Publikationen - Institut für Radiopharmazeutische Krebsforschung
103 Publikationen2024
RevCAR-expressing immune effector cells for targeting of Fn14-positive glioblastoma
Abdelfatah Saleh Hassan, H. A.; Mitwasi, N.; Rodrigues Loureiro, L. R.; Kegler, A.; Elizabeth González Soto, K.; Hoffmann, L.; Crespo, E.; Arndt, C.; Bergmann, R.; Bachmann, M.; Feldmann, A.
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Cancer Gene Therapy (2024)
Online First (2024) DOI: 10.1038/s41417-024-00766-8
Impact of Viscosity on Human Hepatoma Spheroids in Soft Core-Shell Microcapsules
Peng, X.; Janićijević, Ž.; Lemm, S.; Hauser, S.; Knobel, M.; Pietzsch, J.; Bachmann, M.; Baraban, L.
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Advanced Healthcare Materials (2024), 2302609
Online First (2024) DOI: 10.1002/adhm.202302609
Bone marrow-derived mesenchymal stromal cells obstruct AML-targeting CD8+ clonal effector and CAR T cell function while promoting a senescence-associated phenotype
Towers, R.; Trombello, L.; Fusenig, M.; Tunger, A.; Baumann, A.-L.; Savoldelli, R.; Wehner, R.; Fasslrinner, F.; Arndt, C.; Dazzi, F.; von Bonin, M.; Feldmann, A.; Bachmann, M.; Wobus, M.; Schmitz, M.; Bornhäuser, M.
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Cancer Immunology, Immunotherapy 73(2024), 8
DOI: 10.1007/s00262-023-03594-1
Portable Droplet-Based Real-Time Monitoring of Pancreatic α-Amylase in Postoperative Patients
Zhao, X.; Kolbinger, F. R.; Distler, M.; Weitz, J.; Makarov, D.; Bachmann, M.; Baraban, L.
Verknüpfte Publikationen
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Data publication: Portable Droplet-Based Real-Time Monitoring of Pancreatic …
ROBIS: 38005 HZDR-primary research data are used by this (Id 38002) publication
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Biosensors and Bioelectronics 251(2024), 116034
Online First (2024) DOI: 10.1016/j.bios.2024.116034 -
WWW-Beitrag
https://www.researchsquare.com/article/rs-2800086/v1
DOI: 10.21203/rs.3.rs-2800086/v1
Shell engineering in soft alginate-based capsules for culturing liver spheroids
Peng, X.; Janićijević, Ž.; Lemm, S.; Laube, M.; Pietzsch, J.; Bachmann, M.; Baraban, L.
Verknüpfte Publikationen
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Data publication: Shell engineering in soft alginate-based capsules for …
ROBIS: 35501 HZDR-primary research data are used by this (Id 35494) publication
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Biotechnology Journal (2024)
Online First (2022) DOI: 10.22541/au.165830418.86011497/v1
2023
Molecular imaging of bacterial outer membrane vesicles based on bacterial surface display
Szöllősi, D.; Hajdrik, P.; Tordai, H.; Horváth, I.; Veres, D. S.; Gillich, B.; Das Shailaja, K.; Smeller, L.; Bergmann, R.; Bachmann, M.; Mihály, J.; Gaál, A.; Jezsó, B.; Barátki, B.; Kövesdi, D.; Bősze, S.; Szabó, I.; Felföldi, T.; Oszwald, E.; Padmanabhan, P.; Zoltán Gulyás, B.; Hamdani, N.; Máthé, D.; Varga, Z.; Szigeti, K.
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Scientific Reports 13(2023), 18752
DOI: 10.1038/s41598-023-45628-9
Cited 2 times in Scopus
Targeting colorectal cancer cells using AND-gated Adaptor RevCAR T-cells
González Soto, K. E.; Rodrigues Loureiro, L. R.; Bartsch, T.; Arndt, C.; Kegler, A.; Mitwasi, N.; Drewitz, L.; Hoffmann, L.; Abdelfatah Saleh Hassan, H. A.; Crespo, E.; Mehnert, M.; Daglar, C.; Abken, H.; Momburg, F.; Bachmann, M.; Feldmann, A.
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Frontiers in Immunology 14(2023), 1302354
DOI: 10.3389/fimmu.2023.1302354
Cited 1 times in Scopus
Methods gold standard in clinic millifluidics multiplexed extended gate field-effect transistor biosensor with gold nanoantennae as signal amplifiers
Janićijević, Ž.; Nguyen Le, T. A.; Alsadig, A.; Cela, I.; Zilenaite, R.; Tonmoy, T. H.; Kubeil, M.; Bachmann, M.; Baraban, L.
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Biosensors and Bioelectronics 241(2023), 115701
Online First (2023) DOI: 10.1016/j.bios.2023.115701
Cited 1 times in Scopus
Immunotheranostic target modules for imaging and navigation of UniCAR T-cells to strike FAP-expressing cells and the tumor microenvironment
Rodrigues Loureiro, L. R.; Hoffmann, L.; Neuber, C.; Rupp, L.; Arndt, C.; Kegler, A.; Kubeil, M.; Hagemeyer, C. E.; Stephan, H.; Schmitz, M.; Feldmann, A.; Bachmann, M.
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Journal of Experimental & Clinical Cancer Research 42(2023), 341
Online First (2023) DOI: 10.1186/s13046-023-02912-w
Cited 1 times in Scopus
Exploring the Potential of Nanogels: From Drug Carriers to Radiopharmaceutical Agents
Kubeil, M.; Suzuki, Y.; Casulli, M. A.; Kamal, R.; Hashimoto, T.; Bachmann, M.; Hayashita, T.; Stephan, H.
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Advanced Healthcare Materials 13(2023)1, 2301404
Online First (2023) DOI: 10.1002/adhm.202301404
Cited 1 times in Scopus
Bispidine Chelators for Radiopharmaceutical Applications with Lanthanide, Actinide and Main Group Metal Ions
Kopp, I.; Cieslik, P.; Anger, K.; Josephy, T.; Neupert, L.; Velmurugan, G.; Gast, M.; Wadepohl, H.; Brühlmann, S. A.; Walther, M.; Kopka, K.; Bachmann, M.; Stephan, H.; Kubeil, M.; Comba, P.
Verknüpfte Publikationen
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Data publication: Bispidine Chelators for Radiopharmaceutical Applications …
ROBIS: 37587 HZDR-primary research data are used by this (Id 37460) publication
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Inorganic Chemistry 62(2023)50, 20754-20768
Online First (2023) DOI: 10.1021/acs.inorgchem.3c02340
Cited 2 times in Scopus
A novel ACE2 decoy for both neutralization of SARS-CoV-2 variants and killing of infected cells
Kegler, A.; Drewitz, L.; Arndt, C.; Daglar, C.; Rodrigues Loureiro, L. R.; Mitwasi, N.; Neuber, C.; González Soto, K. E.; Bartsch, T.; Baraban, L.; Ziehr, H.; Heine, M.; Nieter, A.; Moreira-Soto, A.; Kühne, A.; Drexler, J. F.; Seliger, B.; Laube, M.; Máthé, D.; Pályi, B.; Hajdrik, P.; Forgách, L.; Kis, Z.; Szigeti, K.; Bergmann, R.; Feldmann, A.; Bachmann, M.
