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33828 Publications

Intrinsic plasticity of silicon nanowire neurotransistors: plots of the figures 1-2

Baraban, L.

Data and Figures supporting the publication


Related publications
Intrinsic plasticity of silicon nanowire neurotransistors … (Id 31265) has used this publication of HZDR-primary research data
  • Reseach data in the HZDR data repository RODARE
    Publication date: 2020-07-01
    DOI: 10.14278/rodare.388
    License: CC-BY-4.0

Downloads:

Permalink: https://www.hzdr.de/publications/Publ-31280
Publ.-Id: 31280


Heisenberg limit for detecting vacuum birefringence

Ahmadiniaz, N.; Cowan, T.; Sauerbrey, R.; Schramm, U.; Schlenvoigt, H.-P.; Schützhold, R.

Quantum electrodynamics predicts the vacuum to behave as a nonlinear medium, including effects such as birefringence. However, for experimentally available field strengths, this vacuum polarizability is extremely small and thus very hard to measure. In analogy to the Heisenberg limit in quantum metrology, we study the minimum requirements for such a detection in a given strong field (the pump field). Using a laser pulse as the probe field, we find that its energy must exceed a certain threshold depending on the interaction time. However, a detection at that threshold, i.e., the Heisenberg limit, requires highly nonlinear measurement schemes--while for ordinary linear-optics schemes, the required energy (Poisson or shot noise limit) is much larger. Finally, we discuss several currently considered experimental scenarios from this point of view.

Keywords: Quantum Electrodynamics; Vacuum birefringence; Heisenberg limit

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Permalink: https://www.hzdr.de/publications/Publ-31277
Publ.-Id: 31277


Status of the STM-FPGA-DAQ HLS-Cores for LaBr Peak Detection and Zero Suppression

Knodel, O.

Brief overview and status of the STM-FPGA-DAQ HLS-Cores for LaBr peak detection, moving window deconvolution and zero suppression

Keywords: Data Management; DAQ; FPGA; Mu2e

  • Invited lecture (Conferences) (Online presentation)
    Mu2e Collaboration Meeting, STM Workshop, 16.06.2020, Online, Online

Permalink: https://www.hzdr.de/publications/Publ-31275
Publ.-Id: 31275


Interprofessionelle Kooperation: Bedarf und Komplexizität bei prospektiv-nuklearmedizinischen Studien am Beispiel des DKTK-Multicenter-Trials mit [68Ga]Ga-PSMA-11

Zippel, C.; Neels, O.; Biedenstein, S.; Giesel, F. L.; Kopka, K.

Ziel/Aim: Um neue PET-Tracer in die Patientenversorgung überführen zu können, werden in der nuklearmedizinischen Forschung zunehmend prospektiv-klinische Studien mit den vielversprechendsten Radioliganden initiiert. Damit diese Studien möglichst effizient und effektiv durchgeführt werden können, bedarf es der möglichst engen Kooperation und Kommunikation von Expert*innen aus verschiedenen Berufsgruppen.

Methodik/Methods: Wir beleuchten am Beispiel der Multicenter-Studie „Ga-68-PSMA-11 in Hochrisiko-Prostatakrebs“ der Phasen-I/-II, welche wesentlichen Professionen aus forschender Klinik, Wirkstoffherstellung und Verwaltung bei der Planung, Vorbereitung und Durchführung prospektiv-nuklearmedizinischer Studien involviert sein können und welche Aufgaben diese zur Studienverwirklichung wahrnehmen. Darauf aufbauend leiten wir organisatorische Maßnahmen ab, durch die die interprofessionelle Kooperation bei prospektiven Bildgebungsstudien (auch über mehrere Prüfzentren) gefördert werden kann.

Ergebnisse/Results: In die Beispielstudie sind im engeren fachlichen Kreis Mediziner aus Nuklearmedizin/Urologie/Pathologie, MTA-Rs, Studienassistenten, Radiochemiker/-pharmazeuten, BTA/CTA, MTA und Gesundheits-/Krankenpfleger involviert. Im weiteren fachlichen Kreis sind ferner Strahlenschutzbeauftragte, Qualitätsmanager, klinische Monitore, Juristen, Datenschutzbeauftragte, Projektmanager und Studienkoordinatoren eingebunden, und dies jeweils an bis zu elf Prüfzentren in Deutschland, Österreich und der Schweiz.

Schlussfolgerungen/Conclusions: Interprofessionelle Kooperation ist für die Durchführung prospektiv-nuklearmedizinischer Studien essentiell. Hierzu bedarf es u.a. der grundlegenden Bereitschaft, sich in andere (Tätigkeits-)Rollen hineinzuversetzen und über Professionsgrenzen hinaus kooperieren zu wollen, ausreichend Zeit zum gegenseitigen Austausch, Fähigkeit/Fertigkeiten zum berufsübergreifenden Projektmanagement und eine integrale Betrachtung benötigter Expertisen mit Stärkung professionsübergreifender Kommunikation insbesondere über die Leitungsebene.

  • Lecture (Conference) (Online presentation)
    58. DGN-Jahrestagung 2020, 06.-09.07.2020, Leipzig, Deutschland
    DOI: 10.1055/s-0040-1708427

Permalink: https://www.hzdr.de/publications/Publ-31274
Publ.-Id: 31274


GMP Requirements for a Clinical Trial with 68Ga-PSMA-11 - Experience from a Multi-Centre Trial

Neels, O.

Without abstract

  • Invited lecture (Conferences)
    Annual Congress of the European Association of Nuclear Medicine, October 15 – 19, 2016, Barcelona, Spain, 15.-19.10.2016, Barcelona, Spanien
    DOI: 10.1007/s00259-016-3484-4

Permalink: https://www.hzdr.de/publications/Publ-31273
Publ.-Id: 31273


Molecular Imaging of Prostate Cancer: A direct comparison of the preclinical characteristics of [18F]DCFPyL and [18F]PSMA-1007 and the impact of glutamic acids on [18F]PSMA-1007

Roscher, M.; Remde, Y.; Schäfer, M.; Bauder-Wüst, U.; Giesel, F.; Neels, O.; Cardinale, J.; Kopka, K.

Aim: For the imaging of PSMA-positive prostate cancer, several fluorine-18 (18F)-labelled compounds have been developed and translated into the clinics. Next to a clinical study comparing the tracer-specific characteristics of [18F]DCFPyL and [18F]PSMA-1007 intra-individually(1), a direct comparison of their preclinical characteristics has only recently been published(2). In this work, the importance of glutamic acids in the structure of [18F]PSMA-1007 is further elucidated using derivatives with none to three glutamic acids (Glu), respectively. Furthermore, [18F]DCFPyL and [18F]PSMA-1007 are evaluated regarding their preclinical characteristics using the in vitro and in vivo methods established at DKFZ Heidelberg, Germany. Materials and Methods: The precursors for radiofluorination containing different amino acid linkers (0-3 Glu) were synthesized by means of solid phase chemistry. The radiolabeling of [18F]PSMA-1007, its derivatives, and [18F]DCFPyL were performed prior to each experiment as described(3,4). The binding affinities of non-radioactive reference compounds were determined by competitive binding assays against [68Ga]Ga-PSMA-10 in LNCaP cells. The internalization of the respective radioligands in LNCaP cells was compared. Biodistribution and pharmacokinetics were evaluated in vivo in LNCaP-tumor bearing BALB/c Nude mice using μPET. Results: The Glu variation in the linker structure resulted in similar binding affinities (Ki 3-14 nM) whereby the insertion of three Glu showed the highest Ki values. Internalization assays revealed that the insertion of Glu influences the internalization rate, whereby the insertion of two Glu ([18F]PSMA-1007) leads to the highest internalization rate (54.04±13.7%) in a total range between 27.3±3% to 54±13.7%. In comparison to [18F]PSMA-1007, a higher proportion of [18F]DCFPyL remains cell surface bound; only 27.83 ± 4.31% of the radiotracer is internalized. [18F]DCFPyL also has a slightly lower binding affinity (18.02±9.63 nM). μPET imaging showed outstanding imaging properties, especially of [18F]DCFPyL and [18F]PSMA-1007. In mice, the liver uptake is reduced by introduction of Glu linkers. The data will be analysed more detailed soon. Conclusion: Comparative cell experiments revealed a high binding affinity for all tracers and the highest internalization rate for [18F]PSMA-1007. The insertion of Glu in the linker structure plays an important role in pharmacokinetics due to the decreased lipophilicity of the respective radiotracer. Especially [18F]DCFPyL and [18F]PSMA-1007 are of excellent imaging quality. Their apparent non-inferiority is currently under further assessment in clinical trials. References: (1) Giesel F et al (2017): JNM, doi: 10.2967/jnumed.117.204669. (2) Robu S et al (2018): EJNMMI Res., 8(1):30. (3) Cardinale J et al. (2017): JNM, 58(3):425-431. (4) Chen Y et al. (2011): Clin Cancer Res., 17(24):7645-53.

  • Lecture (Conference)
    Annual Congress of the European Association of Nuclear Medicine, October 13 – 17, 2018, Düsseldorf, Germany, 13.-17.10.2018, Düsseldorf, Deutschland
    DOI: 10.1007/s00259-018-4148-3

Permalink: https://www.hzdr.de/publications/Publ-31272
Publ.-Id: 31272


Initiation Of A Prospective Clinical Multicentre Trial With Local Production Of A Short-Lived PSMA-PET Radiopharmaceutical In The D-A-CH-Region: Chances And Experiences

Neels, O.; Zippel, C.; Giesel, F. L.; Kopka, K.

Aim/Introduction: The development of innovative radiotracers targeting PSMA for non-invasive imaging of prostate cancer and successive treatment results in an increasing number of multicentre clinical trials using the most promising PSMA ligand candidates. For prospective studies with short-lived radiopharmaceuticals like [68Ga]Ga-PSMA-11, a regulatory and country-specific structure has to be established before recruitment of patients is possible. This structure allows the decentralized manufacturing of the investigational medicinal product (IMP) according to Good Manufacturing (GMP) and subsequent implementation of the respective tracer compliant with Good Clinical Practice (GCP). Materials and Methods: For the multicenter clinical trial (phases-I/-II) ,,Ga-68-PSMA-11 in high-risk prostate cancer“ (NCT03362359) within DKTK a harmonized decentralized radiotracer production in multiple radiopharmacies has been set up for the very first time in the German speaking Radiopharmacy/Nuclear Medicine Community. In this prospective clinical study Nuclear Medicine physicians, radiopharmacists, urologists, pathologists and study related experts like lawyers and study nurses out of eleven study sites within the so-called D-A-CH region (Germany-Austria-Switzerland) have been involved. The basis for the accurately specified radioactive IMP manufacturing procedure was defined by EU-GMP requirements plus national standards (e.g. Medicinal Products Act and Radiation Protection Law). Results: For the recruiting study sites the required allowances, e.g. manufacturing authorization from local authorities as well as approval from ethics committees and national regulatory bodies such as BfS and BfArM in Germany, BASG in Austria as well as BAG and Swissmedic in Switzerland, have been obtained. The challenge of manufacturing a short-lived radiopharmaceutical at each of the participating geographically different sites with identical specification by adaption of production and quality control processes and parameters according to the IMP dossier (IMPD) during the starting phase of the clinical trial under a centralized quality assurance management has been achieved. Conclusion: The initiation and establishment of a multicentre clinical trial including the manufacturing of a short-lived radiopharmaceutical IMP across local study sites is very complex, but manageable. In view of the high European and national regulatory and legal burdens and the number of involved partners it is feasible in a defined time frame. Based on the achieved structures, the decentralized manufacture of novel short-lived radiopharmaceuticals can be established in the D-A-CH region and even on a European level for further investigator initiated multicentre clinical trials. We estimate our experiences important for the development of the field Nuclear Medicine at the national and international level taking into account the new EU regulation No 536/2014. References: None.

