Bioanorganische Chemie und Pathobiochemie (Chem-Ma-B01)
Lecturers |
Prof. Dr. Jens Pietzsch (Lecturer in charge) Dr. Manja Kubeil, Dr. Markus Laube, Dr. Sandra Hauser, Dr. Martin Ullrich |
Information on the courses |
The module Chem-Ma-B01 is offered in the teacher training programs GY and BS as module MN-SEGY-CHE-20F or MN-SEBS-CHE-20F. The lecture Pathobiochemistry/Medical Biochemistry II is offered as part of the module Chem-Ma-TB07 of the consecutive Master's program in Biochemistry. The next lectures will be offered in English from the winter semester 2025/2026. If you are interested in internship semesters/master theses, please have a look at here. |
Location/Time |
Seminar room CHE/153 The lecture takes place weekly on Wednesdays in the 4th double lesson (1.00 pm to 2.30 pm; s.t. - Bioinorganic Chemistry) and in the 5th double lesson (2.50 pm to 4.20 pm; s.t. - Pathobiochemistry/Medical Biochemistry II). Bioinorganic Chemistry: lecture finished Pathobiochemistry/Medicinal Biochemistry II: lecture finished Seminar: finished Please also refer to the corresponding entries in OPAL and SELMA. |
Online | In the case of an online lecture, the dial-in modalities (link (Zoom/BBB)) will be announced here accordingly. |
Content |
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Exams |
Modules Chem-Ma-B01 / MN-SEGY-CHE-20F / MN-SEBS-CHE-20F Oral examination (individual examination, 60 min): Dates will be arranged individually 28.03. at HZDR, Building 805, Room 265 The oral examination can be taken in German or English. Module Chem-Ma-TB07 Written exam: Date will be announced in time The exam language is English. |
Links |
To prepare for the lecture Bioinorganic Chemistry, please use the lecture notes (scripts see below). *** To prepare for the lecture Pathobiochemistry/Medical Biochemistry II, please use the lecture notes and the reading material for self-study (Skript). For both lectures, please also recapitulate the contents of previous chemistry and biochemistry lectures, especially on
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Course of the academic year
Pathobiochemistry schedule
- Introduction to pathobiochemistry
- General and special pathobiochemistry
- Signal transduction
- Inflammation
- Inflammatory diseases
- Atherogenesis
- Diseases of the lipoprotein metabolism
- Metabolic syndrome
- Inflammogenesis of tumors
Bioinorganic Chemistry schedule
Thema | |
L1 - Overview Bioinorganic chemistry, trace elements, bioligands |
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L2 - Basic Principles of Coordination Chemistry |
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L3 - Alkaline metals (sodium, potassium) Recognition of spherical species, membrane pumps and channels |
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L4 - Alkaline earth metals (calcium, magnesium) Biomineralization, messenger substances and structure formers |
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L5 - Zinc, Copper enzymatic catalysis, regulatory functions |
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L6 - Manganese, Cobalt, Nickel Photosynthesis, Cobalamines, Nickel - a long overlooked biometal |
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L7 - Iron Oxygen transport, Heme-Fe and None-heme-Fe |
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L8 - Molybdenum, Vanadium, Chromium, Tungsten Nitrogen fixation, Haloperoxidases, Cr(III) - role in humans? |
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L9 - Gasotransmitters NO, CO, H2S Biosynthesis, reactive oxygen and nitrogen species |
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L10 - Toxic metals Pb, Hg, Cd, As, Chelate therapy |
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L11 - Inorganic drugs Diagnostics and therapeutics |
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L12 - Radioactive metals in the environment and medicine natural and artificial radioisotopes |
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L13 - Seminar |