Beteiligte Forschungsanlagen
- ZRT
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Frontiers in Immunology 14(2023), 1204543
DOI: 10.3389/fimmu.2023.1204543
Cited 1 times in Scopus
FLT3-directed UniCAR T-cell therapy of Acute Myeloid Leukaemia
Peschke, J.; Bergmann, R.; Mehnert, M.; González Soto, K. E.; Rodrigues Loureiro, L. R.; Mitwasi, N.; Kegler, A.; Altmann, H.; Wobus, M.; Máthé, D.; Szigeti, K.; Feldmann, A.; Bornhäuser, M.; Bachmann, M.; Fasslrinner, F.; Arndt, C.
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British Journal of Haematology 202(2023)6, 1137-1150
DOI: 10.1111/bjh.18971
Cited 1 times in Scopus
Preclinical Characterization of the 177Lu-Labeled Prostate Stem Cell Antigen (PSCA)-Specific Monoclonal Antibody 7F5
Striese, F.; Neuber, C.; Gräßel, S.; Arndt, C.; Ullrich, M.; Steinbach, J.; Pietzsch, J.; Bergmann, R.; Pietzsch, H.-J.; Sihver, W.; Frenz, M.; Feldmann, A.; Bachmann, M.
Beteiligte Forschungsanlagen
- PET-Zentrum
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International Journal of Molecular Sciences 24(2023)11, 9420
DOI: 10.3390/ijms24119420
Cited 2 times in Scopus
Multivalent adaptor proteins specifically target NK cells carrying a universal chimeric antigen receptor to ErbB2 (HER2)-expressing cancers
Pfeifer Serrahima, J.; Zhang, C.; Oberoi, P.; Bodden, M.; Röder, J.; Arndt, C.; Feldmann, A.; Kiefer, A.; Prüfer, M.; Kühnel, I.; Tonn, T.; Bachmann, M.; Wels, W. S.
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Cancer Immunology, Immunotherapy 72(2023), 2905-2918
DOI: 10.1007/s00262-023-03374-x
Cited 4 times in Scopus
Specific and safe targeting of glioblastoma using switchable and logic-gated RevCAR T cells
Abdelfatah Saleh Hassan, H. A.; Mitwasi, N.; Ullrich, M.; Kubeil, M.; Toussaint, M.; Deuther-Conrad, W.; Neuber, C.; Arndt, C.; Rodrigues Loureiro, L. R.; Kegler, A.; González Soto, K. E.; Belter, B.; Rössig, C.; Pietzsch, J.; Frenz, M.; Bachmann, M.; Feldmann, A.
Beteiligte Forschungsanlagen
- PET-Zentrum
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Frontiers in Immunology 14(2023), 1166169
DOI: 10.3389/fimmu.2023.1166169
Cited 5 times in Scopus
Immunotargeting of Cancer Stem Cells.
Köseer, A. S.; Di Gaetano, S.; Arndt, C.; Bachmann, M.; Dubrovska, A.
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Cancers 15(2023), 1608
Online First (2023) DOI: 10.3390/cancers15051608
Cited 3 times in Scopus
High-Throughput Gel Microbeads as Incubators for Bacterial Competition Study
Nguyen Le, T. A.; Zhao, X.; Bachmann, M.; Ruelens, P.; de Visser, J. A. G. M.; Baraban, L.
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Micromachines 14(2023), 645
DOI: 10.3390/mi14030645
Cited 2 times in Scopus
Impedimetric Nanobiosensor for the Detection of SARS-CoV-2 Antigens and Antibodies
Sandoval Bojorquez, D. I.; Janićijević, Ž.; Palestina Romero, B.; Oliveros Mata, E. S.; Laube, M.; Feldmann, A.; Kegler, A.; Drewitz, L.; Fowley, C.; Pietzsch, J.; Faßbender, J.; Tonn, T.; Bachmann, M.; Baraban, L.
Verknüpfte Publikationen
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Data publication: Impedimetric Nanobiosensor for the Detection of SARS-CoV-2 …
ROBIS: 36555 HZDR-primary research data are used by this (Id 36553) publication
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ACS Sensors 8(2023)2, 576-586
Online First (2023) DOI: 10.1021/acssensors.2c01686
Cited 8 times in Scopus
Enzymological characterization of ⁶⁴Cu-labeled neprilysin substrates and their application for modulating the renal clearance of targeted radiopharmaceuticals
Brandt, F.; Ullrich, M.; Wodtke, J.; Kopka, K.; Bachmann, M.; Löser, R.; Pietzsch, J.; Pietzsch, H.-J.; Wodtke, R.
Beteiligte Forschungsanlagen
- ZRT
Verknüpfte Publikationen
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Data to NEP paper
ROBIS: 35827 HZDR-primary research data are used by this (Id 35120) publication -
Data to NEP paper
RODARE: 2027 HZDR-primary research data are used by this (Id 35120) publication
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Journal of Medicinal Chemistry 66(2023)1, 516-537
Online First (2023) DOI: 10.1021/acs.jmedchem.2c01472
Cited 7 times in Scopus
Palbociclib impairs the proliferative capacity of activated T cells while retaining their cytotoxic efficacy
Arndt, C.; Tunger, A.; Wehner, R.; Rothe, R.; Kourtellari, E.; Luttosch, S.; Hannemann, K.; Koristka, S.; Loureiro, L. R.; Feldmann, A.; Tonn, T.; Link, T.; Kuhlmann, J. D.; Wimberger, P.; Bachmann, M.; Schmitz, M.
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Frontiers in Pharmacology 14(2023), 970457
DOI: 10.3389/fphar.2023.970457
Cited 3 times in Scopus
2022
Clinical Significance of Tumor-Infiltrating Conventional and Plasmacytoid Dendritic Cells in Pancreatic Ductal Adenocarcinoma
Plesca, I.; Benešová, I.; Beer, C.; Sommer, U.; Müller, L.; Wehner, R.; Heiduk, M.; Aust, D.; Baretton, G.; Bachmann, M.; Feldmann, A.; Weitz, J.; Seifert, L.; Seifert, A. M.; Schmitz, M.
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Cancers 14(2022), 1216
DOI: 10.3390/cancers14051216
Cited 12 times in Scopus
Induction of pulmonary HLA-G expression by SARS-CoV-2 infection
Seliger, B.; Jasinski-Bergner, S.; Masssa, C.; Müller, A.; Biehl, K.; Yang, B.; Bachmann, M.; Jonigk, D.; Eichhorn, P.; Hartmann, A.; Wickenhauser, C.; Bauer, M.
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Cellular and Molecular Life Sciences 79(2022)11, 582
DOI: 10.1007/s00018-022-04592-9
Cited 7 times in Scopus
Towards personalized medicine: one chelator for imaging and therapy with lutetium-177 and actinium-225
Cieslik, P.; Kubeil, M.; Zarschler, K.; Ullrich, M.; Brandt, F.; Anger, K.; Wadepohl, H.; Kopka, K.; Bachmann, M.; Pietzsch, J.; Stephan, H.; Comba, P.