  • Poster
    Annual Congress of the European Association of Nuclear Medicine, October 12 – 16, 2019, Barcelona, Spain, 12.-16.10.2019, Barcelona, Spanien
    DOI: 10.1007/s00259-019-04486-2

Permalink: https://www.hzdr.de/publications/Publ-31271
Publ.-Id: 31271


Too many regulations

Neels, O.

Without abstract

  • Invited lecture (Conferences)
    Annual Congress of the European Association of Nuclear Medicine, October 12 – 16, 2019 Barcelona, Spain, 12.-16.10.2019, Barcelona, Spanien
    DOI: 10.1007/s00259-019-04486-2

Permalink: https://www.hzdr.de/publications/Publ-31270
Publ.-Id: 31270


Supplmentary Video sets for the publication

Baraban, L.

6 supplementary videos


Related publications
Inverse Solidification Induced by Active Janus Particles (Id 31267) has used this publication of HZDR-primary research data
  • Reseach data in the HZDR data repository RODARE
    Publication date: 2020-06-29
    DOI: 10.14278/rodare.384
    License: CC-BY-4.0

Downloads:

Permalink: https://www.hzdr.de/publications/Publ-31268
Publ.-Id: 31268


P1819 - Verfahren zur Herstellung eines keramischen Materials mit lokal einstellbarem Permeabilitätsgradienten, dessen Anwendung in einem Beschichtungsverfahren sowie dessen Verwendung

Bürger, D.; Krüger, S.; Skorupa, I.; Schmidt, H.; Du, N.

Die Erfindung betrifft ein Verfahren zur Herstellung eines keramischen Materials mit lokal einstellbarem Permeabilitätsgradienten, dessen Anwendung in einem Beschichtungsverfahren- Materialbearbeitungsverfahren sowie dessen Verwendung. Die Aufgabe ein Material zur Verfügung zu stellen, welches zum Leiten und Isolieren von Magnetfeldern geeignet ist sowie in magnetischen Kopplungselementen verwendet werden kann, wird durch ein Verfahren zur Herstellung eines keramischen Materials mit lokal einstellbarem Permeabilitätsgradienten gelöst, wobei das Verfahren folgende Schritte umfasst: - Erzeugen eines keramischen Materials mittels Erhitzen einer Ausgangsmaterialkomposition bis zu einer Temperatur unterhalb der Schmelztemperatur der Ausgangsmaterialkomposition, - Abkühlen des erzeugten keramischen Materials auf Raumtemperatur nach einer definierten Abkühlrate zur Einstellung einer Vortex-Dichte in dem erzeugten keramischen Material, und - nachfolgende lokale Temperaturbehandlung zum Erhitzen des keramischen Materials über dessen ferroelektrische Ordnungstemperatur und zum Einstellen des lokalen Permeabilitätsgradienten.

  • Patent
    DE102018125270 - Offenlegung 16.04.2020; Nachanmeldungen: WO

Permalink: https://www.hzdr.de/publications/Publ-31256
Publ.-Id: 31256


Small Crown-Ether Complexes as Molecular Models for Dihydrogen Adsorption in Undercoordinated Extraframework Cations in Zeolites

Wulf, T.; Heine, T.

1:1 metal complexes of small crown ethers are structurally similar to extraframework sites in metal-exchanged zeolites. Using ab initio calculations, we show that adsorbed molecular hydrogen follows the same trends in adsorption energies and vibrational frequencies at both types of metal sites. Unlike zeolites, crown ethers can be characterized in the gas phase, which opens new possibilities for understanding the bonding of dihydrogen at undercoordinated metal sites to help guide the rational design of porous materials for hydrogen isotope separation. Because more strongly binding adsorbates affect the geometry of the hosts, the similarity of crown ethers and zeolites with regard to the vibrational spectra of the adsorbed molecule seems to be limited to H₂.

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Permalink: https://www.hzdr.de/publications/Publ-31241
Publ.-Id: 31241


Convection Caused Symmetry Breaking of Azimuthal Magnetorotational Instability in a Liquid Metal Taylor Couette Flow

Seilmayer, M.; Ogbonna, J. E.; Stefani, F.

This are the experimental and numerical results for the publication "Convection Caused Symmetry Breaking of Azimuthal Magnetorotational Instability in a Liquid Metal Taylor Couette Flow ". It contains pictures, experimental results, tex files, COMSOL simulation file and PDF.

Keywords: MRI, magnetohydrodynamic, thermal convection, Taylor Couette


Related publications
Convection Caused Symmetry Breaking of Azimuthal … (Id 28445) has used this publication of HZDR-primary research data
  • Reseach data in the HZDR data repository RODARE
    Publication date: 2020-06-25
    DOI: 10.14278/rodare.380
    License: CC-BY-4.0

Downloads:

Permalink: https://www.hzdr.de/publications/Publ-31238
Publ.-Id: 31238


ExploreASL/ExploreASL: First stable release

Mutsaerts, H.; Petr, J.; Stritt, M.; Vandemaele, P.; Groot, P.

ExploreASL v1.0.0

  • Software in external data repository
    Publication year 2020
    Programming language: Matlab
    System requirements: Windows/Linux/OS X
    License: Other (Open)
    Hosted on https://github.com/ExploreASL/ExploreASL/tree/v1.0.0:
    DOI: 10.5281/zenodo.3905263

Permalink: https://www.hzdr.de/publications/Publ-31229
Publ.-Id: 31229


P1818 - Verfahren zur gezielten Auswahl eines Sensors zur sensorbasierten Sortierung eines Materialgemisches durch Simulation der sensorbasierten Sortierung des Materialgemisches

Kern, M.; Tusa, L.; Gutzmer, J.; van den Boogaart, K. G.

Es wird Verfahren zur Auswahl eines Sensors (1) aus einer Mehrzahl von Sensoren zur sensorbasierten Sortierung eines Materialgemischs (10) anhand einer Materialeigenschaft zur Konzentration eines Wertstoffes vorgeschlagen, wobei in einem ersten Schritt aus dem Materialgemisch (10) repräsentative Einzelproben gewonnen werden (20), in einem zweiten Schritt Materialeigenschaften der Einzelproben gemessen werden (30), in einem dritten Schritt auf Grundlage der gemessenen Materialeigenschaften eine Mehrzahl von simulierten Sortierungen anhand jeweils unterschiedlicher Materialeigenschaften simuliert wird (40), in einem vierten Schritt eine simulierte Sortierung mit einer hohen Wertstoffkonzentration aus der Mehrzahl von simulierten Sortierungen ausgewählt wird, in einem fünften Schritt ein Sensor (1) zur Messung der Materialeigenschaft ausgewählt wird (50), welcher geeignet ist, mindestens eine der Materialeigenschaften, welche für die ausgewählte simulierte Sortierung genutzt wurde, zu messen.

  • Patent
    DE102018217548 - Offenlegung 16.04.2020; Nachanmeldungen: WO

Permalink: https://www.hzdr.de/publications/Publ-31227
Publ.-Id: 31227


P1816 - Reaktor und Verfahren zur kontinuierlichen Gewinnung amphiphiler Siderophore aus einer Mikroorganismenkultur

Schrader, S.; Kutschke, S.; Pollmann, K.; Rudolph, M.

Die Erfindung betrifft einen Reaktor, ein Verfahren und die Verwendung dieses Reaktors in dem Verfahren zur Gewinnung amphiphiler Siderophore aus einer Mikroorganismenkultur. Der Reaktor umfasst die Bauteile: (a) Vorrichtung (40) zum Rühren und/oder Begasen, und (b) Ablauf (70) für Schaum, enthaltend die amphiphilen Siderophore, in der Seitenwand des Reaktors, (c) Deckel (90) wobei die Unterkante des Ablaufs (70) für Schaum als Überlauf in einer Höhe liegt, die im Bereich von 40-75% der Gesamthöhe des Reaktors (10), von unten gemessen, liegt, und wobei der Ablauf (70) für Schaum horizontal nach außen oder schräg nach unten außen verläuft oder als Überlauf ausgestaltet ist.

  • Patent
    DE102018122029 - Offenlegung 12.03.2020; Nachanmeldungen: WO

Permalink: https://www.hzdr.de/publications/Publ-31226
Publ.-Id: 31226


P1814 - Kühlvorrichtung sowie Kühlverfahren basierend auf magnetoelektrischer Kopplung

Hornung, J.; Gottschall, T.

Verschiedene Ausführungsformen betreffen ein Verfahren (700) zum Betreiben einer Kühlvorrichtung (300), das Verfahren (700) aufweisend: ein erstes Verändern eines elektrischen Feldes (304) in einem Feldbereich (306), wobei in dem Feldbereich (306) mindestens ein Magnetsystem mit magnetoelektrischer Kopplung angeordnet ist, und dadurch Erwärmen des mindestens einen Magnetsystems; und, anschließend, ein zweites Verändern des elektrischen Feldes (304) in dem Feldbereich (306) und dadurch Abkühlen des mindestens einen Magnetsystems.

  • Patent
    DE102018118813 - Erteilung 21.11.2019

Permalink: https://www.hzdr.de/publications/Publ-31225
Publ.-Id: 31225


P1813 - Schichtabfolge zur Erzeugung von Elektrolumineszenz und deren Verwendung

Bogusz, A.; Rayapati, V. R.; Skorupa, I.; Schmidt, H.; Bürger, D.; Krüger, S.; Rebohle, L.

Die Erfindung betrifft eine Schichtabfolge zur Erzeugung von Elektrolumineszenz und deren Verwendung, beispielsweise in einem Pixelarray oder in textilen Materialien. Die Aufgabe eine Schichtstruktur anzugeben, die einfach realisierbar bzw. herstellbar sowie einfach aufgebaut ist, mit der Elektrolumineszenz einfach erzeugt werden kann und langzeitstabil einsetzbar ist, wird durch eine Schichtabfolge zur Erzeugung von Elektrolumineszenz
gelöst, die mindestens eine polykristalline Seltene-Erd-Manganat-Schicht sowie einen ersten Kontakt, der auf einer Seite der Seltene-Erd-Manganat-Schicht angeordnet ist sowie einen zweiten Kontakt, der auf der gegenüberliegenden Seite des ersten Kontaktes oder auf der gleichen Seite wie der
erste Kontakt angeordnet ist, aufweist, wobei in der Seltene-Erd-Manganat-Schicht zwischen dem ersten Kontakt und dem zweiten Kontakt ein Widerstand größer als 100 Ohm ausgebildet ist und wobei die Seltene-Erd-Manganat-Schicht geeignet ist, bei Anlegen einer elektrischen Gleichspannung, lokal im Bereich des sich zwischen den beiden elektrisch leitenden Kontakten ausbildenden elektrischen Feldes in der Seltene-Erd-Manganat-Schicht eine Elektrolumineszenz aufgrund von Stoßionisation auszubilden.

  • Patent
    DE102018117210 - Offenlegung 20.02.2020

Permalink: https://www.hzdr.de/publications/Publ-31224
Publ.-Id: 31224


P1812 - Fluidik-Detektionssystem

Illing, R.; Makarov, D.

