Publications of Institute of Radiopharmaceutical Cancer Research

903 Publications

2019

Carboranyl Analogues of Celecoxib with Potent Cytostatic Activity against Human Melanoma and Colon Cancer Cell Lines
Buzharevski, A.; Paskas, S.; Sárosi, M. B.; Laube, M.; Lönnecke, P.; Neumann, W.; Mijatovic, S.; Maksimovic-Ivanic, D.; Pietzsch, J.ORC; Hey-Hawkins, E.

Fluorine-18 labeling of S100 proteins for small animal positron emission tomography
Laube, M.; Kniess, T.; Neuber, C.; Haase-Kohn, C.; Pietzsch, J.ORC
  • Book chapter
    Claus W. Heizmann: Calcium-Binding Proteins of the EF-Hand Superfamily: From Basics to Medical Applications, New York, NY: Humana Press, 2019, 978-1-4939-9029-0, 461-485
    DOI: 10.1007/978-1-4939-9030-6_29
  • Methods in Molecular Biology 1929(2019), 461-485
    DOI: 10.1007/978-1-4939-9030-6_29

FDG-PET/MRI in patients with pelvic recurrence of rectal cancer: first clinical experiences
Plodeck, V.; Rahbari, N.; Weitz, J.; Radosa, C.; Laniado, M.; Hoffmann, R.; Zoephel, K.; Beuthien-Baumann, B.; Kotzerke, J.; Hoff, J. van den; Platzek, I.;

Targeting cyclic nucleotide phosphodiesterase 5 (PDE5) in brain: Toward the development of a PET radioligand labeled with fluorine-18
Wenzel, B.; Liu, J.; Dukic-Stefanovic, S.; Deuther-Conrad, W.; Teodoro, R.; Ludwig, F.-A.; Chezal, J.-M.; Moreau, E.; Brust, P.; Maisonial-Besset, A.;

Synthesis, 18F-labelling and radiopharmacological characterisation of the C-terminal 30mer of Clostridium perfringens enterotoxin as a potential claudin-targeting peptide
Löser, R.; Bader, M.; Kuchar, M.; Wodtke, R.; Lenk, J.; Wodtke, J.; Kuhne, K.; Bergmann, R.; Haase-Kohn, C.; Urbanová, M.; Steinbach, J.; Pietzsch, J.;

Cathepsin B: Active Site Mapping with Peptidic Substrates and Inhibitors
Schmitz, J.; Gilberg, E.; Löser, R.; Bajorath, J.; Bartz, U.; Gütschow, M.;

Access to 18F-labelled isoxazoles by Ruthenium-promoted 1,3-dipolar cycloaddition of 4-[18F]fluoro-N-hydroxybenzimidoyl chloride with alkynes.
Roscales, S.ORC; Kniess, T.ORC
  • Journal of Labelled Compounds and Radiopharmaceuticals (2019)
    Online First (2019) DOI: 10.1002/jlcr.3708

Prognostic value of SUR in patients with trimodality treatment of locally advanced esophageal carcinoma
Bütof, R.; Hofheinz, F.; Zöphel, K.; Schmollack, J.; Jentsch, C.; Zschaeck, S.; Kotzerke, J.; van den Hoff, J.; Michael Baumann, M.;

Studies towards the development of a PET radiotracer for imaging of the P2Y1 receptors in the brain: synthesis, 18F-labeling and preliminary biological evaluation
Moldovan, R.-P.; Wenzel, B.; Teodoro, R.; Neumann, W.; Dukic-Stefanovic, S.; Deuther-Conrad, W.; Hey-Hawkins, E.; Krügel, U.; Brust, P.;

2018

Pretherapeutic FDG–PET total metabolic tumor volume predicts response to induction therapy in pediatric Hodgkin’s lymphoma
Rogasch, J.; Hundsdoerfer, P.; Hofheinz, F.; Wedel, F.; Schatka, I.; Amthauer, H.; Furth, C.;

Evaluation of Brain Nuclear Medicine Imaging Tracers in a Murine Model of Sepsis-Associated Encephalopathy
Szöllősi, D.; Hegedűs, N.; Veres, D. S.; Futó, I.; Horváth, I.; Kovács, N.; Martinecz, B.; Dénes, Á.; Seifert, D.; Bergmann, R.; Lebeda, O.; Varga, Z.; Kaleta, Z.; Szigeti, K.; Máthé, D.;

Immune Monitoring of Cancer Patients Prior to and During CTLA-4 or PD-1/PD-L1 Inhibitor Treatment
Tunger, A.; Kießler, M.; Wehner, R.; Temme, A.; Meier, F.; Bachmann, M.; Schmitz, M.;