Beteiligte Forschungsanlagen
- ZRT
Verknüpfte Publikationen
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Data publication: One chelator for imaging and therapy with lutetium-177 and …
ROBIS: 35458 HZDR-primary research data are used by this (Id 35394) publication
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Journal of the American Chemical Society 144(2022)47, 21555-21567
Online First (2022) DOI: 10.1021/jacs.2c08438
Cited 10 times in Scopus
Nanochips assisted peptide screening for clinical development of CAR-T cell immunotherapy
Anh Nguyen-Le, T.; Bartsch, T.; Wodtke, R.; Brandt, F.; Arndt, C.; Feldmann, A.; Isabel Sandoval Bojorquez, D.; Perez Roig, A.; Ibarlucea, B.; Lee, S.; Baek, C.-K.; Cuniberti, G.; Bergmann, R.; Puentes-Cala, E.; Andrés Soto, J.; T. Kurien, B.; Bachmann, M.; Baraban, L.
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Biosensors and Bioelectronics 206(2022), 114124
Online First (2022) DOI: 10.1016/j.bios.2022.114124
Cited 5 times in Scopus
Combining Radiation- with Immunotherapy in Prostate Cancer: Influence of Radiation on T cells
Lindner, D.; Arndt, C.; Loureiro, L. R.; Feldmann, A.; Kegler, A.; Koristka, S.; Berndt, N.; Mitwasi, N.; Bergmann, R.; Frenz, M.; Bachmann, M.
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International Journal of Molecular Sciences 23(2022)14, 7922
DOI: 10.3390/ijms23147922
Cited 2 times in Scopus
Targeting CD10 on B-Cell Leukemia Using the Universal CAR T-Cell Platform (UniCAR)
Mitwasi, N.; Arndt, C.; Loureiro, L. R.; Kegler, A.; Fasslrinner, F.; Berndt, N.; Bergmann, R.; HoˇRejší, V.; Rössig, C.; Bachmann, M.; Feldmann, A.
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International Journal of Molecular Sciences 23(2022)9, 4920
Online First (2022) DOI: 10.3390/ijms23094920
Cited 3 times in Scopus
Development and functional characterization of a versatile radio-/immunotheranostic tool for prostate cancer management
Arndt, C.; Bergmann, R.; Striese, F.; Merkel, K.; Máthé, D.; Loureiro, L. R.; Mitwasi, N.; Kegler, A.; Fasslrinner, F.; González Soto, K. E.; Neuber, C.; Berndt, N.; Kovács, N.; Szöllősi, D.; Hegedűs, N.; Tóth, G.; Emmermann, J.-P.; Harikumar, K. B.; Kovacs, T.; Bachmann, M.; Feldmann, A.
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Cancers 14(2022)8, 1996
DOI: 10.3390/cancers14081996
Cited 9 times in Scopus
Validation of CD98hc as a therapeutic target for a combination of radiation and immunotherapies in head and neck squamous cell carcinoma
Köseer, A. S.; Loureiro, L. R.; Jureczek, J.; Mitwasi, N.; González Soto, K. E.; Aepler, J.; Bartsch, T.; Feldmann, A.; Kunz-Schughart, L. A.; Linge, A.; Krause, M.; Bachmann, M.; Arndt, C.; Dubrovska, A.
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Cancers 14(2022)7, 1677
DOI: 10.3390/cancers14071677
Cited 8 times in Scopus
Dual-Labelling Strategies for Nuclear and Fluorescence Molecular Imaging: Current Status and Future Perspectives
Kubeil, M.; Santana Martinez, I. I.; Bachmann, M.; Kopka, K.; Tuck L., K.; Stephan, H.
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Pharmaceuticals 15(2022), 432
DOI: 10.3390/ph15040432
Cited 8 times in Scopus
Structure-Based Design, Optimization and Development of [18F]LU13, a novel radioligand for CB2R Imaging in the Brain with PET
Gündel, D.; Deuther-Conrad, W.; Ueberham, L.; Kaur, S.; Otikova, E.; Teodoro, R.; Lai, T. H.; Clauß, O.; Scheunemann, M.; Bormans, G.; Bachmann, M.; Kopka, K.; Brust, P.; Moldovan, R.-P.
Verknüpfte Publikationen
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Data Publication: Structure-Based Design, Optimization and Development of …
ROBIS: 34030 HZDR-primary research data are used by this (Id 33987) publication
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Journal of Medicinal Chemistry 65(2022)13, 9034-9049
Online First (2022) DOI: 10.1021/acs.jmedchem.2c00256
Cited 9 times in Scopus
“Clickable” albumin binders for modulating the tumor uptake of targeted radiopharmaceuticals
Brandt, F.; Ullrich, M.; Laube, M.; Kopka, K.; Bachmann, M.; Löser, R.; Pietzsch, J.; Pietzsch, H.-J.; van den Hoff, J.; Wodtke, R.
Beteiligte Forschungsanlagen
- PET-Zentrum
Verknüpfte Publikationen
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Data Alb/SSTR2 ligands
ROBIS: 33631 HZDR-primary research data are used by this (Id 33477) publication
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Journal of Medicinal Chemistry 66(2022)1, 710-733
Online First (2021) DOI: 10.1021/acs.jmedchem.1c01791
Cited 15 times in Scopus
2021
Rapid Detection of SARS-CoV-2 Antigens and Antibodies Using OFET Biosensors Based on a Soft and Stretchable Semiconducting Polymer
Ditte, K.; Nguyen Le, T. A.; Ditzer, O.; Isabel Sandoval Bojorquez, D.; Chae, S.; Bachmann, M.; Baraban, L.; Lissel, F.
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ACS Biomaterials Science & Engineering (2021)
Online First (2021) DOI: 10.1021/acsbiomaterials.1c00727
Cited 34 times in Scopus
A Small Step, a Giant Leap: Somatic Hypermutation of a Single Amino Acid Leads to Anti-La Autoreactivity
Bartsch, T.; Arndt, C.; Loureiro, L. R.; Kegler, A.; Puentes-Cala, E.; Soto, J. A.; Kurien, B. T.; Feldmann, A.; Berndt, N.; Bachmann, M.
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International Journal of Molecular Sciences 22(2021)21, 12046
Online First (2021) DOI: 10.3390/ijms222112046
Cited 1 times in Scopus
Targeting acute myeloid leukemia using the RevCAR platform: a programmable, switchable and combinatorial strategy
Kittel-Boselli, E.; González Soto, K. E.; Loureiro, L. R.; Hoffmann, A.; Bergmann, R.; Arndt, C.; Koristka, S.; Mitwasi, N.; Kegler, A.; Bartsch, T.; Berndt, N.; Altmann, H.; Fasslrinner, F.; Bornhäuser, M.; Bachmann, M.; Feldmann, A.
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Cancers 13(2021)19, 4785
DOI: 10.3390/cancers13194785
Cited 16 times in Scopus
And yet it moves: Oxidation of the Nuclear Autoantigen La/SS-B is the Driving Force for Nucleo-Cytoplasmic Shuttling
Berndt, N.; Bippes, C. C.; Michalk, I.; Bartsch, T.; Arndt, C.; Puentes-Cala, E.; Soto, J. A.; Loureiro, L. R.; Kegler, A.; Bachmann, D.; Gross, J. K.; Gross, T.; Kurien, B.; Scofield, T. R. H.; Farris, A. D.; James, J. A.; Bergmann, R.; Schmitz, M.; Feldmann, A.; Bachmann, M.