Die Erfindung betrifft ein Fluidik-Detektionssystem zur magnetisch-elektrischen Messung einer fluiden Probe, wobei das System jeweils mindestens ein Probenmodul, einen Magnetfeldsensor und einen Magneten umfasst, welche voneinander beabstandet angeordnet sind. Dabei weist das Probenmodul mindestens einen Kanal auf, der zum Befördern einer fluiden Probe entlang einer Fließrichtung ausgebildet ist. Der Magnet erzeugt ein Magnetfeld in einem Mess- und Anregungsbereich des Kanals. Dabei entspricht der Detektionsbereich des Magnetfeldsensors dem Mess- und Anregungsbereich des Kanals. Beim Befördern der fluiden Probe im Mess- und Anregungsbereich des Kanals wird das Magnetfeld von der zu untersuchenden fluiden Probe modifiziert, wobei der Magnetfeldsensor das modifizierte Magnetfeld erfasst. Die Erfindung betrifft weiterhin ein Verfahren zum Betrieb des erfindungsgemäßen Fluidik-Detektionssystems zur magnetisch-elektrischen Messung einer fluiden Probe.

  • Patent
    DE102018116918 - Offenlegung 16.01.2020; Nachanmeldungen: WO

Permalink: https://www.hzdr.de/publications/Publ-31223
Publ.-Id: 31223


P1810 - 2-Phenoxypyridin-3-amin-Derivate und deren Verwendung

Moldovan, R.-P.; Wenzel, B.; Teodoro, R.; Dukic-Stefanovic, S.; Deuther-Conrad, W.; Brust, P.

Die Erfindung betrifft eine Verbindung der allgemeinen Formel I worin R¹ aus der Gruppe ausgewählt ist, die aus einer C₁-C₁₂-Alkylgruppe, einer C₃-C₁₂-Cycloalkylgruppe und einer Hetrocycloalkylgruppe mit 5 bis 12 Ringatomen, wobei die Ringatome Kohlenstoff und 1 bis 4 Heteroatome, ausgewählt aus N, O und S, sind, besteht; R² Wasserstoff oder Fluor ist, R³ eine Gruppe der Formel II oder eine Gruppe der Formel III ist: X¹ aus der Gruppe ausgewählt ist, die aus -(CR⁵R⁶)ₘ-, -(CR⁵R⁶)ₙC(O)-(CR⁵R⁶)ₚ- und -(CR⁵R⁶)q-X2-(CR⁵R⁶)ᵣ- besteht, wobei m, n, p, q und r unabhängig voneinander jeweils 0 oder eine Ganzzahl von 1 bis 6 sind; R⁴ aus der Gruppe ausgewählt ist, die aus einer Arylgruppe, einer Heteroarylgruppe mit 5 bis 12 Ringatomen, wobei die Ringatome Kohlenstoff und 1 bis 4 Heteroatome, ausgewählt aus N, O und S, sind, einer C₃-C₁₂-Cycloalkylgruppe und einer Heterocycloalkylgruppe mit 5 bis 12 Ringatomen, wobei die Ringatome Kohlenstoff und 1 bis 4 Heteroatome, ausgewählt aus N, O und S, sind, besteht; Ring A eine Arylgruppe oder eine Heteroarylgruppe mit 5 bis 12 Ringatomen, wobei die Ringatome Kohlenstoff und 1 bis 4 Heteroatome, ausgewählt aus N, O und S, sind, ist.

  • Patent
    DE102018113646 - Offenlegung 12.12.2019

Permalink: https://www.hzdr.de/publications/Publ-31222
Publ.-Id: 31222


P1809 - Verfahren zur Rekonfiguration einer Vortex-Dichte in einem Seltenen-Erd-Manganat, ein nichtflüchtiger Impedanzschalter und dessen Verwendung

Bogusz, A.; Krüger, S.; Skorupa, I.; Schmidt, H.; Du, N.

Die Erfindung beschreibt ein Verfahren zur Rekonfiguration einer Vortex-Dichte in einem Seltene-Erd-Manganat sowie einen nichtflüchtigen Impedanzschalter mit rekonfigurierbarer Impedanz. Die Aufgabe ein Verfahren anzugeben, mittels dem in speziellen Materialien deren Impedanz in Abhängigkeit von einer Vortex-Dichte ohne großen Aufwand beeinflusst und eingestellte werden kann, wird durch ein Verfahren zur Rekonfiguration einer Vortex-Dichte in einem Seltene-Erd-Manganat gelöst, wobei ein einmaliges Spannungs-Zeit-Profil zwischen einem ersten und einem zweiten, an das Seltene-Erd-Manganat angebrachten elektrisch leitenden Kontakt angelegt wird, so dass das Seltene-Erd-Manganat in einem Bereich eines sich zwischen den beiden elektrisch leitenden Kontakten ausbildenden elektrischen Feldes während eines Abkühlvorganges während und nach Anlegen des Spannungspulses oder der Spannungsrampe eine Ordnungstemperatur durchläuft und damit die Vortex-Dichte lokal im Bereich des sich zwischen den beiden elektrisch leitenden Kontakten ausbildenden elektrischen Feldes beeinflusst und eingestellt wird.

  • Patent
    DE102018112605 - Offenlegung 28.11.2019; Nachanmeldungen: WO

Permalink: https://www.hzdr.de/publications/Publ-31221
Publ.-Id: 31221


P1808 - Festbettreaktor

Schubert, M.

Die Erfindung betrifft einen Festbettreaktor (1) mit einem rohrförmigen Reaktionsbehälter (2), der einen Rohrmantel (7), der einen Innenraum (14) begrenzt, und eine Längsachse (B) aufweist, die gegen die Horizontale geneigt ist und um die der Reaktionsbehälter (2) drehbar ist. Dabei ist vorgesehen, dass in dem Innenraum (14) ein Verdrängungskörper (15) unter Ausbildung eines umlaufenden Spaltes (20) zwischen dem Verdrängungskörper (15) und dem Rohrmantel (7) angeordnet ist, wobei im Betriebszustand des Festbettreaktors (1) ein Festbett (13) aus einem Katalysatormaterial in dem Spalt (20) fixiert ist, das von zumindest einer Flüssigkeit (51) und zumindest einem Gas (52) durchströmt ist.

  • Patent
    DE102018110091 - Offenlegung 31.10.2019

Permalink: https://www.hzdr.de/publications/Publ-31220
Publ.-Id: 31220


P1807 - Multisensorisches therapeutisch-diagnostisches System zum Monitoring des orthopädischen Trainings und der sportlichen Leistung

Canon Bermudez, G. S.; Voitsekhivska, T.; Makarov, D.; Fuchs, H.; Tsvyakh, A.; Hospodarskyy, A.; Shevchuk, O.

Die Erfindung betrifft ein multisensorisches therapeutisch-diagnostisches System zum Monitoring des orthopädischen Trainings und der sportlichen Leistung mit voneinander beabstandeten elektrischen Komponenten, welche eine Datenverarbeitungseinrichtung, einen Energiespeicher, ein Sensorsystem zur Erfassung von Daten sowie eine Trageeinrichtung aufweisen, wobei die elektrischen Komponenten zumindest teilweise in oder an der Trageeinrichtung angeordnet sind. Weiterhin betrifft die Erfindung ein Verfahren zum Monitoring des orthopädischen Trainings und der sportlichen Leistung sowie ein Computerprogrammprodukt zur Durchführung des Verfahrens.

  • Patent
    DE102018109913 - Offenlegung 31.10.2019; Nachanmeldungen: WO

Permalink: https://www.hzdr.de/publications/Publ-31219
Publ.-Id: 31219


P1806 - Rückgewinnung von Metallen aus Industrieabwässern geringer Metall-Konzentration

Jain, R.; Pollmann, K.; Lehmann, F.

Die Erfindung stellt ein mehrstufiges Verfahren bereit, zur selektiven, umweltfreundlichen und kostengünstigen Rückgewinnung von Nichteisenmetallen aus Industrieabwässern. Das Verfahren basiert auf dem Prinzip der Komplexierung der Nichteisenmetalle, Abtrennung der Komplexe und anschließender Dekomplexierung der Nichteisenmetalle. Zur Anwendung kommen als Komplexbildner Siderophore, die innerhalb des Prozesses zurückgewonnen werden. Das Verfahren ist insbesondere auch bei geringen Nichteisenmetall-Konzentrationen anwendbar. Es ist effizient, umweltfreundlich und kostengünstig.

  • Patent
    DE102018107923 - Offenlegung 10.10.2019; Nachanmeldungen: WO, EP, JP, KR, US

Permalink: https://www.hzdr.de/publications/Publ-31218
Publ.-Id: 31218


P1805 - Transparenter Objektträger

Rebohle, L.; Wiesenhütter, K.; Skorupa, I.; Schmidt, H.

Die Erfindung betrifft einen transparenten Objektträger. Die Aufgabe der Erfindung einen Objektträger anzugeben, an dem die Reichweite sowie die Stärke der oberflächennahen, elektrostatischen Kräfte, während eines Herstellungsprozesses des Objektträgers zu beeinflussen und einzustellen sind, wird durch einen transparenten Objektträger gelöst, welcher eine aufnahmeseitige Oberfläche und eine von der Aufnahmeseite abgewandte, also rückseitige Oberfläche ausweist und mindestens drei Schichten umfasst: eine elektrisch isolierende erste Schicht, eine auf der ersten Schicht angeordnete siliziumhaltige zweite Schicht sowie eine auf der zweiten Schicht angeordnete elektrisch isolierende dritte Schicht, wobei sich jeweils eine Grenzfläche zwischen der ersten und zweiten Schicht sowie zwischen der zweiten und dritten Schicht ausbildet, wobei die Grenzfläche zwischen der ersten und zweiten Schicht eine erste Flächenladungsdichte aufweist und die Grenzfläche zwischen der zweiten und dritten Schicht eine zweite Flächenladungsdichte aufweist, wobei die erste und zweite Flächenladungsdichte gleiche oder unterschiedliche Vorzeichen aufweisen und der Objektträger oberflächennahe, elektrostatischen Kräfte auf beiden Oberflächenseiten aufweist, deren Reichweite sowie Stärke während des Herstellungsprozesses zu beeinflussen und einzustellen sind.

  • Patent
    DE102018107810 - Offenlegung 10.10.2019; Nachanmeldungen: WO

Permalink: https://www.hzdr.de/publications/Publ-31217
Publ.-Id: 31217


P1804 - Verfahren zur kontinuierlichen Bestimmung sämtlicher Komponenten eines Widerstandstensors von Dünnschichten

Kosub, T.

Die Erfindung betrifft ein Verfahren zur kontinuierlichen Bestimmung sämtlicher Komponenten eines Widerstandstensors von Dünnschichten, wie Dünnschichtwiderständen und Dünnschichtsensoren aller Art. Durch die Erfindung soll ein Verfahren zur kontinuierlichen Bestimmung sämtlicher Komponenten eines Widerstandstensors von Dünnschichten, wie Dünnschichtwiderständen und Dünnschichtsensoren aller Art, geschaffen werden, bei dem mit einer minimierten Anzahl von Kontakten eine kontinuierliche Bestimmung aller Komponenten des Widerstandstensors ohne Umschalten der Kontaktpunkte ermöglicht wird. Erreicht wird das dadurch, dass ein beliebig geformtes homogenes Teilstück (T) der Dünnschicht mit mindestens drei in Abständen zueinander angeordneten Kontaktpunkten (K₁ bis K₃) versehen wird, wobei an jedem der Kontaktpunkte (K₁ bis K₃) eine Eingangsspannung Uᵢ(t) angelegt wird, dass die die Kontaktpunkte (K₁ bis K₃) durchfließenden Ströme Iᵢ(t) erfasst werden und dass aus den Spannungs- und Stromwerten der vollständige Widerstandstensor p des Teilstücks (T) der Dünnschicht bestimmt wird.