Multimodal PET/MRI Imaging Results Enable Monitoring the Side Effects of Radiation Therapy.
Kovács, N.; Szigeti, K.; Hegedűs, N.; Horváth, I.; Veres, D. S.; Bachmann, M.; Bergmann, R.; Máthé, D.;

In vivo confirmation of altered hepatic glucose metabolism in patients with liver fibrosis/cirrhosis by 18F-FDG PET/CT
Verloh, N.; Einspieler, I.; Utpatel, K.; Menhart, K.; Brunner, S.; Hofheinz, F.; van den Hoff, J.; Wiggermann, P.; Evert, M.; Stroszczynski, C.; Hellwig, D.; Grosse, J.;

Synthesis, Receptor Affinity, and Antiallodynic Activity of Spirocyclic σ Receptor Ligands with Exocyclic Amino Moiety
Bergkemper, M.; Kronenberg, E.; Thum, S.; Börgel, F.; Daniliuc, C.; Schepmann, D.; Nieto, F. R.; Brust, P.; Reinoso, R. F.; Alvarez, I.; Wünsch, B.;

Diverse Effects of Phospholipase A2 Receptor Expression on LNCaP and PC-3 Prostate Cancer Cell Growth in vitro and in vivo
Friedemann, M.; Nacke, B.; Hagelgans, A.; Jandeck, C.; Bechmann, N.; Ullrich, M.; Belter, B.; Neuber, C.; Sukocheva, O.; Pietzsch, J.ORC; Menschikowski, M.

Towards Utilising Photocrosslinking of Polydiacetylenes for the Preparation of “Stealth” Upconverting Nanoparticles
Nsubuga, A.; Zarschler, K.ORC; Sgarzi, M.ORC; Graham, B.; Stephan, H.ORC; Joshi, T.ORC

Improved Conjugation, 64-Cu Radiolabeling, in Vivo Stability, and Imaging Using Nonprotected Bifunctional Macrocyclic Ligands: Bis(Phosphinate) Cyclam (BPC) Chelators
David, T.; Hlinová, V.; Kubíček, V.; Bergmann, R.; Striese, F.; Berndt, N.; Szöllösi, D.; Hegedus, N.; Mathe, D.; Bachmann, M.; Pietzsch, H.-J.; Hermann, P.;

Cognitive correlates of a4b2 nicotinic acetylcholine receptors in mild Alzheimer’s dementia
Sabri, O.; Meyer, P. M.; Graef, S.; Hesse, S.; Wilke, S.; Becker, G.-A.; Rullmann, M.; Patt, M.; Luthardt, J.; Gudrun Wagenknecht, G.; Hoepping, A.; Smits, R.; Franke, A.; Sattler, B.; Tiepolt, S.; Fischer, S.; Deuther-Conrad, W.; Hegerl, U.; Barthel, H.; Schoenknecht, P.; Brust, P.;

Fourier Analysis of Cerebral Metabolism of Glucose: Gender Differences in Mechanisms of Color Processing in the Ventral and Dorsal Streams in Mice
Njemanze, P. C.; Kranz, M.; Brust, P.;

NMR-based investigations of acyl-functionalized piperazines concerning their conformational behavior in solution
Steinberg, J.; Köckerling, M.; Wodtke, R.; Löser, R.; Mamat, C.ORC

Synthesis, characterization and initial biological evaluation of [⁹⁹ᵐTc]Tc-tricarbonyl labeled DPA-α-MSH peptide derivatives for potential melanoma imaging
Gao, F.; Sihver, W.ORC; Bergmann, R.; Belter, B.; Bolzati, C.; Salvarese, N.; Steinbach, J.; Pietzsch, J.; Pietzsch, H.-J.

Exploring pitfalls of 64Cu‑labeled EGFR‑targeting peptide GE11 as a potential PET tracer
Striese, F.; Sihver, W.ORC; Gao, F.; Bergmann, R.; Walther, M.; Pietzsch, J.; Steinbach, J.; Pietzsch, H.-J.