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International Journal of Molecular Sciences 22(2021)18, 9699
Online First (2021) DOI: 10.3390/ijms22189699
Cited 7 times in Scopus
Coexistence of fluorescent Escherichia coli strains in millifluidic droplet reactors
Zhao, X.; Illing, R.; Ruelens, P.; Bachmann, M.; Cuniberti, G.; de Visser, J. A. G. M.; Baraban, L.
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Lab on a chip 21(2021), 1492-1502
DOI: 10.1039/D0LC01204A
Cited 6 times in Scopus
Two Be or Not Two Be: The Nuclear Autoantigen La/SS-B Is able to form Dimers and Oligomers in a Redox Dependent Manner
Berndt, N.; Bippes, C. C.; Michalk, I.; Bachmann, D.; Bachmann, J.; Puentes-Cala, E.; Bartsch, T.; Loureiro, L. R.; Kegler, A.; Bergmann, R.; Gross, J. K.; Gross, T.; Kurien, B. T.; Scofield, R. H.; Farris, A. D.; James, J. A.; Schmitz, M.; Fahmy, K.; Feldmann, A.; Arndt, C.; Bachmann, M.
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International Journal of Molecular Sciences 22(2021)7, 3377
DOI: 10.3390/ijms22073377
Cited 6 times in Scopus
Development of a ghrelin receptor inverse agonist for positron emission tomography
Bergmann, R.; Chollet, C.; Els-Heindl, S.; Ullrich, M.; Berndt, N.; Pietzsch, J.; MáThé, D.; Bachmann, M.; Beck-Sickinger, A. G.
Beteiligte Forschungsanlagen
- PET-Zentrum
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Oncotarget 12(2021)5, 33747360
DOI: 10.18632/oncotarget.27895
Cited 3 times in Scopus
T Cell Mediated Conversion of a Non-anti-La Reactive B cell to an Autoreactive anti-La B Cell by Somatic Hypermutation
Bachmann, M.; Bartsch, T.; Bippes, C. C.; Bachmann, D.; Puentes-Cala, E.; Bachmann, J.; Bartsch, H.; Arndt, C.; Koristka, S.; Loureiro, L. R.; Kegler, A.; Laube, M.; Gross, J. K.; Gross, T.; Kurien, B.; Scofield, R. H.; Farris, A. D.; James, J. A.; Schmitz, M.; Feldmann, A.
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International Journal of Molecular Sciences 22(2021)3, 1198
DOI: 10.3390/ijms22031198
Cited 9 times in Scopus
HIF2alpha-associated pseudohypoxia promotes radioresistance in pheochromocytoma: insights from 3D models
Seifert, V.; Richter, S.; Bechmann, N.; Bachmann, M.; Ziegler, C. G.; Pietzsch, J.; Ullrich, M.
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Cancers 13(2021), 385
DOI: 10.3390/cancers13030385
Cited 12 times in Scopus
Highly sensitive silicon nanowire biosensor devices for the investigation of UniCAR platform in immunotherapy
Nguyen Le, T. A.; Sandoval Bojorquez, D. I.; Arnau, P. R.; Bergoi, I.; Feldmann, A.; Gianaurelio, C.; Bachmann, M.; Baraban, L.
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Engineering Proceedings 6(2021)1, 20
Online First (2021) DOI: 10.3390/I3S2021Dresden-10109
2020
Nanocytometer for smart analysis of peripheral blood and acute myeloid leukemia: a pilot study
Schütt, J.; Sandoval Bojorquez, D. I.; Avitabile, E.; Oliveros Mata, E. S.; Milyukov, G.; Colditz, J.; Delogu, L. G.; Rauner, M.; Feldmann, A.; Koristka, S.; Middeke, J. M.; Sockel, K.; Faßbender, J.; Bachmann, M.; Bornhäuser, M.; Cuniberti, G.; Baraban, L.
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Nano Letters 20(2020)9, 6572-6581
DOI: 10.1021/acs.nanolett.0c02300
Cited 12 times in Scopus
Rapidly Switchable Universal CAR-T Cells for Treatment of CD123-Positive Leukemia
Loff, S.; Dietrich, J.; Meyer, J.-E.; Riewaldt, J.; Spehr, J.; von Bonin, M.; Gründer, C.; Swayampakula, M.; Franke, K.; Feldmann, A.; Bachmann, M.; Ehninger, G.; Ehninger, A.; Cartellieri, M.
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Molecular Therapy Oncolytics 17(2020), 408-420
DOI: 10.1016/j.omto.2020.04.009
Cited 59 times in Scopus
Versatile chimeric antigen receptor platform for controllable and combinatorial T cell therapy
Feldmann, A.; Hoffmann, A.; Bergmann, R.; Koristka, S.; Berndt, N.; Arndt, C.; Loureiro, L. R.; Kittel-Boselli, E.; Mitwasi, N.; Kegler, A.; Lamprecht, C.; González Soto, K. E.; Bachmann, M.
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OncoImmunology 9(2020)1, 1785608
DOI: 10.1080/2162402X.2020.1785608
Cited 40 times in Scopus
Adaptor CAR platforms - next generation of T cell-based cancer immunotherapy
Arndt, C.; Fasslrinner, F.; Loureiro, L. R.; Koristka, S.; Feldmann, A.; Bachmann, M.
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Cancers 12(2020)5, 1302
DOI: 10.3390/cancers12051302
Cited 44 times in Scopus
Highly efficient targeting of EGFR-expressing tumor cells with UniCAR T cells via target modules based on Cetuximab®
Jureczek, J.; Feldmann, A.; Bergmann, R.; Arndt, C.; Berndt, N.; Koristka, S.; Loureiro, L. R.; Mitwasi, N.; Hoffmann, A.; Kegler, A.; Bartsch, T.; Bachmann, M.
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OncoTargets and Therapy 13(2020), 5515-5527
DOI: 10.2147/OTT.S245169
Cited 17 times in Scopus
Extended half-life target module for sustainable UniCAR T-cell treatment of STn-expressing cancers
Loureiro, L. R.; Feldmann, A.; Bergmann, R.; Koristka, S.; Berndt, N.; Máthé, D.; Hegedüs, N.; Szigeti, K.; Videira, P. A.; Bachmann, M.; Arndt, C.
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Journal of Experimental & Clinical Cancer Research 39(2020), 77
DOI: 10.1186/s13046-020-01572-4
Cited 25 times in Scopus
UniCAR T cell immunotherapy enables efficient elimination of radioresistant cancer cells
Arndt, C.; Loureiro, L. R.; Feldmann, A.; Jureczek, J.; Bergmann, R.; Máthé, D.; Hegedüs, N.; Berndt, N.; Koristka, S.; Metwasi, N.; Fasslrinner, F.; Lamprecht, C.; Kegler, A.; Hoffmann, A.; Bartsch, T.; Köseer, A. S.; Egan, G.; Schmitz, M.; Hořejší, V.; Krause, M.; Dubrovska, A.; Bachmann, M.
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OncoImmunology 9(2020)1, 1743036
DOI: 10.1080/2162402X.2020.1743036
Cited 25 times in Scopus
The sigma-1 receptor: potential role in the modulation of cellular radiation sensitivity
Belter, B.; Deuther-Conrad, W.; Hofheinz, F.; Bachmann, M.; Brust, P.; Pietzsch, J.