  • Patent
    DE102018106466 - Erteilung 25.04.2019; Nachanmeldungen: WO

Permalink: https://www.hzdr.de/publications/Publ-31216
Publ.-Id: 31216


P1803 - Teilchenspektrometer und Teilchenspektrometrieverfahren

Klingner, N.; Wilhelm, R. A.

Die Erfindung betrifft ein Teilchenspektrometer und Teilchenspektrometrieverfahren zum Analysieren eines entlang eines Teilchenpfades verlaufenden Teilchenpulses, wobei der Teilchenpuls an einer Kreuzungsposition zur Überlagerung mit einem Photonenpuls gebracht wird, sodass ein Teil der Teilchen des Teilchenpulses mittels des Photonenpulses elektrisch umgeladen wird, und wobei anschließend mittels eines Analysators die umgeladenen Teilchen separiert und die umgeladenen oder die nicht umgeladenen Teilchen separat mittels eines Teilchendetektors detektiert werden.

  • Patent
    DE102018106412 - Offenlegung 26.09.2019

Permalink: https://www.hzdr.de/publications/Publ-31215
Publ.-Id: 31215


Magnetic phase diagram and magnetoelastic coupling of NiTiO3

Dey, K.; Sauerland, S.; Werner, J.; Scurschii, I.; Abdel-Hafiez, M.; Bag, R.; Singh, S.; Klingeler, R.

We report high-resolution dilatometry on high-quality single crystals of NiTiO3 grown by means of the optical floating-zone technique. The anisotropic magnetic phase diagram is constructed from thermal expansion and magnetostriction studies up toB=15 T and magnetization studies in static (15-T) and pulsed (60-T) magnetic fields. Our data allow us to quantitatively study magnetoelastic coupling and to determine uniaxial pressure dependencies. While the entropy changes are found to be of magnetic nature, Grüneisen analysis implies only one relevant energy scale in the whole low-temperature regime. Thereby, our data suggest that the observed structural changes due to magnetoelastic coupling and previously reported magnetodielectric coupling [L. Balhorn, J. Hazi, M. C. Kemei, and R. Seshadri, Phys. Rev. B93, 104404(2016)] are driven by the same magnetic degrees of freedom that lead to long-range magnetic order in NiTiO3.

Permalink: https://www.hzdr.de/publications/Publ-31214
Publ.-Id: 31214


Extremely slow nonequilibrium monopole dynamics in classical spin ice

Stöter, T.; Doerr, M.; Granovsky, S.; Rotter, M.; Goennenwein, S. T. B.; Zherlitsyn, S.; Petrenko, O. A.; Balakrishnan, G.; Zhou, H. D.; Wosnitza, J.

We report on the nonequilibrium monopole dynamics in the classical spin ice Dy2Ti2O7 detected by means of high-resolution magnetostriction measurements. Significant lattice changes occur at the transition from the kagome-ice to the saturated-ice phase, visible in the longitudinal and transverse magnetostriction. A hysteresis opening at temperatures below 0.6 K suggests a first-order transition between the kagome and saturated state. Extremely slow lattice relaxations, triggered by changes of the magnetic field, were observed. These latticerelaxation effects result from nonequilibrium monopole formation or annihilation processes. The relaxation times extracted from our experiment are in good agreement with theoretical predictions with decay constants of the order of 104 s at 0.3K.

Downloads:

Permalink: https://www.hzdr.de/publications/Publ-31213
Publ.-Id: 31213


Splitting of the magnetic monopole pair-creation energy in spin ice

Hornung, J.; Gottschall, T.; Opherden, L.; Antlauf, M.; Schwarz, M.; Kroke, E.; Herrmannsdörfer, T.; Wosnitza, J.

The thermodynamics in spin-ice systems are governed by emergent magnetic monopole excitations and, until now, the creation of a pair of these topological defects was associated with one specific pair-creation energy. Here, we show that the electric dipole moments inherent to the magnetic monopoles lift the degeneracy of their creation process and lead to a splitting of the pair-creation energy. We consider this finding to extend the model of magnetic relaxation in spin-ice systems and show that an electric dipole interaction in the theoretically estimated order of magnitude leads to a splitting which can explain the controversially discussed discrepancies between the measured temperature dependence of the magnetic relaxation times and previous theory. By applying our extended model to experimental data of, various spin-ice systems, we show its universal applicability and determine a dependence of the electric dipole interaction on the systemparameters, which is in accordance with the
theoretical model of electric dipole formation.

Permalink: https://www.hzdr.de/publications/Publ-31212
Publ.-Id: 31212


Fermi surface investigation of the noncentrosymmetric superconductor α-PdBi

Klotz, J.; Butcher, T.; Förster, T.; Hornung, J.; Sheikin, I.; Wisniewski, P.; Jesche, A.; Wosnitza, J.; Kaczorowski, D.

The noncentrosymmetric superconductor α-PdBi is a candidate material for the realization of topological superconductivity. Here, we present a detailed de Haas–van Alphen (dHvA) study together with band-structure calculations within the framework of density functional theory. The rich dHvA spectra are a manifestation of the 13 bands that cross the Fermi energy EF . We find excellent agreement between calculated and experimentally observed dHvA frequencies with moderately enhanced effective masses. One of the bands crossing EF, the so-called α band, exhibits topological character with Weyl nodes lying 43 meV below EF .

Downloads:

Permalink: https://www.hzdr.de/publications/Publ-31203
Publ.-Id: 31203


High-field magnetization study of (Nd,Dy)2Fe14B: Intrinsic properties and promising compositions

Kostychenko, N. V.; Tereshina, I. S.; Gorbunov, D.; Tereshina-Chitrova, E. A.; Rogacki, K.; Andreev, A. V.; Doerr, M.; Politova, G. A.; Zvezdin, A. K.

The crystal-electric field and exchange parameters are determined for the (Nd0.5Dy0.5)2Fe14B compound by analyzing experimental magnetization curves obtained in high magnetic fields up to 58 T. The series (NdxDy1-x)2Fe14B compounds were analyzed theoretically to achieve a temperature stability while maintaining a large maximum energy product (BH)max. We demonstrate that computational simulations is an important tool in the materials design.

Permalink: https://www.hzdr.de/publications/Publ-31202
Publ.-Id: 31202


Direct measurements of the magnetocaloric effect of Fe49Rh51 using the mirage effect

Amirov, A. A.; Cugini, F.; Kamantsev, A. P.; Gottschall, T.; Solzi, M.; Aliev, A. M.; Spichkin, Y. I.; Koledov, V. V.; Shavrov, V. G.

The magnetocaloric effect in the Fe49Rh51 alloy was systematically studied using three different approaches: in-field differential scanning calorimetry, standard direct measurement of the adiabatic temperature change, and a non-contact method based on a thermo-optical phenomenon, the mirage effect, which was able to directly test the magnetocaloric response induced by a fast magnetic field variation. The metamagnetic phase transition of Fe49Rh51 was studied in the temperature range of 290–330 K at magnetic fields up to 1.8 T through magnetic and calorimetric measurements. The estimated parameters of phase transition were comparable with the literature data. The values of adiabatic temperature change obtained with the three methods (calorimetry, standard direct measurement, and mirage-based technique), which explore three different time scales of the field variation (static field, 1 T s−1, 770 T s−1), were consistent, proving the absence of dynamic constraints in the first-order magnetostructural transition at the maximum field sweep rate.

Permalink: https://www.hzdr.de/publications/Publ-31201
Publ.-Id: 31201


Detection Efficacy of 18F-PSMA-1007 PET/CT in 251 Patients with Biochemical Recurrence of Prostate Cancer After Radical Prostatectomy

Giesel, F. L.; Knorr, K.; Spohn, F.; Will, L.; Maurer, T.; Flechsig, P.; Neels, O.; Schiller, K.; Amaral, H.; Weber, W.; Haberkorn, U.; Schwaiger, M.; Kratochwil, C.; Choyke, P.; Kramer, V.; Kopka, K.; Eiber, M.

Prostate-specific membrane antigen (PSMA)–targeted PET imaging recently emerged as a new method for the staging and restaging of prostate cancer. Most published studies investigated the diagnostic potential of 68Ga-labeled PSMA agents that are excreted renally 18F-PSMA-1007 is a novel PSMA ligand that has excellent preclinical characteristics and that is only minimally excreted by the urinary tract, a potential advantage for pelvic imaging. The aim of this study was to investigate the diagnostic efficacy of 18F-PSMA-1007 for biochemical recurrence (BCR) after radical prostatectomy. Methods: From 3 academic centers, 251 patients with BCR after radical prostatectomy were evaluated in a retrospective analysis. Patients who had received second-line androgen deprivation therapy (ADT) or chemotherapy were excluded, but prior first-line ADT exposure was allowed. The median prostate-specific antigen (PSA) level was 1.2 ng/mL (range, 0.2–228 ng/mL). All patients underwent PSMA PET/CT at 92 ± 26 min after injection of 301 ± 46 MBq of 18FPSMA-1007. The rate of detection of presumed recurrence sites was correlated with the PSA level and original primary Gleason score. A comparison to a subset of patients treated previously with ADT was undertaken. Results: Of the 251 patients, 204 (81.3%) had evidence of recurrence on 18F-PSMA-1007 PET/CT. The detection rates were 94.0% (79/84), 90.9% (50/55), 74.5% (35/47), and 61.5% (40/65) for PSA levels of greater than or equal to 2, 1 to less than 2, 0.5 to less than 1, and 0.2 to less than 0.5 ng/mL, respectively. 18FPSMA-1007 PET/CT revealed local recurrence in 24.7% of patients (n = 62). Lymph node metastases were present in the pelvis in 40.6% of patients (n = 102), in the retroperitoneum in 19.5% of patients (n = 49), and in supradiaphragmatic locations in 12.0% of patients (n = 30). Bone and visceral metastases were detected in 40.2% of patients (n = 101) and in 3.6% of patients (n = 9), respectively. In tumors with higher Gleason scores (≤7 vs. ≥8), detection efficacy trended higher (76.3% vs. 86.7%) but was not statistically significant (P = 0.32). However, detection efficacy was higher in patients who had received ADT (91.7% vs. 78.0%) within 6 mo before imaging (P = 0.0179). Conclusion: 18F-PSMA-1007 PET/CT offers high detection rates for BCR after radical prostatectomy that are comparable to or better than those published for 68Ga-labeled PSMA ligands.

Keywords: 18F-PSMA-1007; PET/CT; hybrid imaging; prostate cancer; biochemical recurrence

  • Lecture (Conference)
    Annual Congress of the European Association of Nuclear Medicine, October 13 – 17, 2018, Düsseldorf, Germany, 13.-17.10.2018, Düsseldorf, Deutschland
    DOI: 10.1007/s00259-018-4148-3

Permalink: https://www.hzdr.de/publications/Publ-31200
Publ.-Id: 31200


Laboratory Study of Bilateral Supernova Remnants and Continuous MHD Shocks

Mabey, P.; Albertazzi, B.; Rigon, G.; Marquès, J. R.; Palmer, C. A. J.; Topp-Mugglestone, J.; Perez-Martin, P.; Kroll, F.; Brack, F.-E.; Cowan, T.; Schramm, U.; Falk, K.; Gregori, G.; Falize, E.; Koenig, M.