Development of a novel target module redirecting UniCAR T cells to Sialyl Tn-expressing tumor cells
Loureiro, L.; Feldmann, A.; Bergmann, R.; Koristka, S.; Berndt, N.; Arndt, C.; Pietzsch, J.; Novo, C.; Videira, P.; Bachmann, M.;

Strain-specific metastatic phenotypes in pheochromocytoma allograft mice
Ullrich, M.; Liers, J.; Peitzsch, M.; Feldmann, A.; Bergmann, R.; Sommer, U.; Richter, S.; Bornstein, S. R.; Bachmann, M.; Eisenhofer, G.; Ziegler, C. G.; Pietzsch, J.ORC

Development of a selective and highly sensitive fluorescence assay for nucleoside triphosphate diphosphohydrolase1 (NTPDase1, CD39)
Lee, S.-Y.; Luo, X.; Namasivayam, V.; Geiss, J.; Mirza, S.; Pelletier, J.; Stephan, H.; Sevigny, J.; Müller, C. E.;

Cerebrovascular Reactivity during Prolonged Breath-Hold in Experienced Freedivers
Keil, V.; Eichhorn, L.; Mutsaerts, H.; Träber, F.; Block, W.; Mädler, B.; van de Ven, K.; Siero, J.; Macintosh, B.; Petr, J.; Fimmers, R.; Schild, H.; Hattingen, E.;

Contilisant, a Tetratarget Small Molecule for Alzheimer’s Disease Therapy Combining Cholinesterase, Monoamine Oxidase Inhibition and H3R Antagonism with Sigma 1R Agonism Profile
Bautista-Aguilera, O. M.; Budni, J.; Mina, F.; Medeiros, E. B.; Deuther-Conrad, W.; Entrena, J. M.; Moraleda, I.; Iriepa, I.; López-Muñoz, F.; Marco-Contelles, J.;

From mono- to bivalent: improving theranostic properties of target modules for redirection of UniCAR T cells against EGFR-expressing tumor cells in vitro and in vivo
Albert, S.; Arndt, C.; Koristka, S.; Berndt, N.; Bergmann, R.; Feldmann, A.; Schmitz, M.; Pietzsch, J.; Steinbach, J.; Bachmann, M.;

Cognitive correlates of α4β2 nicotinic acetylcholine receptors in mild Alzheimer's dementia
Sabri, O.; Meyer, P. M.; Gräf, S.; Hesse, S.; Wilke, S.; Becker, G.-A.; Rullmann, M.; Patt, M.; Luthardt, J.; Wagenknecht, G.; Hoepping, A.; Smits, R.; Franke, A.; Sattler, B.; Tiepolt, S.; Fischer, S.; Deuther-Conrad, W.; Hegerl, U.; Barthel, H.; Schönknecht, P.; Brust, P.;

Radiosynthesis and in vivo evaluation of a fluorine-18 labeled pyrazine based radioligand for PET imaging of the adenosine A2B receptor
Lindemann, M.; Hinz, S.; Deuther-Conrad, W.; Namasivayam, V.; Dukic-Stefanovic, S.; Teodoro, R.; Toussaint, M.; Kranz, M.; Juhl, C.; Steinbach, J.; Brust, P.; Müller, C. E.; Wenzel, B.;

Monitoring scanner calibration using the image derived arterial blood SUV in whole-body FDG-PET
Maus, J.ORC; Hofheinz, F.; Apostolova, I.; Kreissl, M. C.; Kotzerke, J.; van den Hoff, J.
Related publications
Assessment of in vivo PET quantification accuracy using… (Id 27391) is a supplement to this publication

Increased evidence for the prognostic value of late-treatment FDG-PET uptake in non-tumor affected oesophagus in irradiated patients with oesophageal carcinomas
Li, Y.; Hofheinz, F.; Furth, C.; Lili, C.; Hua, W.; Ghadjar, P.; Zschaeck, S.;

Effects of systematic partial volume errors on the computation of mean gray matter cerebral blood flow with Arterial Spin Labeling MRI
Petr, J.; Mutsaerts, H. J. M. M.; de Vita, E.; Steketee, R. M. E.; Smits, M.; Nederveen, A. J.; Hofheinz, F.; van den Hoff, J.; Asllani, I.;

Preyssler-Pope-Jeannin Polyanions [NaP5W30O110]14- and [AgP5W30O110]14-: Synthesis, Structural Characterization, Electrochemistry, Antiproliferative and Antibacterial Activity
Haider, A.; Zarschler, K.; Joshi, S. A.; Smith, R.; Lin, Z.; Mougharbel, A.; Herzog, U.; Müller, C. E.; Stephan, H.; Kortz, U.;

Synthesis and radiofluorination of novel fluoren-9-one based derivatives for the imaging of α7 nicotinic acetylcholine receptor with PET
Teodoro, R.; Scheunemann, M.; Wenzel, B.; Peters, D.; Deuther-Conrad, W.; Brust, P.;

Molekulare Bildgebung in der Onkologie mittels Positronen-Emissions-Tomographie
Derlin, T.; Grünwald, V.; Steinbach, J.; Wester, H.-J.; Ross, T. L.;

Harnessing the Coordination Chemistry of 1,4,7-Triazacyclononane for Biomimicry and Radiopharmaceutical Applications
Joshi, T.; Kubeil, M.ORC; Nsubuga, A.; Singh, G.ORC; Gasser, G.ORC; Stephan, H.ORC