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Journal of Cellular Biotechnology 6(2020), 13-21
DOI: 10.3233/JCB-209007
“UniCAR”-modified off-the-shelf NK-92 cells for targeting of GD2-expressing tumour cells
Mitwasi, N.; Feldmann, A.; Arndt, C.; Koristka, S.; Berndt, N.; Jureczek, J.; Loureiro, L.; Bergmann, R.; Máthé, D.; Hegedüs, N.; Kovács, T.; Zhang, C.; Oberoi, P.; Jäger, E.; Seliger, B.; Rössig, C.; Temme, A.; Eitler, J.; Tonn, T.; Schmitz, M.; Hassel, J.; Jäger, D.; Wels, W.; Bachmann, M.
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Scientific Reports 10(2020), 2141
DOI: 10.1038/s41598-020-59082-4
Cited 63 times in Scopus
Radioimmunotherapy in Combination with Reduced-Intensity Conditioning for Allogeneic Hematopoietic Cell Transplantation in Patients with Advanced Multiple Myeloma
Fasslrinner, F.; Stölzel, F.; Kramer, M.; Teipel, R.; Brogsitter, C.; Morgner, A.; Arndt, C.; Bachmann, M.; Hänel, M.; Röllig, C.; Kotzerke, J.; Schetelig, J.; Bornhäuser, M.
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Biology of Blood and Marrow Transplantation 26(2020)4, 691-697
Online First (2019) DOI: 10.1016/j.bbmt.2019.11.007
Cited 6 times in Scopus
Versatile Bispidine-based Bifunctional Chelators for 64CuII-Labelling of Biomolecules
Singh, G.; Zarschler, K.; Hunoldt, S.; Santana Martinez, I. I.; Rühl, C.; Matterna, M.; Bergmann, R.; Mathe, D.; Hegedüs, N.; Bachmann, M.; Comba, P.; Stephan, H.
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Chemistry - A European Journal 26(2020), 1989-2001
Online First (2020) DOI: 10.1002/chem.201904654
Cited 23 times in Scopus
2019
The Evolving Landscape of Biomarkers for Anti-PD-1 or Anti-PD-L1 Therapy
Tunger, A.; Sommer, U.; Wehner, R.; Kubasch, A. S.; Grimm, M.-O.; Bachmann, M.; Platzbecker, U.; Bornhaeuser, M.; Baretton, G.; Schmitz, M.
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Journal of Clinical Medicine 8(2019)10, 1534
DOI: 10.3390/jcm8101534
Cited 38 times in Scopus
Conventional CARs versus modular CARs
Feldmann, A.; Arndt, C.; Koristka, S.; Berndt, N.; Bergmann, R.; Bachmann, M.
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Cancer Immunology, Immunotherapy 68(2019)10, 1713-1719
DOI: 10.1007/s00262-019-02399-5
Cited 35 times in Scopus
A theranostic PSMA ligand for PET imaging and retargeting of T cells expressing the universal chimeric antigen receptor UniCAR
Arndt, C.; Feldmann, A.; Koristka, S.; Schäfer, M.; Bergmann, R.; Metwasi, N.; Berndt, N.; Bachmann, D.; Kegler, A.; Schmitz, M.; Puentes-Cala, E.; Soto, J. A.; Ehninger, G.; Pietzsch, J.; Liolios, C.; Wunderlich, G.; Kotzerke, J.; Kopka, K.; Bachmann, M.
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OncoImmunology 8(2019)9, 1659095
Online First (2019) DOI: 10.1080/2162402X.2019.1659095
Cited 23 times in Scopus
Theranostic CAR T cell targeting: A brief review
Arndt, C.; Bachmann, M.; Bergmann, R.; Berndt, N.; Feldmann, A.; Koristka, S.
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Journal of Labelled Compounds and Radiopharmaceuticals 62(2019)8, 533-540
DOI: 10.1002/jlcr.3727
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Instant kit preparation of 68Ga-radiopharmaceuticals via the hybrid chelator DATA: clinical translation of [68Ga]Ga-DATA-TOC
Sinnes, J. P.; Nagel, J.; Waldron, B. P.; Maina, T.; Nock, B. A.; Bergmann, R. K.; Ullrich, M.; Pietzsch, J.; Bachmann, M.; Baum, P. B.; Rösch, F.
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EJNMMI Research 9(2019), 48
DOI: 10.1186/s13550-019-0516-7
Cited 21 times in Scopus
T cells engrafted with a UniCAR 28/ζ outperform UniCAR BB/ζ-transduced T cells in the face of regulatory T cell-mediated immunosuppression
Kegler, A.; Koristka, S.; Bergmann, R.; Berndt, N.; Arndt, C.; Feldmann, A.; Hoffmann, A.; Bornhäuser, M.; Schmitz, M.; Bachmann, M.
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OncoImmunology 8(2019)9, e1621676
Online First (2019) DOI: 10.1080/2162402X.2019.1621676
Cited 16 times in Scopus
The UniCAR system: A modular CAR T cell approach to improve the safety of CAR T cells
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Immunology Letters 211(2019), 13-22
DOI: 10.1016/j.imlet.2019.05.003
Cited 73 times in Scopus
Midostaurin abrogates CD33-directed UniCAR and CD33-CD3 bispecific antibody therapy in acute myeloid leukemia
Fasslrinner, F.; Arndt, C.; Koristka, S.; Feldmann, A.; Altmann, H.; von Bonin, M.; Schmitz, M.; Bornhäuser, M.; Bachmann, M.
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British Journal of Haematology 186(2019)5, 735-740
DOI: 10.1111/bjh.15975
Cited 13 times in Scopus
An oligo-His-tag of a targeting module does not influence its biodistribution and the retargeting capabilities of UniCAR T cells
Jureczek, J.; Bergmann, R.; Berndt, N.; Koristka, S.; Kegler, A.; Puentes-Cala, E.; Soto, J. A.; Arndt, C.; Bachmann, M.; Feldmann, A.
-
Scientific Reports 9(2019)1, 10547
DOI: 10.1038/s41598-019-47044-4
Cited 15 times in Scopus
Fluorescent Mouse Pheochromocytoma Spheroids Expressing Hypoxia-Inducible Factor 2 alpha: Morphologic and Radiopharmacologic Characterization
Seifert, V.; Liers, J.; Kniess, T.; Richter, S.; Bechmann, N.; Feldmann, A.; Bachmann, M.; Eisenhofer, G.; Pietzsch, J.; Ullrich, M.
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Journal of Cellular Biotechnology 5(2019)2, 135-151
DOI: 10.3233/JCB-199005
ISSN: 2352-3689
Cited 8 times in Scopus
Synthesis and preliminary radiopharmacological characterisation of an 11C-labelled azadipeptide nitrile as potential PET tracer for imaging of cysteine cathepsins
Laube, M.; Frizler, M.; Wodtke, R.; Neuber, C.; Belter, B.; Kniess, T.; Bachmann, M.; Gütschow, M.; Pietzsch, J.; Löser, R.
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Journal of Labelled Compounds and Radiopharmaceuticals 62(2019)8, 448-459
DOI: 10.1002/jlcr.3729
Cited 10 times in Scopus
Tonic signaling and its effects on lymphopoiesis of CAR-armed hematopoietic stem and progenitor cells
Albert, S.; Koristka, S.; Gerbaulet, A.; Cartellieri, M.; Arndt, C.; Feldmann, A.; Berndt, N.; Loureiro, L.; von Bonin, M.; Ehninger, G.; Eugster, A.; Bonifacio, E.; Bornhäuser, M.; Bachmann, M.; Ehninger, A.
