs von innen bestrahlen: HZDR und DKFZ gründen Helmholtz-Verbund für Radiopharmazeutische Wissenschaften
- Radioaktivität rettet Leben
- HZDR trauert um Pius August Schubiger
- Innovative Immuntherapie gegen malignes Melanom: Neues Projekt soll mit KI-Hilfe die Hautkrebs-Behandlung verbessern
- Meilenstein für präklinische Bewertung neuer Radiopharmaka: HZDR erhält am Standort Leipzig hochauflösenden PET/MRT-Scanner
- Better understanding and treatment of brain tumors with the help of imaging: Andreas Maurer moves to the HZDR
- Multi-million funding for revolutionary radiation treatment for cancer: HZDR participates in research project UPLIFT
- Radiopharmazie: Strahlkraft made in Saxony
- New method for interactive 3D microscopy
Involved HZDR institutes
- Institute of Radiopharmaceutical Cancer Research
- Institute of Radiation Physics
- Institute of Radiooncology - OncoRay
- Dresden High Magnetic Field Laboratory
Collaborations
- OncoRay Center
- Nuclear Medicine Clinic at the University Hospital
- Deutsches Krebsforschungszentrum
- National Center for Tumor Diseases Dresden
Contacts
Publications
- Büttner, M.; Melton, P.; Fietkau, R. et al.
Successful implementation of online educational lectures of the German Society for Radiation Oncology (DEGRO)
Strahlentherapie und Onkologie 200(2024), 151-158 (10.1007/s00066-023-02162-x) - Linge, A.; Patil, S.; Grosser, M. et al.
The value of subcutaneous xenografts for individualised radiotherapy in HNSCC: Robust gene signature correlates with radiotherapy outcome in patients and xenografts
Radiotherapy and Oncology 191(2024), 110055 (10.1016/j.radonc.2023.110055) - Baumann, M.; Bacchus, C.; MC, A. et al.
Clinical research for global needs of radiation oncology
Radiotherapy and Oncology 190(2024), 110076 (10.1016/j.radonc.2023.110076) - Kirchner, J.; Plesca, I.; Rothe, R. et al.
Type I conventional dendritic cells and CD8(+) T cells predict favorable clinical outcome of head and neck squamous cell carcinoma patients
Frontiers in Immunology 15(2024), 1414298 (10.3389/fimmu.2024.1414298) - Baugh, J. N.; Veldhuijzen van Zanten, S.; Fiocco, M. et al.
Treatment-related survival patterns in diffuse intrinsic pontine glioma using a historical cohort: A report from the European Society for Pediatric Oncology DIPG/DMG Registry
Neuro-Oncology 6(2024), vdae155 (10.1093/noajnl/vdae155) - Knäusl, B.; Belotti, G.; Bertholet, J. et al.
A review of the clinical introduction of 4D particle therapy research concepts
Physics and Imaging in Radiation Oncology 29(2024), 100535 (10.1016/j.phro.2024.100535) - Mortensen, H. R.; Populaire, P.; Hoffmann, L. et al.
Proton versus photon therapy for esophageal cancer – A trimodality strategy
Radiotherapy and Oncology 190(2024), 109980 (10.1016/j.radonc.2023.109980) - Trnkova, P.; Dasu, A.; Placidi, L. et al.
Patterns of practice of image guided particle therapy for cranio-spinal irradiation: A site specific multi-institutional survey of European Particle Therapy Network
Physica Medica, European Journal of Medical Physics 123(2024), 103407 (10.1016/j.ejmp.2024.103407) - Philchenkov, A.; Dubrovska, A.
Cancer Stem Cells as a Therapeutic Target: Current Clinical Development and Future Prospective
Stem Cells 42(2024)3, 173-199 (10.1093/stmcls/sxad092) - Mehralivand, S.; Thomas, C.; Puhr, M. et al.
New advances of the androgen receptor in prostate cancer: report from the 1st International Androgen Receptor Symposium
Journal of Translational Medicine 22(2024), 71 (10.1186/s12967-024-04878-5) - Beier, A.-M. K.; Ebersbach, C.; Siciliano, T. et al.
Targeting the glutamine metabolism to suppress cell proliferation in mesenchymal docetaxel-resistant prostate cancer
Oncogene 43(2024), 2038 (10.1038/s41388-024-03059-4) - Subbarayan, K.; Al-Samadi, A.; Schäfer, H. et al.
