Nano-Microsystems for Life Sciences
Healthcare of tomorrow will change dramatically driven by global processes, such as technological advances and the digital revolution. One of the exciting possibilities to establish new patient-care standards relies on the new ultrasensitive diagnostics seamlessly integrated into gadgets, such as point-of-care system, or clinically relevant medical tools to provide maximally personalized assistance and treatment. Our mission is the development of smart miniaturized biosensing devices and systems using nanoscale materials as building blocks and advanced microfluidics to find new routes and parameters that can be employed for the characterization of biomolecules and cells as well as biochemical reactions or processes.
Our interdisciplinary research group is initiated and performed at two institutes: the Institute of Radiopharmaceutical Cancer Research and the Institute of Ion Beam Physics and Materials Research.
Involved departments and internal cooperations:
Projects and support
- ERC Consolidator grant ‘ImmunoChip’
- DFG project: Lab-on-chip systems for multiplexed and multiparametric biochemical assays
- DFG SPP 1726 project: Artificial nanomachines in external potentials
- Else-Kröner-Fresenius Center for Digital Health project: Smart catheters for in-vivo monitoring of blood parameters
- Our group is supported by the High Potential Program at the Helmholtz-Zentrum Dresden-Rossendorf especially by the Institute of Radiopharmaceutical Cancer Research and the Institute of Ion Beam Physics and Materials Research
- DFGGRK 2767: Supracolloidal Structures: From Materials to Optical and Electronic Devices
News & Events
--- 2023 ---
- In Januarys, Deutsche Physikalische Gesellschaft (DPG)s selects Dr. Larysa Baraban as ‚Physikerin der Woche‘ (Female Physisist of the Week). Also check it on social media. Facebook | Instagram | Twitter
Source: A. Wirsig / HZDR
--- 2022 ---
- We wish Dr. Tao Huang all the best! Tao is on the way to China after five successful years spent in our group.
- MDR Sachsen visits our labs to make the video for the news broadcast. Have a look here.
- Group leader Dr. Larysa Baraban receives the prestigious ERC Consolidator Grant from European commission to study cancer immunophenotyping using nanoelectronics. Have a look at our press release.
|Source: HZDR / A. Wirsig|
- We congratulate Diana Isabel Sandoval Bojorquez for receiving the prestigious oral presentation award at European Materials Research Society Fall Meeting 2022. More here.
- Our team contributed to the book ‘Curvilinear Micromagnetism’ with the chapter ‘Curvilinear Magnetic Architectures for Biomedical Engineering’
- Our team contributed to the book ‘Microfluidics and Nanofluidics - Fundamentals and Applications’ with the chapter ‘Real-Time Tracking of Individual Droplets in Multiphase Microfluidics’
- We welcome Ahmed Alsadig from University Trieste as an internship researcher in our group. Ahmed will deal with the development of the surface functionalization of the nanoparticles.
- Our article ' Electrokinetic Janus micromotors moving on topographically flat chemical patterns' by Tao Huang et al., has been accepted in Communications Materials. Congratulations
- Review article 'Real-Time Monitoring of Blood Parameters in the Intensive Care Unit: State-of-the-Art and Perspectives' has been published in Journal of Clinical Medicine.
- Our article ' Multisite Dopamine Sensing With Femtomolar Resolution Using a CMOS Enabled Aptasensor Chip' by V. Seesi and L. Baraban et al., has been published in Frontiers in Neuroscience. Congratulations!
- Congratulations, Xuan Peng, on the Best Poster Award for her poster "Engineering of the alginate capsules for human hepatoma cell (HepG2) encapsulation" at the EMBL conference, Microfluidics 2022.
- Our article "Nanosensors in clinical development of CAR-T cell immunotherapy" by Trang-Anh, Nguyen-Le el. al. has been published in the Biosensors and Bioelectronics journal.
- Tao Huang successfully defended his PhD thesis at TU Dresden, Faculty of Mechanical Science and Engineering. Congratulations!!!
- Xinne Zhao successfully defended her PhD thesis at TU Dresden, Faculty of Mechanical Science and Engineering. Congratulations!!!