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Journal of Immunology 202(2019)6, 1735-1746
DOI: 10.4049/jimmunol.1801004
Cited 8 times in Scopus
Neoadjuvant radiochemotherapy significantly alters the phenotype of plasmacytoid dendritic cells and 6-sulfo LacNAc+ monocytes in rectal cancer
Wagner, F.; Hölig, U.; Wilczkowski, F.; Sommer, U.; Wehner, R.; Kießler, M.; Jarosch, A.; Plesca, I.; Flecke, K.; Arsova, M.; Tunger, A.; Bogner, A.; Reißfelder, C.; Weitz, J.; Schäkel, K.; Troost, E.; Krause, M.; Folprecht, G.; Bornhäuser, M.; Bachmann, M.; Aust, D.; Baretton, G.; Schmitz, M.
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Frontiers in Immunology 10(2019), 602
DOI: 10.3389/fimmu.2019.00602
Cited 10 times in Scopus
Anti-CAR engineered T cells for epitope-based elimination of autologous CAR T cells
Koristka, S.; Ziller-Walter, P.; Bergmann, R.; Arndt, C.; Feldmann, A.; Kegler, A.; Cartellieri, M.; Ehninger, A.; Ehninger, G.; Bornhäuser, M.; Bachmann, M.
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Cancer Immunology, Immunotherapy (2019), 1401-1415
Online First (2019) DOI: 10.1007/s00262-019-02376-y
Cited 28 times in Scopus
2018
Immune Monitoring of Cancer Patients Prior to and During CTLA-4 or PD-1/PD-L1 Inhibitor Treatment
Tunger, A.; Kießler, M.; Wehner, R.; Temme, A.; Meier, F.; Bachmann, M.; Schmitz, M.
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Biomedicines 6(2018)1, 26
DOI: 10.3390/biomedicines6010026
Cited 17 times in Scopus
Multimodal PET/MRI Imaging Results Enable Monitoring the Side Effects of Radiation Therapy.
Kovács, N.; Szigeti, K.; Hegedűs, N.; Horváth, I.; Veres, D. S.; Bachmann, M.; Bergmann, R.; Máthé, D.
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Contrast Media & Molecular Imaging (2018), 5906471
DOI: 10.1155/2018/5906471
Cited 5 times in Scopus
Improved Conjugation, 64-Cu Radiolabeling, in Vivo Stability, and Imaging Using Nonprotected Bifunctional Macrocyclic Ligands: Bis(Phosphinate) Cyclam (BPC) Chelators
David, T.; Hlinová, V.; Kubíček, V.; Bergmann, R.; Striese, F.; Berndt, N.; Szöllösi, D.; Hegedus, N.; Mathe, D.; Bachmann, M.; Pietzsch, H.-J.; Hermann, P.
Beteiligte Forschungsanlagen
- PET-Zentrum
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Journal of Medicinal Chemistry 61(2018), 8774-8796
Online First (2018) DOI: 10.1021/acs.jmedchem.8b00932
Cited 20 times in Scopus
Development of a novel target module redirecting UniCAR T cells to Sialyl Tn-expressing tumor cells
Loureiro, L.; Feldmann, A.; Bergmann, R.; Koristka, S.; Berndt, N.; Arndt, C.; Pietzsch, J.; Novo, C.; Videira, P.; Bachmann, M.
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Blood Cancer Journal 8(2018), 81
DOI: 10.1038/s41408-018-0113-4
Cited 40 times in Scopus
Strain-specific metastatic phenotypes in pheochromocytoma allograft mice
Ullrich, M.; Liers, J.; Peitzsch, M.; Feldmann, A.; Bergmann, R.; Sommer, U.; Richter, S.; Bornstein, S. R.; Bachmann, M.; Eisenhofer, G.; Ziegler, C. G.; Pietzsch, J.
Beteiligte Forschungsanlagen
- PET-Zentrum
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Endocrine-Related Cancer 25(2018)12, 993-1004
DOI: 10.1530/ERC-18-0136
Cited 7 times in Scopus
From mono- to bivalent: improving theranostic properties of target modules for redirection of UniCAR T cells against EGFR-expressing tumor cells in vitro and in vivo
Albert, S.; Arndt, C.; Koristka, S.; Berndt, N.; Bergmann, R.; Feldmann, A.; Schmitz, M.; Pietzsch, J.; Steinbach, J.; Bachmann, M.
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Oncotarget 9(2018)39, 25597-25616
DOI: 10.18632/oncotarget.25390
Cited 55 times in Scopus
Clinical translation and regulatory aspects of CAR/TCR-based adoptive cell therapies-the German Cancer Consortium approach.
Krackhardt, A. M.; Anliker, B.; Hildebrandt, M.; Bachmann, M.; Eichmüller, S. B.; Nettelbeck, D. M.; Renner, M.; Uharek, L.; Willimsky, G.; Schmitt, M.; Wels, W. S.; Schüssler-Lenz, M.
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Cancer Immunology, Immunotherapy 67(2018)4, 513-523
Online First (2018) DOI: 10.1007/s00262-018-2119-y
Cited 13 times in Scopus
Engrafting human regulatory T cells with a flexible modular chimeric antigen receptor technology
Koristka, S.; Kegler, A.; Bergmann, R.; Arndt, C.; Feldmann, A.; Albert, S.; Cartellieri, M.; Ehninger, A.; Ehninger, G.; Middeke, J. M.; Bornhäuser, M.; Schmitz, M.; Pietzsch, J.; Akgün, K.; Ziemssen, T.; Steinbach, J.; Bachmann, M. P.
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Journal of Autoimmunity 90(2018), 116-131
DOI: 10.1016/j.jaut.2018.02.006
Cited 65 times in Scopus
2017
An orthotopic xenograft model for high-risk non-muscle invasive bladder cancer in mice: influence of mouse strain, tumor cell count, dwell time and bladder pretreatment
Huebner, D.; Rieger, C.; Bergmann, R.; Ullrich, M.; Meister, S.; Toma, M.; Wiedemuth, R.; Temme, A.; Novotny, V.; Wirth, M. P.; Bachmann, M.; Pietzsch, J.; Fuessel, S.
Beteiligte Forschungsanlagen
- PET-Zentrum
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BMC Cancer 17(2017)1, 790
DOI: 10.1186/s12885-017-3778-3
Cited 17 times in Scopus
Exploratory investigation of PSCA-protein expression in primary breast cancer patients reveals a link to HER2/neu overexpression.
Link, T.; Kuithan, F.; Ehninger, A.; Kuhlmann, J. D.; Kramer, M.; Werner, A.; Gatzweiler, A.; Richter, B.; Ehninger, G.; Baretton, G.; Bachmann, M.; Wimberger, P.; Friedrich, K.
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Oncotarget 8(2017)33, 54592-54603
Online First (2017) DOI: 10.18632/oncotarget.17523
Cited 9 times in Scopus
Mass spectrometry-based identification of a naturally presented receptor tyrosine kinase-like orphan receptor 1-derived epitope recognized by CD8+ cytotoxic T cells
Heidenreich, F.; Rücker-Braun, E.; Walz, J. S.; Eugster, A.; Kühn, D.; Dietz, S.; Nelde, A.; Tunger, A.; Wehner, R.; Link, C. S.; Middeke, J. M.; Stölzel, F.; Tonn, T.; Stevanovic, S.; Rammensee, H. G.; Bonifacio, E.; Bachmann, M.; Zeis, M.; Ehninger, G.; Bornhäuser, M.; Schetelig, J.; Schmitz, M.