Altered ACE2 and interferon landscape in the COVID-19 microenvironment correlate with the anti-PD-1 response in solid tumors
Cellular and Molecular Life Sciences 81(2024)473 (10.1007/s00018-024-05520-9) - Mehnert, E.; Möller, F.; Hofbauer, C. et al.
Palliative care of proximal femur metastatic disease and osteolytic lesions: results following surgical and radiation treatment
BMC Cancer 24(2024), 1431 (10.1186/s12885-024-13170-0) - Isaksson, L.; Mastroleo, F.; Vincini, M. et al.
The emerging role of Artificial Intelligence in proton therapy: a review
Critical Reviews in Oncology / Hematology 204(2024), 104485 (10.1016/j.critrevonc.2024.104485) - de Mendoza, A. M.; Michlikova, S.; Castro, P. S. et al.
Generalized, sublethal damage-based mathematical approach for improved modeling of clonogenic survival curve flattening upon hyperthermia, radiotherapy, and beyond
Physics in Medicine and Biology 70(2025), 025022 (10.1088/1361-6560/ada680) - Burger, E.-M.; Hauser, S.; Donat, C. et al.
Investigation of a GPC-3-addressing peptide as potential radioligand for PET imaging of HCC
Nuklearmedizin 63(2024)2, 154 (10.1055/s-0044-1782473) - Schädlich, J.; Ullrich, M.; Haase-Kohn, C. et al.
Radioiodinated closo-dicarbadodecaborane(12)-based cyclooxygenase-2/5-lipoxygenase inhibitors
EJNMMI Radiopharmacy and Chemistry 9(2024)Suppl 1, OP14 (10.1186/S41181-024-00294-8) - Trommer, J.; Kučka, J.; Vercellino, S. et al.
Radiolabeling of M13 bacteriophages for in vivo imaging
EJNMMI Radiopharmacy and Chemistry 9(2024), 65 (10.1186/s41181-024-00294-8) - Batool, A.; Duffin, R. N.; Burke, K. et al.
Bismuth Oxide Nanorings: A Potential Material for Hyperthermia-Based Tumor Therapy
ACS Applied Nano Materials 8(2025)1, 622-630 (10.1021/acsanm.4c05976) - Jarutyte, L.; Petr, J.; Turner, N. et al.
Advantages and challenges of using arterial spin labelling MRI to monitor cerebral blood flow in multi-centre clinical trials of neurodegenerative disease: Experience from the RADAR study
Cerebral Circulation, Cognition and Behavior 8(2025), 100376 (10.1016/j.cccb.2024.100376) - Eitler, J.; Rackwitz, W.; Wotschel, N. et al.
CAR-mediated targeting of NK cells overcomes tumor immune escape caused by ICAM-1 downregulation
Journal for ImmunoTherapy of Cancer 12(2024), e008155 (10.1136/jitc-2023-008155) - Ahmed, M.; Beyreuther, E.; Gantz, S. et al.
Design and dosimetric characterization of a transportable proton minibeam collimation system
Frontiers in Oncology 14(2024), 1473625 (10.3389/fonc.2024.1473625) - Urbanovský, P.; David, T.; Hlinová, V. et al.
Cross-bridged cyclam derivatives with bis(phosphinate) and phosphinate-phosphonate pendant arms (cb-BPC) as chelators for copper radioisotopes
Organic & Biomolecular Chemistry (2025) (10.1039/D4OB01473A) - Selg, C.; Gordić, V.; Krajnović, T. et al.
Re-design and evaluation of diclofenac-based carborane-substituted prodrugs and their anti-cancer potential
Scientific Reports 14(2024), 30488 (10.1038/s41598-024-81414-x) - Markl, A. M.; Nieder, D.; Sandoval Bojorquez, D. I. et al.
Heterogeneity of tumor biophysical properties and their potential role as prognostic markers.
Cancer Heterogeneity and Plasticity 1(2024)2, 0011 (10.47248/chp2401020011) - Tinganelli, W.; Puspitasari-Kokko, A.; Sokol, O. et al.
FLASH Bragg-peak irradiation with a therapeutic carbon ion beam: first in vivo results
International Journal of Radiation Oncology Biology Physics (2025) (10.1016/j.ijrobp.2024.11.089) - Naseer, S.; Abelleira-Hervas, L.; Savani, D. et al.