Clinical translation and regulatory aspects of CAR/TCR-based adoptive cell therapies-the German Cancer Consortium approach.
Krackhardt, A. M.; Anliker, B.; Hildebrandt, M.; Bachmann, M.; Eichmüller, S. B.; Nettelbeck, D. M.; Renner, M.; Uharek, L.; Willimsky, G.; Schmitt, M.; Wels, W. S.; Schüssler-Lenz, M.;

Nε-Acryloyllysine piperazides as irreversible inhibitors of transglutaminase 2 – synthesis, structure-activity relationships and pharmacokinetic profiling
Wodtke, R.; Hauser, C.; Ruiz-Gómez, G.; Jäckel, E.; Bauer, D.; Lohse, M.; Wong, A.; Pufe, J.; Ludwig, F.-A.; Fischer, S.; Hauser, S.; Greif, D.; Pisabarro, M. T.; Pietzsch, J.; Pietsch, M.; Löser, R.;

Biodistribution studies of ultrasmall silicon nanoparticles and carbon dots in experimental rats and tumor mice
Licciardello, N.; Hunoldt, S.; Bergmann, R.; Singh, G.; Mamat, C.; Faramus, A.; Ddungu, J. L. Z.; Silvestrini, S.; Maggini, M.; de Cola, L.; Stephan, H.;

Overexpression of receptor tyrosine kinase EphB4 triggers tumor growth and hypoxia in A375 melanoma xenografts: insights from multitracer small animal imaging experiments
Neuber, C.; Belter, B.; Meister, S.; Hofheinz, F.; Bergmann, R.; Pietzsch, H.-J.; Pietzsch, J.ORC

Modified Calix[4]crowns as Molecular Receptors for Barium
Steinberg, J.; Bauer, D.; Reissig, F.; Köckerling, M.; Pietzsch, H.-J.; Mamat, C.ORC

Exploring the Metabolism of (+)-[18F]Flubatine in vitro and in vivo: LC-MS/MS aided Identification of Radiometabolites in a Clinical PET Study
Ludwig, F.-A.; Fischer, S.; Smits, R.; Deuther-Conrad, W.; Hoepping, A.; Tiepolt, S.; Patt, M.; Sabri, O.; Brust, P.;

Facile Preparation of Multifunctionalisable ‘Stealth’ Upconverting Nanoparticles for Biomedical Applications
Nsubuga, A.; Sgarzi, M.ORC; Zarschler, K.ORC; Kubeil, M.ORC; Hübner, R.; Steudtner, R.; Graham, B.; Joshi, T.; Stephan, H.ORC

Investigation of an 18F-labelled Imidazopyridotriazine for Molecular Imaging of Cyclic Nucleotide Phosphodiesterase 2A
Schröder, S.; Wenzel, B.; Deuther-Conrad, W.; Teodoro, R.; Kranz, M.; Scheunemann, M.; Egerland, U.; Höfgen, N.; Briel, D.; Steinbach, J.; Brust, P.;

Bridging from Brain to Tumor imaging: (S)- and (R)-[18F]Fluspidine for investigation of Sigma-1 Receptors in Tumor-bearing Mice
Kranz, M.; Bergmann, R.; Kniess, T.; Belter, B.; Neuber, C.; Cai, Z.; Deng, G.; Fischer, S.; Steinbach, J.; Zhou, J.; Huang, H.; Brust, P.; Deuther-Conrad, W.; Pietzsch, J.;

Spectroscopic Studies on Photoinduced Reactions of the Anticancer Prodrug, trans,trans,trans-[Pt(N3)2(OH)2(py)2]
Vernooij, R. R.; Joshi, T.; Horbury, M. D.; Graham, B.; Izgorodina, E. I.; Stavros, V. G.; Sadler, P. J.; Spiccia, L.; Wood, B. R.;

Causative treatment of acid aspiration induced acute lung injury – recent trends from animal experiments and critical perspective
Gramatté, J.; Pietzsch, J.ORC; Bergmann, R.; Richter, T.
  • Open Access LogoClinical Hemorheology and Microcirculation 69(2018), 187-195
    DOI: 10.3233/CH-189113

Engrafting human regulatory T cells with a flexible modular chimeric antigen receptor technology
Koristka, S.; Kegler, A.; Bergmann, R.; Arndt, C.; Feldmann, A.; Albert, S.; Cartellieri, M.; Ehninger, A.; Ehninger, G.; Middeke, J. M.; Bornhäuser, M.; Schmitz, M.; Pietzsch, J.; Akgün, K.; Ziemssen, T.; Steinbach, J.; Bachmann, M. P.;