Many supernova remnants (SNRs), such as G296.5+10.0, exhibit an axisymmetric or barrel shape. Such
morphologies have previously been linked to the direction of the Galactic magnetic field, although this remains
uncertain. These SNRs generate magnetohydrodynamic shocks in the interstellar medium, modifying its physical
and chemical properties. The ability to study these shocks through observations is difficult due to the small spatial
scales involved. In order to answer these questions, we perform a scaled laboratory experiment in which a lasergenerated
blast wave expands under the influence of a uniform magnetic field. The blast wave exhibits a spheroidal
shape, whose major axis is aligned with the magnetic field, in addition to a more continuous shock front. The
implications of our results are discussed in the context of astrophysical systems.

Keywords: Supernova remnants (1667); Shocks (2086); Magnetic fields (994); Astrophysical magnetism (102); Magnetohydrodynamics (1964); Galaxy magnetic fields (604); Interstellar magnetic fields (845)

Permalink: https://www.hzdr.de/publications/Publ-31198
Publ.-Id: 31198


High-Performance Bismuth-Doped Nickel Aerogel Electrocatalyst for the Methanol Oxidation Reaction

Dubale, A. A.; Zheng, Y.; Wang, H.; Hübner, R.; Li, Y.; Yang, J.; Zhang, J.; Sethi, N. K.; He, L.; Zheng, Z.; Liu, W.

Low-cost, non-noble-metal electrocatalysts are required for direct methanol fuel cells, but their development has been hindered by limited activity, high onset potential, low conductivity, and poor durability. A surface electronic structure tuning strategy is presented, which involves doping of a foreign oxophilic post-transition metal onto transition metal aerogels to achieve a non-noble-metal aerogel Ni97Bi3 with unprecedented electrocatalytic activity and durability in methanol oxidation. Trace amounts of Bi are atomically dispersed on the surface of the Ni97Bi3 aerogel, which leads to an optimum shift of the d-band center of Ni, large compressive strain of Bi, and greatly increased conductivity of the aerogel. The electrocatalyst is endowed with abundant active sites, efficient electron and mass transfer, resistance to CO poisoning, and outstanding performance in methanol oxidation. This work sheds light on the design of high-performance non-noble-metal electrocatalysts

Keywords: aerogels; bismuth dopants; methanol oxidation; nickel; single atoms

Permalink: https://www.hzdr.de/publications/Publ-31193
Publ.-Id: 31193


High PerformanceComputing: 35th International Conference, ISC High Performance 2020

Sadayappan, P.; Chamberlain, B. L.; Juckeland, G.; Ltaief, H.

This book constitutes the refereed proceedings of the 35th International Conference on High Performance Computing, ISC High Performance 2020, held in Frankfurt/Main, Germany, in June 2020.*

The 27 revised full papers presented were carefully reviewed and selected from 87 submissions. The papers cover a broad range of topics such as architectures, networks & infrastructure; artificial intelligence and machine learning; data, storage & visualization; emerging technologies; HPC algorithms; HPC applications; performance modeling & measurement; programming models & systems software.

*The conference was held virtually due to the COVID-19 pandemic.

Keywords: artificial intelligence; computer hardware; computer networks; computer programming; computer systems; distributed computer systems; microprocessor chips; parallel algorithms; parallel architectures; parallel processing

Permalink: https://www.hzdr.de/publications/Publ-31181
Publ.-Id: 31181


P1802 - Universal Building Blocks for Radiolabeling

Pietzsch, H.-J.; Walther, M.

The present invention describes novel chelators (multidentate ligands) and precompounds for complexation of radiometals and non-radioactive counterparts, for use in radiopharmacy. The invention includes a process and a kit involving such chelators.
Active moieties directing to a pharmaceutical target (such as peptides or proteins) can be attached to the chelator very easily via the so called “click-chemistry” forming a triazole-ring moiety. The aromatic triazole-nitrogen itself acts as a new and “soft” nucleophilic site enabling for complexation of various radiometals or non-radioactive counterparts. The chelators are capable of fast complexation at low temperature.

  • Patent
    PCT/EP2019/054954 - Offenlegung 06.09.2019; Nachanmeldungen: EP

Permalink: https://www.hzdr.de/publications/Publ-31180
Publ.-Id: 31180


P1801 - Method for the preparation of nanoscale DNA-encircled lipid bilayers

Fahmy, K.; TU Dresden

The present invention relates to a method for the preparation of nanoscale nucleic acid-encircled lipid bilayers, the nanoscale nucleic acid-encircled lipid bilayers and their use.

  • Patent
    PCT/EP2019/054271 - Offenlegung 29.08.2019; Nachanmeldungen: EP

Permalink: https://www.hzdr.de/publications/Publ-31179
Publ.-Id: 31179


P1714 - Verfahren zur Trennung von Mineralien

Babel, B. M.; Kupka, N.; Rudolph, M.

Die Erfindung betrifft ein Verfahren zur Trennung von Mineralien aus Mineralgemengen mittels Flotation unter Verwendung eines Drückers. Dabei ist vorgesehen, dass kolloidales Siliciumdioxid einem wässerigen, das Mineralgemenge enthaltenden Gemisch als Drücker zugesetzt wird.

  • Patent
    DE102017129673 - Erteilung 13.12.2018

Permalink: https://www.hzdr.de/publications/Publ-31178
Publ.-Id: 31178


P1713 - Verfahren zum Herstellen eines Probenpräparats, Probenpräparat und Verfahren zum Untersuchen eines Probenmaterials

Bartzsch, A.; Gilbricht, S.; Bachmann, K.; Heinig, T.

Die Erfindung betrifft ein Verfahren zum Herstellen eines Probenpräparats, ein Probenpräparat und ein Verfahren zum Untersuchen eines Probenmaterials, wobei das Probenpräparat zur Untersuchung eines granularen Probenmaterials dient und herstellbar ist, indem das granulare Probenmaterial mit einem flüssigen ersten Einbettmaterial vermengt wird, das Einbettmaterial unter Ausbildung eines Vorpräparats verfestigt wird und unter Ausbildung von Trennflächen in mehrere Teilstücke zertrennt wird, die Teilstücke mit mehreren Trennflächen in einer gemeinsamen Ebene liegend in einem flüssigen zweiten Einbettmaterial eingebettet werden, und das zweite Einbettmaterial verfestigt wird.

  • Patent
    DE102017128355 - Erteilung 17.01.2019

Permalink: https://www.hzdr.de/publications/Publ-31177
Publ.-Id: 31177


P1712 - Method for determining the level of molten magnesium in a titanium reduction cell

in Russian

Stefani, F.; Krauter, N.; Wondrak, T.; Gundrum, T.; Eckert, S.

FIELD: metallurgy. SUBSTANCE: invention relates to the metallurgy industry. Magnesium level and the skull characteristics in the titanium reduction reactor determining method, based on the EMF measurements in the receiving coil, induced by the electromagnetic field from located around the retort the exciting windings set, contains the steps, on which for the determination currents of different frequencies are used, at that, first, by the electrodynamics equations numerical solving, developing the reference base of the EMF calculated values in the located above the reactor receiving coil, with the molten magnesium different specified levels, different titanium skull given positions and sizes for the supply current given set of frequencies in the range of 1–50 Hz, and then, in the process of titanium reduction, with the same set of current parameters in the excitation coils, measuring the EMF values in the receiving coil, which are compared with the reference ones, and the least standard deviation is determined by the smallest standard deviation method, and the molten magnesium level, the titanium skull position and size are judged by it. EFFECT: increase in the molten metal level determining accuracy and the expansion in the method possibilities. 5 cl, 13 dwg

  • Patent
    RU2676845 - Erteilung 11.01.2019

Permalink: https://www.hzdr.de/publications/Publ-31176
Publ.-Id: 31176


P1711 - Peptid-Trägermaterialien als biofunktionalisierte Sammler

Lederer, F.; Pollmann, K.; Rudolph, M.

Die Erfindung betrifft ein Verfahren zur selektiven Abtrennung von Submikro- oder Mikropartikeln mittels eines biofunktionalisierten Sammlers, ein biofunktionalisierter Sammler umfassend mindestens ein selektiv bindendes Peptid, ein selektiv bindendes Peptid und die Verwendung eines Verfahrens oder eines biofunktionalisierten Sammlers zur Gewinnung oder Rückgewinnung von Submikro- oder Mikropartikeln.

  • Patent
    DE102017219800 - Offenlegung 09.05.2019

Permalink: https://www.hzdr.de/publications/Publ-31175
Publ.-Id: 31175


P1710 - 4-(Furan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-amin-Derivate und deren Verwendung

Moldovan, R.-P.; Lai, T. H.; Schröder, S.; Dukic-Stefanovic, S.; Deuther-Conrad, W.; Brust, P.; Fischer, S.; Ludwig, F.-A.

Die Erfindung betrifft eine Verbindung der allgemeinen Formel I worin eine Phenylgruppe oder eine Pyridylgruppe ist, R1 aus der Gruppe ausgewählt ist, die aus Wasserstoff, Halogen und -CN besteht; R2 aus der Gruppe ausgewählt ist, die aus Fluor, einer fluorierten Alkylgruppe mit 1 bis 12 Kohlenstoffatomen, einer fluorierten Alkoxygruppe mit 1 bis 12 Kohlenstoffatomen und einer fluorierten Ethergruppe besteht; Z -(CH2)n- oder -(CH2)m-C(O)-(CH2)p- ist, wobei n eine Ganzzahl von 1 bis 12 ist und wobei m und p gleich oder verschieden sein können und jeweils 0 oder eine Ganzzahl von 1 bis 12 sind.

  • Patent
    DE102017125533 - Offenlegung 02.05.2019; Nachanmeldungen: WO

Permalink: https://www.hzdr.de/publications/Publ-31174
Publ.-Id: 31174


P1709 - Vorrichtung und Verfahren zum Erzeugen von Ionenpulsen

Wilhelm, R. A.; Klingner, N.; Facsko, S.

Die Erfindung betrifft eine Vorrichtung und ein Verfahren zum Erzeugen von Ionenpulsen, insbesondere von ultrakurzen Ionenpulsen, wobei die Vorrichtung eine Vakuumkammer, eine in der Vakuumkammer angeordnete Kathode, einen Laser zum Erzeugen von Laserpulsen, die auf die Kathode auftreffen und aus dieser Elektronen herauslösen, eine erste Beschleunigungseinrichtung zum Beschleunigen der Elektronen unter Erzeugung von Ionenpulsen in ein Ionisationsvolumen, eine Zuführeinrichtung zum Zuführen einer zu ionisierenden Substanzen das Ionisationsvolumen und eine zweite Beschleunigungseinrichtung zum Beschleunigen der Ionen unter Ausbildung von Ionenpulsen aus dem Ionisationsvolumen heraus aufweist.

  • Patent
    DE102017218456 - Erteilung 22.11.2018

Permalink: https://www.hzdr.de/publications/Publ-31173
Publ.-Id: 31173


P1708 - Justiereinrichtung

Bartheld, U.