Traumatic Brain Injury Leads to Alterations in Contusional Cortical miRNAs Involved in Dementia
Biomolecules 12(2022)10, 1457 (10.3390/biom12101457) - May, H. G.; Tsikonofilos, K.; Donat, C. et al.
EEG hyperexcitability and hyperconnectivity linked to GABAergic inhibitory interneuron loss following traumatic brain injury
Brain Communications 6(2024)6, fcae385 (10.1093/braincomms/fcae385) - Clegg, J.; Curvello, R.; Gabrielyan, A. et al.
Tailoring metabolic activity assays for tumour-engineered 3D models
Biomaterials Advances 167(2025), 214116 (10.1016/j.bioadv.2024.214116) - Liolios, C.; Bouziotis, D.; Sihver, W. et al.
Synthesis and Preclinical Evaluation of a Bispecific PSMA-617/RM2 Heterodimer Targeting Prostate Cancer
ACS Medicinal Chemistry Letters 15(2024)11, 1970-1978 (10.1021/acsmedchemlett.4c00324) - Leikina, E.; Whitlock, J. M.; Melikov, K. et al.
Formation of multinucleated osteoclasts depends on an oxidized species of cell surface-associated La protein
eLife 13(2024)RP98665 (10.7554/eLife.98665) - Novy, Z.; Hajduova, K.; Petrik, M. et al.
Preclinical assessment of enhanced blood retention and tumor uptake PSMA-targeting 225Ac-labeled radioconjugates
EJNMMI Radiopharmacy and Chemistry 9(2024), OP30 (10.1186/s41181-024-00294-8) - Blei, M. K.; Drobot, B.; Stadlbauer, S. et al.
Synthesis, stability determination and radiolabeling of new diazabenzene-based azamacrocycles with barium-131, actinium-225, lanthanum-133, and lead-212
EJNMMI Radiopharmacy and Chemistry 9(2024), OP15 (10.1186/s41181-024-00294-8) - Palkowitsch, M.; Kaufmann, L.-M.; Hennings, F. et al.
Variable-RBE-induced NTCP predictions for various side-effects following proton therapy for brain tumors – Identification of high-risk patients and risk mitigation
Radiotherapy and Oncology 202(2025), 110590 (10.1016/j.radonc.2024.110590) - Vaxevanis, C.; Bachmann, M.; Seliger, B.
Immune modulatory microRNAs in tumors, their clinical relevance in diagnosis and therapy
Journal for ImmunoTherapy of Cancer 12(2024), e009774 (10.1136/jitc-2024-009774) - Vehlow, A.; Lange, I.; Lagies, S. et al.
Cytotoxic and Radiosensitizing Effects of European and African Propolis in 3D Lung Carcinoma Cell Cultures
Anticancer Research 44(2024)11, 4801-4811 (10.21873/anticanres.17306) - Besso, M. J.; Bitto, V.; Koi, L. et al.
Transcriptomic and epigenetic landscape of nimorazole-enhanced radiochemotherapy in head and neck cancer
Radiotherapy and Oncology 199(2024), 110348 (10.1016/j.radonc.2024.110348) - Gündel, D.; Teodoro, R.; Ludwig, F.-A. et al.
Development and Evaluation of Deuterated [18F]JHU94620 Isotopologues for the Non-invasive Assessment of the Cannabinoid type 2 Receptor in Brain
EJNMMI Radiopharmacy and Chemistry 9(2024), 91 (10.1186/s41181-024-00319-2) - Peters, N.; Taasti, V. T.; Ackermann, B. et al.
Response to “Letter regarding Consensus guide on CT-based prediction of stopping-power ratio using a Hounsfield look-up table for proton therapy”
Radiotherapy and Oncology 190(2024), 109961 (10.1016/j.radonc.2023.109961) - Brunner, J.; Langgartner, L.; Danhel, H. et al.
Dosimetric characteristics of 3D-printed and epoxy-based materials for particle therapy phantoms
Frontiers in Physics 12(2024), 1323788 (10.3389/fphy.2024.1323788) - Nazary, H.; Metternich, M.; Schumacher, D. et al.
Towards ion stopping power experiments with the laser-driven LIGHT beamline
Journal of Plasma Physics 90(2024)3, 905900302 (10.1017/S0022377824000576) - Scott, P.; Penuelas, I.; Rey, A. et al.