Rapid synthesis of sub-10 nm hexagonal NaYF4-based upconverting nanoparticles using Therminol 66
Hesse, J.; Klier, D. T.; Sgarzi, M.; Nsubuga, A.; Bauer, C.; Grenzer, J.; Hübner, R.; Wislicenus, M.; Joshi, T.; Kumke, M. U.; Stephan, H.ORC

Photon vs. proton radiochemotherapy: effects on brain tissue volume and perfusion
Petr, J.; Platzek, I.; Hofheinz, F.; Mutsaerts, H.; Asllani, I.; van Osch, M.; Seidlitz, A.; Krukowski, P.; Gommlich, A.; Beuthien-Baumann, B.; Jentsch, C.; Maus, J.; Troost, E.; Baumann, M.; Krause, M.; van den Hoff, J.;

Chelation of heavy group 2 (radio)metals by p-tert-butylcalix[4]arene-1,3-crown-6 and logK determination via NMR
Bauer, D.; Gott, M.; Steinbach, J.; Mamat, C.ORC

Evaluation of fluorine-18-labelled alpha1(I)-N-telopeptide analogues as substrate-based radiotracers for PET imaging of melanoma-associated lysyl oxidase
Kuchar, M.; Neuber, C.; Belter, B.; Bergmann, R.; Lenk, J.; Wodtke, R.; Kniess, T.; Steinbach, J.; Pietzsch, J.; Löser, R.;

Facile Silylation of Cyclitols using Silyl-bis(triflates)
Topp, A.; Köckerling, M.ORC; Reinke, H.; Miethchen, R.; Mamat, C.ORC

Comparison of arterial spin labeling registration strategies in the multi-center GENetic frontotemporal dementia initiative (GENFI)
Mutsaerts, H. J. M. M.; Petr, J.; Thomas, D. L.; de Vita, E.; Cash, D. M.; van Osch, M. J. P.; Golay, X.; Groot, P. F. C.; Ourselin, S.; van Swieten, J.; Laforce, R.; Tagliavini, F.; Borroni, B.; Galimberti, D.; Rowe, J. B.; Graff, C.; D. Pizzini, F. B.; Finger, E.; Sorbi, S.; Castelo Branco, M.; Rohrer, J. D.; Masellis, M.; Macintosh, B. J.;

A Bayesian Approach for Measurements of Stray Neutrons at Proton Therapy Facilities: Quantifying Neutron Dose Uncertainty
Dommert, M.; Reginatto, M.; Zboril, M.; Fiedler, F.; Helmbrecht, S.; Enghardt, W.; Lutz, B.;

Recent Progress using the Staudinger Ligation for Radiolabeling Applications
Mamat, C.ORC; Gott, M.; Steinbach, J.ORC
  • Journal of Labelled Compounds and Radiopharmaceuticals 61(2018), 165-178
    DOI: 10.1002/jlcr.3562

Novel Valdecoxib Derivates by Ruthenium-catalyzed 1,3-Dipolar Cycloaddition of Nitrile Oxides with Alkynes - Synthesis and COX-2 Inhibition Affinity.
Roscales, S.; Bechmann, N.; Weiss, D. H.; Köckerling, M.; Pietzsch, J.; Kniess, T.;

Structural and kinetic considerations for the application of the traceless Staudinger ligation to future 18F radiolabeling using XRD and 19F-NMR
Köckerling, M.; Mamat, C.;

2017

Synthesis and Pharmacological Evaluation of Identified and Putative Metabolites of the A₁ Adenosine Receptor Antagonist 8-Cyclopentyl-3-(3-fluoropropyl)-1-propylxanthine (CPFPX)
Holschbach, M. H.; Bier, D.; Sihver, W.ORC; Schulze, A.; Neumaier, B.

Quantification: there is more to worry about than good scanner hardware and reliable calibration
Kotzerke, J.; van den Hoff, J.;

Maternal immune activation results in complex microglial transcriptome signature in the adult offspring that is reversed by minocycline treatment
Mattei, D.; Ivanov, A.; Ferrai, C.; Jordan, P.; Guneykaya, D.; Buonfiglioli, A.; Schaafsma, W.; Przanowski, P.; Deuther-Conrad, W.; Brust, P.; Hesse, S.; Patt, M.; Sabri, O.; Ross, T. L.; Eggen, B. J. L.; Bodecke, E. W. G. M.; Kaminska, B.; Beule, D.; Pombo, A.; Kettenmann, H.; Wolf, S. A.;

An orthotopic xenograft model for high-risk non-muscle invasive bladder cancer in mice: influence of mouse strain, tumor cell count, dwell time and bladder pretreatment
Huebner, D.; Rieger, C.; Bergmann, R.; Ullrich, M.; Meister, S.; Toma, M.; Wiedemuth, R.; Temme, A.; Novotny, V.; Wirth, M. P.; Bachmann, M.; Pietzsch, J.ORC; Fuessel, S.