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Haematologica -The Hematology Journal 102(2017), e460-e464
DOI: 10.3324/haematol.2017.167312
Cited 7 times in Scopus
Novel Radiolabeled Bisphosphonates for PET Diagnosis and Endoradiotherapy of Bone Metastases
Pfannkuchen, N.; Meckel, M.; Bergmann, R.; Bachmann, M.; Bal, C.; Sathekge, M.; Mohnike, W.; Baum, R. P.; Rösch, F.
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Pharmaceuticals 10(2017), 45
Online First (2017) DOI: 10.3390/ph10020045
Cited 45 times in Scopus
Biological characterization of novel nitroimidazole-peptide conjugates in vitro and in vivo.
Bergmann, R.; Splith, K.; Pietzsch, J.; Bachmann, M.; Neundorf, I.
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Journal of Peptide Science 23(2017), 597-609
Online First (2017) DOI: 10.1002/psc.2995
Cited 7 times in Scopus
Characterization of a switchable chimeric antigen receptor platform in a pre-clinical solid tumor model
Bejestani, E. P.; Cartellieri, M.; Bergmann, R.; Ehninger, A.; Loff, S.; Kramer, M.; Spehr, J.; Dietrich, A.; Feldmann, A.; Albert, S.; Wermke, M.; Baumann, M.; Krause, M.; Bornhäuser, M.; Ehninger, G.; Bachmann, M.; von Bonin, M.
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OncoImmunology 6(2017)10, 1342909
Online First (2017) DOI: 10.1080/2162402X.2017.1342909
Cited 22 times in Scopus
Retargeting of UniCAR T cells with an in vivo synthesized target module directed against CD19 positive tumor cells
Bachmann, D.; Aliperta, R.; Bergmann, R.; Feldmann, A.; Koristka, S.; Arndt, C.; Loff, S.; Welzel, P. B.; Albert, S.; Kegler, A.; Ehninger, A.; Cartellieri, M.; Ehninger, G.; Bornhäuser, M.; von Bonin, M.; Werner, C.; Pietzsch, J.; Steinbach, J.; Bachmann, M.
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Oncotarget 9(2017), 7487-7500
DOI: 10.18632/oncotarget.23556
Cited 38 times in Scopus
Development of novel target modules for retargeting of UniCAR T cells to GD2 positive tumor cells
Mitwasi, N.; Feldmann, A.; Bergmann, R.; Berndt, N.; Arndt, C.; Koristka, S.; Kegler, A.; Jureczek, J.; Hoffmann, A.; Ehninger, A.; Cartellieri, M.; Albert, S.; Rössig, C.; Ehninger, G.; Pietzsch, J.; Steinbach, J.; Bachmann, M.
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Oncotarget 8(2017), 108584-108603
DOI: 10.18632/oncotarget.21017
Cited 42 times in Scopus
A novel nanobody-based target module for retargeting of T lymphocytes to EGFR-expressing cancer cells via the modular UniCAR platform
Albert, S.; Arndt, C.; Feldmann, A.; Bergmann, R.; Bachmann, D.; Koristka, S.; Ludwig, F.; Ziller-Walter, P.; Kegler, A.; Gärtner, S.; Schmitz, M.; Ehninger, A.; Cartellieri, M.; Ehninger, G.; Pietzsch, H.-J.; Pietzsch, J.; Steinbach, J.; Bachmann, M.
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OncoImmunology 6(2017)4, e1287246
Online First (2017) DOI: 10.1080/2162402X.2017.1287246
ISSN: 2162-402X
Cited 87 times in Scopus
Distribution and kinetics of the Kv1.3-blocking peptide HsTX1[R14A] in experimental rats
Bergmann, R.; Kubeil, M.; Zarschler, K.; Chhabra, S.; Tajhya, R. B.; Beeton, C.; Pennington, M. W.; Bachmann, M.; Norton, R. S.; Stephan, H.
Beteiligte Forschungsanlagen
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Scientific Reports 7(2017), 3756
DOI: 10.1038/s41598-017-03998-x
Cited 17 times in Scopus
Retargeting of T lymphocytes to PSCA- or PSMA positive prostate cancer cells using the novel modular chimeric antigen receptor platform technology “UniCAR”
Feldmann, A.; Arndt, C.; Bergmann, R.; Loff, S.; Cartellieri, M.; Bachmann, D.; Aliperta, R.; Hetzenecker, M.; Ludwig, F.; Albert, S.; Ziller-Walter, P.; Kegler, A.; Koristka, S.; Gärtner, S.; Schmitz, M.; Ehninger, A.; Ehninger, G.; Pietzsch, J.; Steinbach, J.; Bachmann, M.
Beteiligte Forschungsanlagen
- PET-Zentrum
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Oncotarget 8(2017)19, 31368-31385
DOI: 10.18632/oncotarget.15572
Cited 92 times in Scopus
Cryogel-Supported Stem Cell Factory for Customized Sustained Release of Bispecific Antibodies for Cancer Immunotherapy
Aliperta, R.; Welzel, P. B.; Bergmann, R.; Freudenberg, R.; Berndt, N.; Feldmann, A.; Arndt, C.; Koristka, S.; Stanzione, M.; Cartellieri, M.; Ehninger, A.; Ehninger, G.; Werner, C.; Pietzsch, J.; Steinbach, J.; Bornhäuser, M.; Bachmann, M.
Beteiligte Forschungsanlagen
- PET-Zentrum
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Scientific Reports 7(2017), 42855
Online First (2017) DOI: 10.1038/srep42855
Cited 51 times in Scopus
2016
Generation of high-avidity, WT1-reactive CD8+ cytotoxic T cell clones with anti-leukemic activity by streptamer technology
Tunger, A.; Wehner, R.; von Bonin, M.; Kühn, D.; Heidenreich, F.; Matko, S.; Nauerth, M.; Rücker-Braun, E.; Dietz, S.; Link, C. S.; Eugster, A.; Odendahl, M.; Busch, D. H.; Tonn, T.; Bonifacio, E.; Germeroth, L.; Schetelig, J.; Bachmann, M. P.; Bornhäuser, M.; Schmitz, M.
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Leukemia & Lymphoma 58(2016)5, 1246-1249
Online First (2016) DOI: 10.1080/10428194.2016.1233538
Cited 8 times in Scopus
Switching CAR T cells on and off: A novel modular platform for retargeting of T cells to AML blasts
Cartellieri, M.; Feldmann, A.; Koristka, S.; Arndt, C.; Loff, S.; Ehninger, A.; von Bonin, M.; Bejestani, E. P.; Ehninger, G.; Bachmann, M. P.
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Blood Cancer Journal 6(2016), e458
DOI: 10.1038/bcj.2016.61
Cited 176 times in Scopus
Multimodal Somatostatin Receptor Theranostics Using [64Cu]Cu-/[177Lu]Lu-DOTA-(Tyr3)octreotate and AN-238 in a Mouse Pheochromocytoma Model.