Highlight selection of radiochemistry and radiopharmacy developments by editorial board
EJNMMI Radiopharmacy and Chemistry 9(2024), 67 (10.1186/s41181-024-00296-6) - Metzger, G.; Bayerl, C.; Rogasch, J. et al.
68Ga-labeled fibroblast activation protein inhibitor (FAPI) PET/CT for locally advanced or recurrent pancreatic cancer staging and restaging after chemoradiotherapy
Theranostics 14(2024)11, 4184-4197 (10.7150/thno.95329) - Bela Andela, S.; Amthauer, H.; Furth, C. et al.
Quantitative PSMA-PET parameters in localized prostate cancer: prognostic and potential predictive value
Radiation Oncology 19(2024), 97 (10.1186/s13014-024-02483-w) - Oborn, B. M.; Semioshkina, E.; van der Kraaij, E. et al.
Simulation and experimental benchmarking of a proton pencil beam scanning nozzle for development of MRI-guided proton therapy
Medical Physics 51(2024)9, 6196-6205 (10.1002/mp.17279) - Padrela, B. E.; Slivka, M.; Sneve, M. H. et al.
Blood-brain barrier water permeability across the adult lifespan: A multi-echo ASL study
Neurobiology of Aging 147(2025), 176-186 (10.1016/j.neurobiolaging.2024.12.012) - Schott, M.; Vehlow, A.; Benka, M. et al.
Aqueous extracts from Dioscorea sansibarensis Pax show cytotoxic and radiosensitizing potential in 3D growing HPV-negative and HPV-positive human head and neck squamous cell carcinoma models
Biomedicine and Pharmacotherapy 179(2024), 117305 (10.1016/j.biopha.2024.117305) - Doctor, A.; Laube, M.; Meister, S. et al.
Combined PET radiotracer approach reveals insights into stro-mal cell-induced metabolic changes in pancreatic cancer in vitro and in vivo
Cancers 16(2024), 3393 (10.3390/cancers16193393) - Azizova, A.; Wamelink, I. J. H. G.; Prysiazhniuk, Y. et al.
Human Performance in Predicting Enhancement Quality of Gliomas Using Gadolinium-Free MRI Sequences
Journal of Neuroimaging 34(2024)6, 673-693 (10.1111/jon.13233) - Zegers, C.; Swinnen, A.; Roumen, C. et al.
High precision stereotactic irradiation for focal drug-resistant epilepsy versus standard treatment: a randomized waitlist-controlled trial (the PRECISION-trial)
Trials 25(2024), 334 (10.1186/s13063-024-08168-9) - Witzmann, K.; Raschke, F.; Wesemann, T. et al.
Diffusion decrease in normal-appearing white matter structures following photon or proton irradiation indicates differences in regional radiosensitivity
Radiotherapy and Oncology 199(2024), 110459 (10.1016/j.radonc.2024.110459) - Shahzadi, I.; Seidlitz, A.; Beuthien-Baumann, B. et al.
Radiomics for the detection of residual tumour status after surgery and patient outcome prediction after chemoradiotherapy in newly diagnosed glioblastoma based on [11C] methionine PET and T1c-w MRI
Scientific Reports 14(2024), 4576 (10.1038/s41598-024-55092-8) - Igbo, B. T.; Jentsch, C.; Linge, A. et al.
Correlation of microscopic tumor extension with tumor microenvironment in esophageal cancer patients
Strahlentherapie und Onkologie 200(2024), 595-604 (10.1007/s00066-024-02234-6) - Grau, C.; Dasu, A.; Troost, E. G. C. et al.
Towards a European prospective data registry for particle therapy
Radiotherapy and Oncology 196(2024), 110293 (10.1016/j.radonc.2024.110293) - Erb, H.; Polishchuk, N.; Stasyk, O. et al.
Glutamine metabolism and prostate cancer
Cancers 16(2024)16, 2871 (10.3390/cancers16162871) - Sihver, W.; Walther, M.; Ullrich, M. et al.
Cyclohexanediamine triazole (CHDT)-functionalization enables labeling of target molecules with Al18F / 68Ga / 111In
Bioconjugate Chemistry 35(2024)9, 1402-1416 (10.1021/acs.bioconjchem.4c00313) - Krönke, T.; Kopka, K.; Mamat, C.
Enhancing the radionuclide theranostic concept through the radiohybrid approach
RSC Medicinal Chemistry (2025) (10.1039/d4md00591k) - Rothe, R.; Xu, Y.; Wodtke, J. et al.