Nitric oxide-releasing selective cyclooxygenase-2 inhibitors as promising radiosensitizers in melanoma cells in vitro
Bechmann, N.; Hauser, S.; Hofheinz, F.; Kniess, T.; Pietzsch, J.ORC
  • Open Access LogoAnnals of Radiation Therapy and Oncology 1(2017)2, 1010

Potential of asphericity as a novel diagnostic parameter in the evaluation of patients with Ga-68-PSMA-HBED-CC PET-positive prostate cancer lesions
Meissner, S.; Janssen, J.; Prasad, V.; Brenner, W.; Diederichs, G.; Hamm, B.; Hofheinz, F.; Makowski, M.;

Exploratory investigation of PSCA-protein expression in primary breast cancer patients reveals a link to HER2/neu overexpression.
Link, T.; Kuithan, F.; Ehninger, A.; Kuhlmann, J. D.; Kramer, M.; Werner, A.; Gatzweiler, A.; Richter, B.; Ehninger, G.; Baretton, G.; Bachmann, M.; Wimberger, P.; Friedrich, K.;

Mass spectrometry-based identification of a naturally presented receptor tyrosine kinase-like orphan receptor 1-derived epitope recognized by CD8+ cytotoxic T cells
Heidenreich, F.; Rücker-Braun, E.; Walz, J. S.; Eugster, A.; Kühn, D.; Dietz, S.; Nelde, A.; Tunger, A.; Wehner, R.; Link, C. S.; Middeke, J. M.; Stölzel, F.; Tonn, T.; Stevanovic, S.; Rammensee, H. G.; Bonifacio, E.; Bachmann, M.; Zeis, M.; Ehninger, G.; Bornhäuser, M.; Schetelig, J.; Schmitz, M.;

Novel Radiolabeled Bisphosphonates for PET Diagnosis and Endoradiotherapy of Bone Metastases
Pfannkuchen, N.; Meckel, M.; Bergmann, R.; Bachmann, M.; Bal, C.; Sathekge, M.; Mohnike, W.; Baum, R. P.; Rösch, F.;

Biological characterization of novel nitroimidazole-peptide conjugates in vitro and in vivo.
Bergmann, R.; Splith, K.; Pietzsch, J.; Bachmann, M.; Neundorf, I.;

Characterization of a switchable chimeric antigen receptor platform in a pre-clinical solid tumor model
Bejestani, E. P.; Cartellieri, M.; Bergmann, R.; Ehninger, A.; Loff, S.; Kramer, M.; Spehr, J.; Dietrich, A.; Feldmann, A.; Albert, S.; Wermke, M.; Baumann, M.; Krause, M.; Bornhäuser, M.; Ehninger, G.; Bachmann, M.; von Bonin, M.;

Retargeting of UniCAR T cells with an in vivo synthesized target module directed against CD19 positive tumor cells
Bachmann, D.; Aliperta, R.; Bergmann, R.; Feldmann, A.; Koristka, S.; Arndt, C.; Loff, S.; Welzel, P. B.; Albert, S.; Kegler, A.; Ehninger, A.; Cartellieri, M.; Ehninger, G.; Bornhäuser, M.; von Bonin, M.; Werner, C.; Pietzsch, J.; Steinbach, J.; Bachmann, M.;

Preparation of 18F-labeled building blocks for peptide conjugation using the "minimalist" approach
Omrane, M. A.; Zlatopolskiy, B. D.; Urusova, E.; Mamat, C.; Feni, L.; Neundorf, I.; Neumaier, B.;
  • Poster
    22nd International Symposium on Radiopharmaceutical Sciences (ISRS 2017), Dresden, 14.-19.05.2017, Dresden, Deutschland
  • Open Access LogoJournal of Labelled Compounds and Radiopharmaceuticals 60(2017)S1, S261
    DOI: 10.1002/jlcr.3508

Evaluation of Ba/Ra Polyoxopalladates for Radiopharmaceutical Applications
Gott, M.; Yang, P.; Kortz, U.; Pietzsch, H.-J.; Steinbach, J.; Mamat, C.;
  • Poster
    22nd International Symposium on Radiopharmaceutical Sciences (ISRS 2017), Dresden, 14.-19.05.2017, Dresden, Deutschland
  • Open Access LogoJournal of Labelled Compounds and Radiopharmaceuticals 60(2017)S1, S559
    DOI: 10.1002/jlcr.3508