Die Erfindung betrifft eine Justiereinrichtung zur räumlichen Lageeinstellung eines Objekts (4), umfassend eine 10 Mehrzahl übereinander angeordneter Plattenelemente (11,12,13,14), die an einander zugewandten Seiten ineinandergreifende Radialführungsstrukturen (21,22) aufweisen, wobei auf einer Grundplatte (11) zumindest ein Paar von Verschiebungsplatten (12) und ein Paar von 15 Neigungsplatten (13) angeordnet sind, wobei Verschiebungsplatten (12) eine konstante Dicke aufweisen und ihre jeweilige obere Radialführungsstruktur (21) und untere Radialführungsstruktur (22) exzentrisch versetzt zueinander angeordnet sind und Neigungsplatten (13) eine variable Dicke 20 aufweisen und ihre jeweilige obere Radialführungsstruktur (21) und untere Radialführungsstruktur (22) konzentrisch zueinander angeordnet sind.

  • Patent
    DE102017123920 - Erteilung 20.12.2018; Nachanmeldungen: WO, US

Permalink: https://www.hzdr.de/publications/Publ-31172
Publ.-Id: 31172


P1707 - 3-Methylbenzo[e]imidazo[5,1-c][1,2,4]triazin-Derivate zur Verwendung als Inhibitoren von Phosphodiesterase 2A

Scheunemann, M.; Ritawidya, R.; Brust, P.; Schröder, S.

Die Erfindung betrifft eine Verbindung der allgemeinen Formel I oder ein pharmazeutisch akzeptables Salz davon, wobei A1, A2 und A3 unabhängig voneinander jeweils CH oder N sind; R1 -OR2 oder eine (3-Methyloxetan-3-yl)methyloxy-Gruppe ist, wobei R2 eine substituierte oder unsubstituierte Alkylgruppe mit 1 bis 12 Kohlenstoffatomen ist; X1 aus der Gruppe ausgewählt ist, die aus Wasserstoff, Halogen, Methyl -NO2 und einer kationischen Trialkylammoniumgruppe besteht; X2 aus der Gruppe ausgewählt ist, die aus Halogen, -NO2, einer Boronsäureester-Gruppe, einer Aryliodonium-Gruppe und einer spirocyclischen Iodoniumylid-Gruppe besteht, wobei die Boronsäureester-Gruppe eine Boronsäurepinakolester-Gruppe ist.

  • Patent
    DE102017119516 - Offenlegung 28.02.2019

Permalink: https://www.hzdr.de/publications/Publ-31171
Publ.-Id: 31171


P1705 - Wärmeübertrager

TU Dresden; Hampel, U.

Die Erfindung betrifft einen Wärmeübertrager mit wenigstens einer Trennwand und von wenigstens einer Seite der Trennwand abstehenden und die Oberfläche der Trennwand vergrößernden Oberflächenelementen, die von einem Fluid umströmbar sind. Es ist die Aufgabe der vorliegenden Erfindung, massearme Wärmeübertrager mit großer thermischer Übertragungsleistung vorzuschlagen. Diese Aufgabe wird durch einen Wärmeübertrager gelöst, bei dem die Oberflächenelemente flossenartig von der Trennwand abstehend ausgebildet sind und die Oberflächenelemente Verstärkungswülste aufweisen, wobei sich die Verstärkungswülste bis zu der Trennwand hin erstrecken.

  • Patent
    DE102017214261 - Offenlegung: 21.02.2019; Nachanmeldungen: WO, EP, JP, US

Permalink: https://www.hzdr.de/publications/Publ-31170
Publ.-Id: 31170


P1704 - Vorrichtung, Anordnung und Verfahren zum Charakterisieren der Torsion, der Rotation und/oder der Positionierung einer Welle

Buchenau, D.

Die Erfindung betrifft eine Vorrichtung, eine Anordnung und ein Verfahren zum Charakterisieren der Torsion, Rotation und/oder Positionierung einer Welle, wobei von einem zwischen mindestens zwei Magnetfelddetektoren angeordneten Magnetfelderzeuger mittels eines periodischen Erregersignals ein periodisches Magnetfeld erzeugt wird, das von der Welle modifiziert wird und an jedem der Magnetfelddetektoren ein Ausgangssignal hervorruft, wobei die amplitudenmäßige oder phasenmäßige Differenz zwischen dem Erregersignal und dem ersten Ausgangssignal als erste Messgröße und zwischen dem Erregersignal und dem zweiten Ausgangssignal als zweite Messgröße erfasst wird, die Summe und/oder die Differenz der ersten und der zweiten Messgröße gebildet wird, und basierend darauf die Torsion, Rotation und/oder Positionierung der Welle charakterisiert wird.

  • Patent
    DE102017111055 - Erteilung 06.09.2018; Nachanmeldungen: WO, CN, EP, US

Permalink: https://www.hzdr.de/publications/Publ-31169
Publ.-Id: 31169


P1703 - Schichtanordnung, elektronisches Bauteil mit einer Schichtanordnung und Verwendung einer Schichtanordnung

TU Bergakademie Freiberg; Rebohle, L.

Gemäß verschiedenen Ausführungsformen wird eine Schichtanordnung (100) bereitgestellt, welche Folgendes aufweist: eine erste Barriereschicht (102a) und eine zweite Barriereschicht (102b), wobei die beiden Barriereschichten (102a, 102b) elektrisch isolierend sind, und eine Schichtstruktur (110), welche zwischen den beiden Barriereschichten (102a, 102b) angeordnet ist und derart eingerichtet ist, dass diese mittels eines elektrischen Feldes einer ersten Polarität (311a) und mittels eines elektrischen Feldes einer der ersten Polarität entgegengesetzten zweiten Polarität (311b) remanent polarisierbar ist, wobei die Schichtstruktur (110) mindestens eine erste Ladungsspeicherschicht (104a), eine zweite Ladungsspeicherschicht (104b) und eine zwischen der ersten Ladungsspeicherschicht (104a) und der zweiten Ladungsspeicherschicht (104b) angeordnete elektrisch isolierende Tunnelbarriereschicht (106) aufweist.

  • Patent
    DE102017109082 - Offenlegung 31.10.2018

Permalink: https://www.hzdr.de/publications/Publ-31167
Publ.-Id: 31167


P1702 - Vorrichtung zum Charakterisieren des elektrischen Widerstandes eines Messobjekts

Kosub, T.; Makarov, D.

Die Erfindung betrifft eine Messvorrichtung zum Charakterisieren des elektrischen Widerstandes eines Messobjekts, aufweisend eine elektrische Energiequelle mit zwei Polen, eine Spannungsmesseinrichtung mit zwei Messeingängen, vier Anschlusskontakte zum Anschließen von vier Kontaktelektroden, und eine Schalteinrichtung zum variablen paarweisen elektrischen Verbinden je eines der Pole und Messeingänge mit je einem der Anschlusskontakte unter Ausbildung unterschiedlicher Beschaltungskonfigurationen, wobei die Messvorrichtung zum Durchführen von mindestens vier Messsequenzen mit unterschiedlichen Beschaltungskonfigurationen und zum Ermitteln des Längswiderstandes des Messobjekts unter Einbeziehung von in diesen Beschaltungskonfigurationen erfassten Strom- und Spannungssignalen ausgebildet ist.

  • Patent
    DE102017105317 - Erteilung 09.05.2018, Nachanmeldungen: WO, CN, EP, US

Permalink: https://www.hzdr.de/publications/Publ-31166
Publ.-Id: 31166


PIConGPU setup: Gas-foil target for ion acceleration

Pausch, R.; Levy, D.; Andriyash, I.; Schultze-Makuch, A.; Bernert, C.; Zeil, K.; Bussmann, M.; Kluge, T.; Garten, M.; Steiniger, K.; Debus, A.

This data set contains the PIConGPU source code used for the simulations presented in "Gas-foil target for ion acceleration" and the setup files.

Keywords: PIConGPU

  • Software in the HZDR data repository RODARE
    Publication date: 2020-06-18
    DOI: 10.14278/rodare.374
    License: GPL-3.0-only

Downloads:

Permalink: https://www.hzdr.de/publications/Publ-31165
Publ.-Id: 31165


P1701 - In vivo stable Hg-197(m) compounds, method for the production thereof and use thereof in nuclear medical diagnostics and endoradionuclide therapy (theranostics)

Pietzsch, H.-J.; Walther, M.; Wünsche, T.

The present invention relates to in vivo stable 197(m)Hg compounds according to formula (I) for use in nuclear medical diagnostics and endoradionuclide therapy (theranostics), particularly the treatment of cancer, a method for the production of the 197(m)Hg compounds comprising the step of radiolabeling of organic precursor compounds with NCA 197(m)Hg by electrophilic substitution; and the use of the 197(m)Hg compounds for nuclear medical diagnostics and endoradionuclide therapy (theranostics), particularly the treatment of cancer.

  • Patent
    PCT/EP2018/052996 - Offenlegung 16.08.2018, Nachanmeldungen: CA, EP, US

Permalink: https://www.hzdr.de/publications/Publ-31164
Publ.-Id: 31164


P1611 - Method and system for calibration-free determination of a flow velocity of an electrically conductive fluid

Krauter, N.; Stefani, F.; Eckert, S.; Gerbeth, G.

The present invention refers to a method and a system for calibration-free determination of a flow velocity of an electrically conductive fluid (7). Each of two field coils (1a, 1b), which are designed to be positioned at a distance from each other in the respective fluid (7) and electrically insulated from the respective fluid (7), is provided simultaneously with a pulsed electrical current, wherein the two pulsed electrical currents are oppositely directed, so that a primary magnetic field is created leading to oppositely directed eddy currents induced by the primary magnetic field in the surrounding fluid (7), thereby creating a secondary magnetic field in the respective fluid (7). The secondary magnetic field is measured after the pulsed electrical currents by two magnetic field sensors (3a, 3b), which are designed to be positioned at a distance from each other in the respective fluid (7) and electrically insulated from the respective fluid (7), wherein the flow velocity is calculated from a measured time-dependent strength of the secondary magnetic field and/or its time derivative.

  • Patent
    PCT/EP2016/076967 - Offenlegung 17.05.2018; Nachanmeldungen: EP

Permalink: https://www.hzdr.de/publications/Publ-31163
Publ.-Id: 31163


P1607 - Anordnung zum Charakterisieren des Füllstandes eines elektrisch leitfähigen Materials in einem Behälter

Zürner, T.; Ratajczak, M.; Wondrak, T.; Eckert, S.

Die Erfindung betrifft eine Anordnung zum Charakterisieren des Füllstandes eines elektrisch leitfähigen Materials in einem Behälter, aufweisend ein seitlich des Behälter-Innenraumes angeordnetes Sensorelement mit einer Erregerspule und zwei gradiometrisch verschalteten Empfängerspulen, wobei die Anordnung zum Beaufschlagen der Erregerspule mit einem Wechselstrom, zum Erfassen der an den gradiometrisch verschalteten Empfängerspulen resultierenden Ausgangsspannung, zum Ermitteln des Anteils der Ausgangsspannung ohne Phasenverschiebung zu dem Wechselstrom und/oder des Anteils der Ausgangsspannung mit einer Phasenverschiebung von 90° zu dem Wechselstrom, und zum Charakterisieren des Füllstandes basierend darauf ausgebildet ist.

  • Patent
    DE102016112266 - Offenlegung 11.01.2018

Permalink: https://www.hzdr.de/publications/Publ-31162
Publ.-Id: 31162


P1606 - Verfahren und Vorrichtung zu Ga-Rückgewinnung

FCM GmbH; TU Bergakademie Freiberg; Zeidler, O.