Programmable Release of Chemotherapeutics from Ferrocene-based Injectable Hydrogels Slows Melanoma Growth
Advanced Healthcare Materials 13(2024)27, 2400265 (10.1002/adhm.202400265) - Ullrich, M.; Wodtke, R.; Brandt, F. et al.
The heterobivalent (SSTR2/albumin) radioligand [67Cu]cCu-NODAGA-cLAB4-TATE enables efficient somatostatin receptor radionuclide theranostics
Theranostics 14(2024)14, 5371-5387 (10.7150/thno.100091) - Samarzija, I.; Lukiyanchuk, V.; Lončarić, M. et al.
The extracellular matrix component Perlecan/HSPG2 regulates radioresistance in prostate cancer cells
Frontiers in Cell and Developmental Biology 12(2024), 1452463 (10.3389/fcell.2024.1452463) - Maus, J.; Nikulin, P.; Hofheinz, F. et al.
Deep learning based bilateral filtering for edge-preserving denoising of respiratory-gated PET
EJNMMI Physics 11(2024), 58 (10.1186/s40658-024-00661-z) - Azizova, A.; Prysiazhniuk, Y.; Wamelink, I. J. H. G. et al.
Preoperative Prediction of Diffuse Glioma Type and Grade in Adults: a Gadolinium-Free MRI-Based Decision Tree
European Radiology (2025) (10.1007/s00330-024-11140-5) - Marie Benko, L.; Misko, V. R.; Baraban, L. et al.
Janus Particles in Acoustofluidic Setup: The Interplay between Self-Propulsion and Acoustic Trapping
Micro 4(2024)1, 185-195 (10.3390/micro4010013) - Sonam, S.; Jelača, S.; Laube, M. et al.
Carborane Conjugates with Ibuprofen, Fenoprofen and Flurbiprofen: Synthesis, Characterization, COX Inhibition Potential and In Vitro Activity
ChemMedChem 20(2025), e202400018 (10.1002/cmdc.202400018) - Ratliff, H. N.; Kögler, T.; Pausch, G. et al.
The Backscatter Gating method for time, energy, and position resolution characterization of long form factor organic scintillators
Journal of Instrumentation 19(2024)07, P07002 (10.1088/1748-0221/19/07/P07002) - Wang, J.; Wang, T.; Mou, T. et al.
Novel 18F-labeled benzimidazolone-based radioligands as highly selective sigma-2 receptor probes for tumor imaging
Journal of Medicinal Chemistry 67(2024)19, 17392-17406 (10.1021/acs.jmedchem.4c01315) - Schneider, M.; Schilz, J.; Schürer, M. et al.
SAPPHIRE - Establishment of Small Animal Proton and PHoton Image-guided Radiation Experiments
Physics in Medicine and Biology 69(2024)97, 095020 (10.1088/1361-6560/ad3887) - Kaushik, S.; Stützer, K.; Ödén, J. et al.
Adaptive intensity modulated proton therapy using 4D robust planning: a proof-of-concept for the application of dose mimicking approach
Physics in Medicine and Biology 69(2024)18, 185010 (10.1088/1361-6560/ad75e0) - Dijsselhof, M. B. J.; Holtrop, J.; James, S.-N. et al.
Associations of life-course cardiovascular risk factors with late-life cerebral haemodynamics
Journal of Cerebral Blood Flow and Metabolism (2025) (10.1177/0271678X241301261) - Samimi, R.; Kamali-Asl, A.; Ahmadyar, Y. et al.
Dual time-point [18F]FDG PET imaging for quantification of metabolic uptake rate: Evaluation of a simple, clinically feasible method
Physica Medica, European Journal of Medical Physics 121(2024), 103336 (10.1016/j.ejmp.2024.103336) - Brühlmann, S. A.; Walther, M.; Blei, M. K. et al.
Scalability Study on [133La]LaCl3 Production with a Focus on Potential Clinical Applications
EJNMMI Radiopharmacy and Chemistry 9(2024)1, 60 (10.1186/s41181-024-00292-w) - Makarevich, K.; Schellhammer, S.; Pausch, G. et al.
Proton bunch monitors for the clinical translation of prompt gamma-ray timing
Physics in Medicine and Biology 69(2024), 225013 (10.1088/1361-6560/ad8c96) - Hueso-González, F.; Berthold, J.; Wohlfahrt, P. et al.