Novel Functionalized Calixarenes as Host Molecules for Complexation with Alkaline Earth Metals
Steinberg, J.; Gott, M.; Pietzsch, H.-J.; Steinbach, J.; Mamat, C.;
  • Poster
    22nd International Symposium on Radiopharmaceutical Sciences (ISRS 2017), Dresden, 14.-19.05.2017, Dresden, Deutschland
  • Open Access LogoJournal of Labelled Compounds and Radiopharmaceuticals 60(2017)S1, S488
    DOI: 10.1002/jlcr.3508

Detection of Auger Electron Induced Strand Breaks on Plasmid DNA Caused by Technetium-99m Labeled Pyrene Derivatives
Wunderlich, G.; Reissig, F.; Mamat, C.; Pietzsch, H.-J.; Kotzerke, J.; Steinbach, J.;
  • Poster
    22nd International Symposium on Radiopharmaceutical Sciences (ISRS 2017), Dresden, 14.-19.05.2017, Dresden, Deutschland
  • Open Access LogoJournal of Labelled Compounds and Radiopharmaceuticals 60(2017)S1, S365
    DOI: 10.1002/jlcr.3508

Development of novel target modules for retargeting of UniCAR T cells to GD2 positive tumor cells
Mitwasi, N.; Feldmann, A.; Bergmann, R.; Berndt, N.; Arndt, C.; Koristka, S.; Kegler, A.; Jureczek, J.; Hoffmann, A.; Ehninger, A.; Cartellieri, M.; Albert, S.; Rössig, C.; Ehninger, G.; Pietzsch, J.; Steinbach, J.; Bachmann, M.;

Synthesis and X-ray Crystal Structure of N’-Cyano-N,N’-dimethyl-4-nitrobenzohydrazide
Löser, R.ORC; Pitzschler, R.; Köckerling, M.

Individualized risk assessment in neuroblastoma: does the tumoral metabolic activity on 123I-MIBG SPECT predict the outcome?
Rogasch, J.; Hundsdoerfer, P.; Furth, C.; Wedel, F.; Hofheinz, F.; Krüger, P.; Lode, H.; Brenner, W.; Eggert, A.; Amthauer, H.; Schatka, I.;

Increased FDG uptake on late-treatment PET in non-tumour-affected oesophagus is prognostic for pathological complete response and disease recurrence in patients undergoing neoadjuvant radiochemotherapy
Zschaeck, S.; Hofheinz, F.; Zöphel, K.; Bütof, R.; Jentsch, C.; Schmollack, J.; Löck, S.; Kotzerke, J.; Baretton, G.; Weitz, J.; Baumann, M.; Krause, M.;

PET Imaging Evaluation of Four sigma1 Radiotracers in Nonhuman Primates
Baum, E.; Cai, Z.; Bois, F.; Holden, D.; Lin, S.-F.; Lara-Jaime, T.; Kapinos, M.; Chen, Y.; Deuther-Conrad, W.; Fischer, S.; Dukic-Stefanovic, S.; Bunse, P.; Wünsch, B.; Brust, P.; Jia, H.; Huang, Y.;
  • Open Access LogoJournal of Nuclear Medicine 58(2017)6, 982

1‑(4‑[18F]Fluorobenzyl)-4-[(tetrahydrofuran-2-yl)methyl]piperazine: A Novel Suitable Radioligand with Low Lipophilicity for Imaging σ1 Receptors in the Brain
He, Y.; Xie, F.; Ye, J.; Deuther-Conrad, W.; Cui, B.; Wang, L.; Lu, J.; Steinbach, J.; Brust, P.; Huang, Y.; Lu, J.; Jia, H.;

18F-Labeled indole-based analogs as highly selective radioligands for imaging sigma-2 receptors in the brain
Wang, L.; Ye, J.; He, Y.; Deuther-Conrad, W.; Zhang, J.; Zhang, X.; Cui, M.; Steinbach, J.; Huang, Y.; Brust, P.; Jia, H.;

99mTechnetium-based Small Molecule Radiopharmaceuticals and Radiotracers Targeting Inflammation and Infection
Kniess, T.ORC; Laube, M.; Wüst, F.; Pietzsch, J.

Test-retest variability of lesion SUV and lesion SUR in 18F-FDG PET: an analysis of data from two prospective multicenter trials
Hofheinz, F.; Apostolova, I.; Oehme, L.; Kotzerke, J.; van den Hoff, J.;

FDG PET/MR in initial staging of sarcoma: Initial experience and comparison with conventional imaging
Platzek, I.; Beuthien-Baumann, B.; Schramm, G.; Maus, J.; Laniado, M.; Kotzerke, J.; van den Hoff, J.; Schuler, M.;

Studies of carbon monoxide release from ruthenium(II) bipyridine carbonyl complexes upon UV light exposure
Kubeil, M.ORC; Vernooij, R. R.; Kubeil, C.; Wood, B. R.; Graham, B.; Stephan, H.; Spiccia, L.