Die vorliegende Erfindung umfasst ein Verfahren zur selektiven Abtrennung von Ga aus Ätzabwässern mit Hilfe eines Dialyseverfahrens. Hierbei wird das besondere Komplexbildungsverhaltens des Ga ausgenutzt, welches einen instabilen Tetrahalogenokomplex bildet. Dieser bildet sich nur bei ausreichend hoher Halogenidkonzentration. Da die Halogenidkonzentration über die Membran niedriger wird, zerfällt der Ga-Tetrahalogenidokomplex in der Membran, wodurch das Ga zurückgehalten wird. Andere Metalle wie In und Fe zeigen dieses Verhalten nicht, weswegen die Tetrahalogenokomplexe dieser Metalle die Membran passieren können und somit selektiv abgetrennt werden können.

  • Patent
    DE102016210451 - Offenlegung 14.12.2017; Nachanmeldungen: TW, WO

Permalink: https://www.hzdr.de/publications/Publ-31161
Publ.-Id: 31161


P1605 - Verfahren und Trägermaterial zur Bereitstellung von metallionenbindenden Molekülen zur Gewinnung und Rückgewinnung von Wertmetallen

Matys, S.; Pollmann, K.; Raff, J.; Lehmann, F.

Die Erfindung betrifft ein Verfahren zur Bereitstellung von metallionenbindenden Molekülen basierend auf der Phagen-Display-Methode mittels eines planaren Trägermaterials mit immobilisierten Metallionen. Die Erfindung betrifft weiterhin ein planares Trägermaterial mit immobilisierten Metallionen, metallionenbindende Peptide erhältlich durch das erfindungsgemäße Verfahren sowie die Verwendung der metallionenbindenden Moleküle zur Gewinnung oder Rückgewinnung von Wertmetallen.

  • Patent
    DE102016208110 - Offenlegung 16.11.2017

Permalink: https://www.hzdr.de/publications/Publ-31160
Publ.-Id: 31160


P1604 - Verfahren und Mittel zum Betrieb eines komplementären analogen rekonfigurierbaren memristiven Widerstandsschalters sowie dessen Verwendung als künstliche Synapse

Du, N.; Li, K.; Schmidt, H.; Skorupa, I.

Die Erfindung betrifft ein Verfahren zum Betrieb eines elektronischen memristiven Bauelementes, welches aus einem komplementären analogen rekonfigurierbaren memristiven bidirektionalen Widerstandsschalter besteht, welcher eine Dreilagenschicht und zwei Elektroden aufweist. Das erfindungsgemäße Verfahren schlägt angepasste Schreibprozesse vor, die mittels der Überlagerung von Schreibpulssequenzen die Festlegung eines Zustandspaares komplementärer Widerstandszustände realisieren. In Verbindung mit Lesepulsen angepasster Polarität kann das elektronische memristive Bauelement Fuzzy-Logik umsetzen und als künstliche Synapse mit der Realisierung aller vier Lernkurven für komplementäres Lernen betrieben werden. Eine Mehrzahl von Verwendungsmöglichkeiten des erfindungsgemäß betriebenen Bauelementes wird vorgeschlagen.

  • Patent
    DE102016205860 - Offenlegung: 12.10.2017; Nachanmeldungen: WO, CN, US

Permalink: https://www.hzdr.de/publications/Publ-31159
Publ.-Id: 31159


Towards 3D-Motion Tracking of Instrumented Flow Followers in Large Vessels

Buntkiel, L.; Reinecke, S.; Hampel, U.

A concept for 3D-motion tracking of instrumented flow-following sensor particles, equipped with a gyroscope,
accelerometer, magnetometer and pressure sensor, has been developed. Consisting of an error
state Kalman filter (ESKF) the algorithm can track the attitude of the sensor particle in relation to a
reference coordinate system permanently, even under high acceleration, which interferes the attitude
estimation because it is based on measuring the gravitational acceleration. Experimental results show,
that using the ESKF for attitude estimation is giving accurate results even under high body acceleration.

Keywords: error state kalman filter; motion tracking; fluid dynamics; sensor particle; soft sensor

  • Open Access Logo Contribution to proceedings
    Sensor and Measurement Science International, 22.-25.06.2020, Nürnberg, Deutschland
    SMSI 2020 - Measurement Science, Hannover: AMA Service GmbH, 978-3-9819376-2-6, 309-310
    DOI: 10.5162/SMSI2020/E6.1

Downloads:

Permalink: https://www.hzdr.de/publications/Publ-31158
Publ.-Id: 31158


P1603 - Verfahren zur Herstellung von auf Silizium basierenden Anoden für Sekundärbatterien

TU Bergakademie Freiberg; Prucnal, S.; Skorupa, W.

Die Erfindung betrifft ein Verfahren zur Herstellung von auf Silizium basierenden Anoden für Sekundärbatterien, wobei die Sekundärbatterien zumindest aus der Anode, aus mindestens einem Elektrolyten und einer Gegenelektrode bestehen. Dabei werden folgende Schritte zur Herstellung einer Anode (20) durchgeführt:
– Abscheiden einer Silizium-Schicht (3) auf einem Korngrenzen (2) aufweisenden Metallsubstrat (1), wobei die Silizium-Schicht (3) zum Metallsubstrat (1) gerichtet eine erste Grenzfläche (14) aufweist,
– Beheizen des Metallsubstrats (1) mittels einer Heizeinheit (22) auf eine Temperatur zwischen 200°C und 1000°C,
– Tempern des Bereiches der dem Metallsubstrat (1) abgewandten zweiten Grenzfläche (15) der Silizium-Schicht (3) mittels einer energieintensiven Bestrahlung während der Beheizung,
– Erzeugen von Mehrphasen im Bereich der Silizium-Schicht (3) und des Metallsubstrats (1), bestehend aus amorphem Silizium und/oder kristallinem Silizium des Siliziums der Silizium-Schicht (3) und aus kristallinem Metall des Metallsubstrats (1) und aus Silizid und
– Erzeugen von kristallinem Metall des Metallsubstrats (1).

  • Patent
    DE102016001949 - Offenlegung 17.08.2017; Nachanmeldungen: WO, CN, EP, US

Permalink: https://www.hzdr.de/publications/Publ-31157
Publ.-Id: 31157


P1509 - Verfahren zum Aufarbeiten von Bleiglas und Elektronikschrott

TU Bergakademie Freiberg; Wolf, R.

Beschrieben wird ein Verfahren zum Aufarbeiten von Bleiglas und Elektronikschrott. Erfindungsgemäß umfasst dies die Schritte Zerkleinern und Vermischen des Bleiglases und des Elektronikschrottes zu einer Charge Aufschmelzen der Charge unter Zusatz einer oder mehrerer Verbindungen aus der Gruppe der Carbonate, Oxide und Hydroxide der Alkalimetalle und Reduktion des im Bleiglas enthaltenden Bleioxids durch ein Reduktionsmittel zu metallischem Blei unter Ausbildung einer Phase enthaltend eine Metallschmelze und einer Phase enthaltend eine Glasschmelze, wobei in der Glasschmelze die Konzentration von Alkalimetalloxiden im Bereich von 20 mol.-% bis 45 mol.-%
Erdalkalimetalloxiden im Bereich von 10 mol.-% bis 25 mol.-% Siliziumdioxid im Bereich von 40 mol.-% bis 50 mol.-% liegt, bezogen auf die Gesamtmenge an Alkalimetalloxiden, Erdalkalimetalloxiden und Siliziumdioxid in der Glasschmelze.

  • Patent
    DE102016220045 - Offenlegung: 19.04.2018

Permalink: https://www.hzdr.de/publications/Publ-31156
Publ.-Id: 31156


P1510 - Self-cleaning high temperature resistant solar selective coating

Abengoa Research S.L.; Lungwitz, F.; Neubert, M.

Estructura selectiva solar con autolimpieza resistente a altas temperaturas. La presente invención se dirige a una estructura formada por una sección superior que comprende una capa superior que comprende TiO2 dopado que presenta una alta transmitancia en el espectro visible y una alta reflectancia en la región IR y propiedades de autolimpieza, una sección intermedia absorbente y un sustrato. Debido a las propiedades mencionadas y a la resistencia a altas temperaturas, la estructura es útil como estructura selectiva solar para receptores de torre en sistemas de energía solar por concentración (CSP).

  • Patent
    ES2575746 - Offenlegung 30.06.2016; Nachanmeldungen: WO, EP

Permalink: https://www.hzdr.de/publications/Publ-31155
Publ.-Id: 31155


P1506 - Complementary resistance switch,contact-connected polycrystalline piezo-or ferroelectric thin-film layer,method for encrypting a bit sequence

You, T.; Schmidt, H.; Du, N.; Bürger, D.; Skorupa, I.

Disclosed is a complementary resistor switch (3) comprising two outer contacts, between which two piezo- or ferroelectric layers (11a and 11b) having an inner common contact are situated. At least one region (11', 11'') of the layers is modified, either the outer contacts are rectifying (S) and the inner contact is non-rectifying (0), or vice versa, the modified regions are formed at the rectifying contacts, the layers have different strain-dependent structural phases with different band gaps and/or different polarization charges, and the electrical conductivity of the layers is different. Also disclosed are a connectable resistor structure having at least one Schottky contact at two adjoining piezo- or ferroelectric layers, a polycrystalline piezo- or ferroelectric layer comprising modified crystallites, and a method and circuits for encrypting and decrypting a bit sequence.

  • Patent
    US20150364682 - Offenlegung 17.12.2015

Permalink: https://www.hzdr.de/publications/Publ-31154
Publ.-Id: 31154


New algorithm to discriminate phase distribution of gas-oil-water pipe flow with dual-modality wire-mesh sensor - Data set

de Assis Dias, F.; Nunes Dos Santos, E.; Da Silva, M. J.; Schleicher, E.; Morales, R. E. M.; Hewakandamby, B.; Hampel, U.

Data set used on the work "New Algorithm to Discriminate Phase Distribution of Gas-Oil-Water Pipe Flow with Dual-Modality Wire-Mesh Sensor".

Data were acquired using a dual-modality wire-mesh sensor designed by the Brazilian partner UTFPR. The experiments were performed at the University of Nottingham in a water-oil liquid-liquid flow loop.

However, the gas phase was introduced into the system to perform stratified three-phase flow measurements as a proof of concept. In this set of data, you find the calibrated amplitude and phase signals of nine points as well as permittivity and conductivity estimations (post-processing).