Ullrich, M.; Bergmann, R.; Peitzsch, M.; Zenker, E.; Cartellieri, M.; Bachmann, M.; Ehrhart-Bornstein, M.; Block, N.; Schally, A.; Eisenhofer, G.; Bornstein, S.; Pietzsch, J.; Ziegler, C.
Beteiligte Forschungsanlagen
- PET-Zentrum
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Theranostics 6(2016)5, 650-665
Online First (2016) DOI: 10.7150/thno.14479
Cited 36 times in Scopus
2015
Improved Killing of AML Blasts By Dual-Targeting of CD123 and CD33 Via Unitarg a Novel Antibody-Based Modular T Cell Retargeting System
Arndt, C.; Feldmann, A.; Koristka, S.; Cartellieri, M.; von Bonin, M.; Ehninger, A.; Bornhäuser, M.; Ehninger, G.; Bachmann, M. P.
- BLOOD 126(2015), 2565
Bispecific antibody releasing-mesenchymal stromal cell machinery for retargeting T cells towards acute myeloid leukemia blasts
Aliperta, R.; Cartellieri, M.; Feldmann, A.; Arndt, C.; Koristka, S.; Michalk, I.; von Bonin, M.; Ehninger, A.; Bachmann, J.; Ehninger, G.; Bornhäuser, M.; Bachmann, M. P.
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Blood Cancer Journal 5(2015), e348
Online First (2015) DOI: 10.1038/bcj.2015.73
Cited 25 times in Scopus
DAP12-Based Activating Chimeric Antigen Receptor for NK Cell Tumor Immunotherapy
Toepfer, K.; Cartellieri, M.; Michen, S.; Wiedemuth, R.; Mueller, N.; Lindemann, D.; Bachmann, M.; Fuessel, M.; Schackert, G.; Temme, A.
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Journal of Immunology 194(2015), 3201-3212
DOI: 10.4049/jimmunol.1400330
ISSN: 0022-1767
Cited 176 times in Scopus
Tregs activated by bispecific antibodies: Killers or suppressors?
Koristka, S.; Cartellieri, M.; Arndt, C.; Feldmann, A.; Seliger, B.; Ehninger, G.; Bachmann, M. P.
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OncoImmunology 4(2015)3, e994441
Online First (2015) DOI: 10.4161/2162402X.2014.994441
Cited 9 times in Scopus
2014
Dual Role of B7 Costimulation in Obesity-Related Nonalcoholic Steatohepatitis and Metabolic Dysregulation
Chatzigeorgiou, A.; Chung, K.-J.; Garcia-Martin, R.; Alexaki, V.-I.; Klotzsche-Von Ameln, A.; Phieler, J.; Sprott, D.; Kanczkowski, W.; Tzanavari, T.; Bdeir, M.; Bergmann, S.; Cartellieri, M.; Bachmann, M.; Nikolakopoulou, P.; Androutsellis-Theotokis, A.; Siegert, G.; Bornstein, S. R.; Muders, M. H.; Boon, L.; Karalis, K. P.; Lutgens, E.; Chavakis, T.
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Hepatology 60(2014), 1196-1210
DOI: 10.1002/hep.27233
ISSN: 0270-9139
Cited 56 times in Scopus
Redirection of CD4+ and CD8+ T lymphocytes via a novel antibody-based modular targeting system triggers efficient killing of PSCA+ prostate tumor cells
Arndt, C.; Feldmann, A.; Töpfer, K.; Koristka, S.; Cartellieri, M.; Temme, A.; Ehninger, A.; Ehninger, G.; Bachmann, M.
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The Prostate 74(2014), 1347-1358
DOI: 10.1002/pros.22851
Cited 23 times in Scopus
Proinflammatory human 6-sulfo LacNAc-positive dendritic cells accumulate in intestinal acute graft-versus-host disease
Sommer, U.; Larsson, B.; Tuve, S.; Wehner, R.; Zimmermann, N.; Kramer, M.; Kloß, A.; Günther, C.; Babatz, J.; Schmelz, R.; Brückner, S.; Schetelig, J.; Bornhäuser, M.; Schäkel, K.; Bachmann, M. P.; Aust, D.; Baretton, G.; Schmitz, M.
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Haematologica -The Hematology Journal 99(2014), e86-e89
DOI: 10.3324/haematol.2013.101071
ISSN: 1592-8721
Cited 8 times in Scopus
Simultaneous Targeting of Prostate Stem Cell Antigen and Prostate-Specific Membrane Antigen Improves the Killing of Prostate Cancer Cells Using a Novel Modular T Cell-Retargeting System
Arndt, C.; Feldmann, A.; Koristka, S.; Cartellieri, M.; Dimmel, M.; Ehninger, A.; Ehninger, G.; Bachmann, M.
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The Prostate 74(2014), 1335-1346
DOI: 10.1002/pros.22850
Cited 37 times in Scopus
A novel ex vivo Isolation and Expansion Procedure for Chimeric Antigen Receptor Engrafted Human T Cells
Cartellieri, M.; Koristka, S.; Arndt, C.; Feldmann, A.; Stamova, S.; von Bonin, M.; Töpfer, K.; Krüger, T.; Geib, M.; Michalk, I.; Temme, A.; Bornhäuser, M.; Lindemann, D.; Ehninger, G.; Bachmann, M. P.
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PLOS ONE 9(2014)4, e93745
DOI: 10.1371/journal.pone.0093745
Cited 37 times in Scopus
Characterization of a novel single-chain bispecific antibody for retargeting of T cells to tumor cells via the TCR co-receptor CD8
Michalk, I.; Feldmann, A.; Koristka, S.; Arndt, C.; Cartellieri, M.; Ehninger, A.; Ehninger, G.; Bachmann, M. P.
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PLOS ONE 9(2014)4, e95517
DOI: 10.1371/journal.pone.0095517
Cited 16 times in Scopus
Letter to the editor: Cytotoxic response of human regulatory 1 T cells upon T cell receptor-mediated activation – a 2 matter of purity
Koristka, S.; Cartellieri, M.; Arndt, C.; Feldmann, A.; Töpfer, K.; Michalk, I.; Temme, A.; Ehninger, G.; Bachmann, M.
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Blood Cancer Journal 4(2014), e199
Online First (2014) DOI: 10.1038/bcj.2014.20
Cited 10 times in Scopus
TCR/CD3 activation and co-stimulation combined in one T cell retargeting system improve anti-tumor immunity
Cartellieri, M.; Arndt, C.; Feldmann, A.; von Bonin, M.; Ewen, E.-M.; Koristka, S.; Michalk, I.; Stamova, S.; Berndt, N.; Gocht, A.; Bornhäuser, M.; Ehninger, G.; Schmitz, M.; Bachmann, M.
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OncoImmunology 2(2014)12, e26770
Online First (2014) DOI: 10.4161/onci.26770
Cited 9 times in Scopus
Costimulation improves the killing capability of T cells redirected to tumor cells expressing low levels of CD33: Description of a novel modular targeting system
Arndt, C.; Feldmann, A.; von Bonin, M.; Cartellieri, M.; Ewen, E.-M.; Koristka, S.; Michalk, I.; Stamova, S.; Berndt, N.; Gocht, A.; Bornhäuser, M.; Ehninger, G.; Schmitz, M.; Bachmann, M.
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Leukemia 28(2014), 59-69
DOI: 10.1038/leu.2013.243
ISSN: 0887-6924
Cited 56 times in Scopus