--- 2021 ---
- Larysa Baraban acts as co-editor in ChemNanoMat, for the article collection 'Beyond Active Colloids: From Functional Materials to Microscale Robotics’ together with Juliane Simmchen and WeiWang.
- The talk on "OFET biosensors based on stretchable semiconducting polymer: a proof-of-concept application in COVID-19 pandemic" by our PhD Student Trang Anh Nguyen Le won Second Prize for Best Presentation by Young Scientist in NANONET Annual Workshop 2021. Congratulations! (Image credit: Dr. Zahn Peter)
- Our article ‘Rapid Detection of SARS-CoV-2 Antigens and Antibodies Using OFET Biosensors Based on a Soft and Stretchable Semiconducting Polymer’ by Trang Anh Nguyen et al., has been accepted in ACS Biomater Sci Eng. Congratulations!
- Our scientific poster "Highly Sensitive Silicon Nanowire Biosensor Devices for the Investigation of UniCAR Platform in Immunotherapy" submitted to the 8th International Symposium on Sensor Science (I3S Dresden) have won "Best Poster Award to TUD participants". Congratulations!
- Our work 'Coexistence of fluorescent Escherichia coli strains in millifluidic droplet reactors' has been selected as the inner back cover in Lab on a Chip Journal, issue 8, 2021. Check it here!
- We are happy to welcome Dr. Željko Janićijević to join us as PostDoc since 1th of April 2021.
- Our article 'Impact of surface charge on the motion of light-activated Janus micromotors' by Tao Huang, et al., has been accepted in The European Physical Journal E. In this paper, we investigated the dependence of the motility on the ζ-potential of the underlying substrate. The direction of the motion could be inverted by changing the sign of the motor’s zeta potential. The velocity of these micromotors can be further tuned by varying the boundary’s physicochemical properties that they are close to. Congratulations!
- Our article ‘Coexistence of fluorescent Escherichia coli strains in millifluidic droplets reactors’ by Xinne Zhao, Rico Illing et al., has been accepted in Lab-on–a-Chip. Congratulations!
--- 2020 ---
- Our article ‘Electrochemical detection of ascorbic acid in artificial sweat using flexible alginate/CuO modified electrode‘ has been accepted in Microchimica Acta.
- Our article 'Nanocytometer for smart analysis of peripheral blood and acute myeloid leukemia: a pilot study' by Julian Schütt, Diana Sandoval Bojorquez et al., has been accepted in Nano Letters. Congratulations!
- Manuscript of Tao Huang et al. on the study of the inverse solidification induced by active particles are highlighted with a front cover page in Advanced Functional Materials. (to wait until publishing)
- We are happy to welcome Dr. Marvin Barahona to join us as PostDoc since 1th of August 2020. He will focus on the development of the in-vivo sensors integrated onto the surface of catheters and the development of electronic platforms for monitoring of biological signals.
- Our article ‘Inverse solidification induced by active Janus particle‘ by Tao Huang et al., has been accepted for publication in Advanced Functional Materials. Congratulations Tao!
- Our paper of Tao Huang et al. on the study of the exclusion behavior in active soft matter systems is highlighted with a cover page of Langmuir. This work is part of the Special Issue on Advances in Active Materials. T. Huang, S. Gobeil, X. Wang, V. Misko, F. Nori, W. De Malsche, J. Fassbender, D. Makarov, G. Cuniberti, and L. Baraban 'Anisotropic exclusion effect between photocatalytic Ag/AgCl Janus particles and passive beads in a dense colloidal matrix' Langmuir 36, 7091 (2020).
- Our article ‘Intrinsic plasticity of silicon nanowire neurotransistors for dynamic memory and learning functions‘ is highlighted in multiple news outlets (see summary below): https://www.nature.com/articles/s41928-020-0412-1/metrics
- Our article ‘Intrinsic plasticity of silicon nanowire neurotransistors for dynamic memory and learning functions‘ by Eunhye Baek et al., has been published in Nature Electronics. Congratulations Eunhye! Baek, E., Das, N.R., Cannistraci, C.V. et al. Intrinsic plasticity of silicon nanowire neurotransistors for dynamic memory and learning functions. Nat Electron (2020). https://doi.org/10.1038/s41928-020-0412-1