Expression of ecto-nucleoside triphosphate diphosphohydrolases-2 and -3 by the enteric nervous system impacts inflammation in experimental colitis and Crohn’s disease
Feldbrügge, L.; Moss, A. C.; Yee, E. U.; Csizmadia, E.; Mitsuhashi, S.; Longhi, M. S.; Stephan, H.ORC; Wu, Y.; Cheifetz, A. S.; Müller, C. E.; Sevigny, J.; Robson, S. C.; Jiang, Z. G.

Synthesis and in vitro evaluation of 5-substituted benzovesamicol analogs containing N-substituted amides as potential positron emission tomography tracers for the vesicular acetylcholine transporter
Roslin, S.; de Rosa, M.; Deuther-Conrad, W.; Eriksson, J.; Odell, L. R.; Antoni, G.; Brust, P.; Larhed, M.;

Radiosynthesis of (S)-[18F]T1: The first PET radioligand for molecular imaging of α3β4 nicotinic acetylcholine receptors
Sarasamkan, J.; Fischer, S.; Deuther-Conrad, W.; Ludwig, F.-A.; Scheunemann, M.; Arunrungvichian, K.; Vajragupta, O.; Brust, P.;

Preparation of a novel radiotracer targeting the EphB4 receptor via radiofluorination using spiro azetidinium salts as precursor
Wiemer, J.; Steinbach, J.ORC; Pietzsch, J.ORC; Mamat, C.ORC
  • Journal of Labelled Compounds and Radiopharmaceuticals 60(2017), 489-498
    DOI: 10.1002/jlcr.3526

Surface charge and particle size determine the metabolic fate of dendritic polyglycerols
Pant, K.; Pufe, J.; Zarschler, K.; Bergmann, R.; Steinbach, J.; Reimann, S.; Haag, R.; Pietzsch, J.; Stephan, H.ORC

A novel nanobody-based target module for retargeting of T lymphocytes to EGFR-expressing cancer cells via the modular UniCAR platform
Albert, S.; Arndt, C.; Feldmann, A.; Bergmann, R.; Bachmann, D.; Koristka, S.; Ludwig, F.; Ziller-Walter, P.; Kegler, A.; Gärtner, S.; Schmitz, M.; Ehninger, A.; Cartellieri, M.; Ehninger, G.; Pietzsch, H.-J.; Pietzsch, J.; Steinbach, J.; Bachmann, M.;

A novel tumor pretargeting system based on complementary L-configured oligonucleotides
Schubert, M.; Bergmann, R.; Förster, C.; Sihver, W.; Vonhoff, S.; Klussmann, S.; Bethge, L.; Walther, M.; Schlesinger, J.; Pietzsch, J.; Steinbach, J.; Pietzsch, H.-J.;

X-ray Structures of Succinimidyl Halobenzoates
Mamat, C.; Weiss, D.-H.; Köckerling, M.;

Zwitterionic Modification of Ultra-Small Iron Oxide Nanoparticles for Reduced Protein Corona Formation
Pombo-Garcia, K.; Rühl, C.; Lam, R.; Ang, C.-S.; Scammells, P. J.; Comba, P.; Spiccia, L.; Graham, B.; Joshi, T.; Stephan, H.ORC

Do spiroindolines have the potential to replace vesamicol as lead compound for the development of radioligands targeting the vesicular acetylcholine transporter?
Lindemann, M.; Deuther-Conrad, W.; Moldovan, R.; Sekhar, K. V. G. C.; Brust, P.; Wenzel, B.;

Distribution and kinetics of the Kv1.3-blocking peptide HsTX1[R14A] in experimental rats
Bergmann, R.; Kubeil, M.; Zarschler, K.; Chhabra, S.; Tajhya, R. B.; Beeton, C.; Pennington, M. W.; Bachmann, M.; Norton, R. S.; Stephan, H.ORC

In vivo examination of an injectable hydrogel system crosslinked by peptide-oligosaccharide interaction in immunocompetent nude mice
Tondera, C.; Wieduwild, R.; Röder, E.; Werner, C.; Zhang, Y.; Pietzsch, J.ORC

Development of highly affine and selective fluorinated cannabinoid receptor type 2 ligands
Moldovan, R.-P.; Hausmann, K.; Deuther-Conrad, W.; Brust, P.;

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