Inter-center comparison of proton range verification prototypes with an anthropomorphic head phantom
Physics in Medicine and Biology 69(2024)22, 225010 (10.1088/1361-6560/ad8856) - Schniewind, I.; José Besso, M.; Klicker, S. et al.
Epigenetic Targeting to Overcome Radioresistance in Head and Neck Cancer
Cancers 16(2024), 730 (10.3390/cancers16040730) - Boutier, H.; Rodrigues Loureiro, L. R.; Hoffmann, L. et al.
UniCAR T-cell potency – A matter of affinity between Adaptor Molecules and Adaptor CAR T-cells?
International Journal of Molecular Sciences 25(2024)13, 7242 (10.3390/ijms25137242) - Blei, M. K.; Drobot, B.; Stadlbauer, S. et al.
Synthese, Stabilitätsbestimmung und Radiomarkierung neuer Pym-Azamakrozyklen mit Barium-131, Actinium-225, Lanthan-133, und Blei-212
Nuklearmedizin 63(2024), 91 (10.1055/s-0044-1782286) - Krönke, T.; Zarschler, K.; Reissig, F. et al.
Iod-123-basierte Radiohybridkonjugate als diagnostisches Match zur zielgerichteten Alphatherapie mit Actinium-225
Nuklearmedizin 63(2024), 111 (10.1055/s-0044-1782344) - Tee, M.; Padrela, B.; Dupeyron, M. et al.
Associations between Potential Risk Factors and Blood-brain Barrier Water Permeability in Middle-aged and Older Adults
Journal of Alzheimer's Disease (2025) (10.1177/13872877251314138) - Wamelink, I.; Azizova, A.; Booth, T. et al.
Rebuttal to the LET to be paired with RAD-24-0653, entitled Gadolinium Reduction in Brain Tumor Imaging: A Paradigm Shift in Diagnostic Strategies
Radiology (2024) (10.1148/radiol.240653) - Starke, S.; Kieslich, A. M.; Palkowitsch, M. et al.
A deep-learning-based surrogate model for Monte-Carlo simulations of the linear energy transfer in primary brain tumor patients treated with proton-beam radiotherapy
Physics in Medicine and Biology 69(2024), 165034 (10.1088/1361-6560/ad64b7) - Prysiazhniuk, Y.; Server, A.; Leske, H. et al.
Diffuse glioma molecular profiling with Arterial Spin Labeling and Dynamic Susceptibility Contrast perfusion MRI: a comparative study
Neuro-Oncology Advances 6(2024)1, vdae113 (10.1093/noajnl/vdae113) - Padrela, B.; Mahroo, A.; Tee, M. et al.
Developing blood-brain barrier arterial spin labelling as a non-invasive early biomarker of Alzheimer’s disease (DEBBIE-AD): a prospective observational multicohort study protocol
BMJ Open 14(2024)3, e081635 (10.1136/bmjopen-2023-081635) - Kubeil, M.; Neuber, C.; Starke, M. et al.
64Cu tumor labeling with hexadentate picolinic acid-based bispidine immunoconjugates
Chemistry - A European Journal 30(2024), e202400366 (10.1002/chem.202400366) - Weber, T.; Krönke, T.; Köckerling, M. et al.
Towards the Stable Binding of Mercury: Synthesis and Functionalization of Dibenzyldiazabicyclononane Scaffolds
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The Chemotype of Chromanones as a Privileged Scaffold for Multineurotarget Anti-Alzheimer Agents
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Combined Systemic Drug Treatment with Proton Therapy: Investigations on Patient-Derived Organoids
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Integration of p16/HPV DNA Status with a 24-miRNA-Defined Molecular Phenotype Improves Clinically Relevant Stratification of Head and Neck Cancer Patients
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Targeting of p21-Activated Kinase 4 Radiosensitizes Glioblastoma Cells via Impaired DNA Repair
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Efficient Production of the PET radionuclide 133La for Theranostic Purposes in Targeted Alpha Therapy using the 134Ba(p,2n)133La Reaction
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Exploring nitric oxide (NO)- releasing celecoxib derivatives as modulators of radioresponse in pheochromocytoma cells
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Changes in Radical Levels as a Cause for the FLASH effect: Impact of beam structure parameters at ultra-high dose rates on oxygen depletion in water
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Development of Radiotracers for Imaging of the PD-1/PD-L1 Axis
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