Keywords: complex impedance; flow visualization; gas-oil-water horizontal flow; three-phase; wire-mesh sensor


Related publications
New algorithm to discriminate phase distribution of … (Id 31145) has used this publication of HZDR-primary research data
  • Reseach data in the HZDR data repository RODARE
    Publication date: 2020-06-16
    DOI: 10.14278/rodare.372

Downloads:

Permalink: https://www.hzdr.de/publications/Publ-31152
Publ.-Id: 31152


The anomalous magnetic moment of the muon in the Standard Model

Aoyama, T.; Asmussen, N.; Benayoun, M.; Bijnens, J.; Blum, T.; Bruno, M.; Caprini, I.; Carloni Calame, C. M.; Cè, M.; Colangelo, G.; Curciarello, F.; Czyż, H.; Danilkin, I.; Davier, M.; Davies, C. T. H.; Della Morte, M.; Eidelman, S. I.; El-Khadra, A. X.; Gérardin, A.; Giusti, D.; Golterman, M.; Steven, G.; Gülpers, V.; Hagelstein, F.; Hayakawa, M.; Herdoíza, G.; Hertzog, D. W.; Hoecker, A.; Hoferichter, M.; Hoid, B.-L.; Hudspith, R. J.; Ignatov, F.; Izubuchi, T.; Jegerlehner, F.; Jin, L.; Keshavarzi, A.; Kinoshita, T.; Kubis, B.; Kupich, A.; Kupść, A.; Laub, L.; Lehner, C.; Lellouch, L.; Logashenko, I.; Malaescu, B.; Maltman, K.; Marinković, M. K.; Masjuan, P.; Meyer, A. S.; Meyer, H. B.; Mibe, T.; Miura, K.; Müller, S.; Nio, M.; Nomura, D.; Nyffeler, A.; Pascalutsa, V.; Passera, M.; Perez Del Rio, E.; Peris, S.; Portelli, A.; Procura, M.; Redmer, C. F.; Roberts, B. L.; Sánchez-Puertas, P.; Serednyakov, S.; Shwartz, B.; Simula, S.; Stöckinger, D.; Stöckinger-Kim, H.; Stoffer, P.; Teubner, T.; van de Water, R.; Vanderhaeghen, M.; Venanzoni, G.; von Hippel, G.; Wittig, H.; Zhang, Z.; Achasov, M. N.; Bashir, A.; Cardoso, N.; Chakraborty, B.; Chao, E.-H.; Charles, J.; Crivellin, A.; Deineka, O.; Denig, A.; Detar, C.; Dominguez, C. A.; Dorokhov, A. E.; Druzhinin, V. P.; Eichmann, G.; Fael, M.; Fischer, C. S.; Gámiz, E.; Gelzer, Z.; Green, J. R.; Guellati-Khelifa, S.; Hatton, D.; Hermansson-Truedsson, N.; Holz, S.; Hörz, B.; Knecht, M.; Koponen, J.; Kronfeld, A. S.; Laiho, J.; Leupold, S.; Mackenzie, P. B.; Marciano, W. J.; Mcneile, C.; Mohler, D.; Monnard, J.; Neil, E. T.; Nesterenko, A. V.; Ottnad, K.; Pauk, V.; Radzhabov, A. E.; de Rafael, E.; Raya, K.; Risch, A.; Rodríguez-Sánchez, A.; Roig, P.; San José, T.; Solodov, E. P.; Sugar, R.; Todyshev, K. Y.; Vainshtein, A.; Vaquero Avilés-Casco, A.; Weil, E.; Wilhelm, J.; Williams, R.; Zhevlakov, A. S.

We review the present status of the Standard Model calculation of the anomalous magnetic moment of the muon. This is performed in a perturbative expansion in the fine-structure constant α and is broken down into pure QED, electroweak, and hadronic contributions. The pure QED contribution is by far the largest and has been evaluated up to and including O(α5) with negligible numerical uncertainty. The electroweak contribution is suppressed by (m_μ/M_W)^2 and only shows up at the level of the seventh significant digit. It has been evaluated up to two loops and is known to better than one percent. Hadronic contributions are the most difficult to calculate and are responsible for almost all of the theoretical uncertainty. The leading hadronic contribution appears at O(α2) and is due to hadronic vacuum polarization, whereas at O(α3) the hadronic light-by-light scattering contribution appears. Given the low characteristic scale of this observable, these contributions have to be calculated with nonperturbative methods, in particular, dispersion relations and the lattice approach to QCD. The largest part of this review is dedicated to a detailed account of recent efforts to improve the calculation of these two contributions with either a data-driven, dispersive approach, or a first-principle, lattice-QCD approach. The final result reads a^{SM}_μ=116591810(43)×10^{−11} and is smaller than the Brookhaven measurement by 3.7σ. The experimental uncertainty will soon be reduced by up to a factor four by the new experiment currently running at Fermilab, and also by the future J-PARC experiment. This and the prospects to further reduce the theoretical uncertainty in the near future-which are also discussed here-make this quantity one of the most promising places to look for evidence of new physics.

Keywords: muon; g-2; anomalous magnetic moment

Downloads:

Permalink: https://www.hzdr.de/publications/Publ-31144
Publ.-Id: 31144


Towards Geostatistical Learning for the Geosciences: A Case Study in Improving the Spatial Awareness of Spectral Clustering

Talebi, H.; Peeters, L. J. M.; Mueller, U.; Tolosana Delgado, R.; van den Boogaart, K. G.

The particularities of geosystems and geoscience data must be understood before any development or implementation of statistical learning algorithms. Without such knowledge, the predictions and inferences may not be accurate and physically consistent. Accuracy, transparency and interpretability, credibility, and physical realism are minimum criteria for statistical learning algorithms when applied to the geosciences. This study briefly reviews several characteristics of geoscience data and challenges for novel statistical learning algorithms. A novel spatial spectral clustering approach is introduced to illustrate how statistical learners can be adapted for modelling geoscience data. The spatial awareness and physical realism of the spectral clustering are improved by utilising a dissimilarity matrix based on nonparametric higher-order spatial statistics. The proposed model-free technique can identify meaningful spatial clusters (i.e. meaningful geographical subregions) from multivariate spatial data at different scales without the need to define a model of co-dependence. Several mixed (e.g. continuous and categorical) variables can be used as inputs to the proposed clustering technique. The proposed technique is illustrated using synthetic and real mining datasets. The results of the case studies confirm the usefulness of the proposed method for modelling spatial data.

Keywords: Statistical learning; Spatial data; Spatial clustering; Higher-order spatial statistics; Geoscience data

Permalink: https://www.hzdr.de/publications/Publ-31143
Publ.-Id: 31143


Combined tumor plus nontumor interim FDG‐PET parameters are prognostic for response to chemoradiation in squamous cell esophageal cancer

Zschaeck, S.; Li, Y.; Bütof, R.; Lili, C.; Hua, W.; Troost, E.; Beck, M.; Amthauer, H.; Kaul, D.; Kotzerke, J.; Baur, A.; Ghadjar, P.; Baumann, M.; Krause, M.; Hofheinz, F.

We have investigated the prognostic value of two novel interim 18F‐fluorodeoxyglucose positron emission tomography (FDG‐PET) parameters in patients undergoing chemoradiation (CRT) for esophageal squamous cell carcinoma (ESCC): one tumor parameter (maximal standardized uptake ratio rSUR) and one normal tissue parameter (change of FDG uptake within irradiated nontumor‐affected esophagus ∆ SUVNTO). PET data of 134 European and Chinese patients were analyzed. Parameter establishment was based on 36 patients undergoing preoperative CRT plus surgery, validation was performed in 98 patients receiving definitive CRT. Patients received PET imaging prior and during fourth week of CRT. Clinical parameters, baseline PET parameters, and interim PET parameters (rSUR and ∆ SUVNTO) were analyzed and compared to event‐free survival (EFS), overall survival (OS), loco‐regional control (LRC) and freedom from distant metastases (FFDM). Combining rSUR and ∆ SUVNTO revealed a strong prognostic impact on EFS, OS, LRC and FFDM in patients undergoing preoperative CRT. In the definitive CRT cohort, univariate analysis with respect to EFS revealed several staging plus both previously established interim PET parameters as significant prognostic factors. Multivariate analyses revealed only rSUR and ∆ SUVNTO as independent prognostic factors (p = 0.003, p = 0.008). Combination of these parameters with the cutoff established in preoperative CRT revealed excellent discrimination of patients with a long or short EFS (73% vs . 17% at 2 years, respectively) and significantly discriminated all other endpoints (OS, p < 0.001; LRC, p < 0.001; FFDM, p = 0.02), even in subgroups. Combined use of interim FDG‐PET derived parameters ∆ SUVNTO and rSUR seems to have predictive potential, allowing to select responders for definitive CRT and omission of surgery.

Keywords: esophageal cancer; interim PET; standardized uptake ratio; normal tissue FDG uptake; chemoradiation; personalized treatment

Permalink: https://www.hzdr.de/publications/Publ-31142
Publ.-Id: 31142


Reconstructed spatial resolution and contrast recovery with Bayesian penalized likelihood reconstruction (Q.Clear) for FDG-PET compared to time-of-flight (TOF) with point spread function (PSF)

Rogasch, J.; Suleiman, S.; Hofheinz, F.; Bluemel, S.; Lukas, M.; Amthauer, H.; Furth, C.

Background

Bayesian penalized likelihood reconstruction for PET (e.g., GE Q.Clear) aims at improving convergence of lesion activity while ensuring sufficient signal-to-noise ratio (SNR). This study evaluated reconstructed spatial resolution, maximum/peak contrast recovery (CRmax/CRpeak) and SNR of Q.Clear compared to time-of-flight (TOF) OSEM with and without point spread function (PSF) modeling.

Methods

The NEMA IEC Body phantom was scanned five times (3 min scan duration, 30 min between scans, background, 1.5–3.9 kBq/ml F18) with a GE Discovery MI PET/CT (3-ring detector) with spheres filled with 8-, 4-, or 2-fold the background activity concentration (SBR 8:1, 4:1, 2:1). Reconstruction included Q.Clear (beta, 150/300/450), “PSF+TOF4/16” (iterations, 4; subsets, 16; in-plane filter, 2.0 mm), “OSEM+TOF4/16” (identical parameters), “PSF+TOF2/17” (2 it, 17 ss, 2.0 mm filter), “OSEM+TOF2/17” (identical), “PSF+TOF4/8” (4 it, 8 ss, 6.4 mm), and “OSEM+TOF2/8” (2 it, 8 ss, 6.4 mm). Spatial resolution was derived from 3D sphere activity profiles. RC as (sphere activity concentration [AC]/true AC). SNR as (background mean AC/background AC standard deviation).

Results

Spatial resolution of Q.Clear150 was significantly better than all conventional algorithms at SBR 8:1 and 4:1 (Wilcoxon, each p < 0.05). At SBR 4:1 and 2:1, the spatial resolution of Q.Clear300/450 was similar or inferior to PSF+TOF4/16 and OSEM+TOF4/16. Small sphere CRpeak generally underestimated true AC, and it was similar for Q.Clear150/300/450 as with PSF+TOF4/16 or PSF+TOF2/17 (i.e., relative differences < 10%). Q.Clear provided similar or higher CRpeak as OSEM+TOF4/16 and OSEM+TOF2/17 resulting in a consistently better tradeoff between CRpeak and SNR with Q.Clear. Compared to PSF+TOF4/8/OSEM+TOF2/8, Q.Clear150/300/450 showed lower SNR but higher CRpeak.

Conclusions

Q.Clear consistently improved reconstructed spatial resolution at high and medium SBR compared to PSF+TOF and OSEM+TOF, but only with beta = 150. However, this is at the cost of inferior SNR with Q.Clear150 compared to Q.Clear300/450 and PSF+TOF4/16/PSF+TOF2/17 while CRpeak for the small spheres did not improve considerably. This suggests that Q.Clear300/450 may be advantageous for the 3-ring detector configuration because the tradeoff between CR and SNR with Q.Clear300/450 was superior to PSF+TOF4/16, OSEM+TOF4/16, and OSEM+TOF2/17. However, it requires validation by systematic evaluation in patients at different activity and acquisition protocols.

Keywords: PET; Image reconstruction; Spatial resolution; Contrast recovery; Signal-to-noise ratio; TOF; PSF; Q.Clear; GE Discovery MI

Permalink: https://www.hzdr.de/publications/Publ-31141
Publ.-Id: 31141


Start-to-end simulations Modeling hybrid plasma accelerator experiments with PIConGPU

Pausch, R.; Bachmann, M.; Garten, M.; Hübl, A.; Steiniger, K.; Widera, R.; Kurz, T.; Schöbel, S.; Chang, Y.-Y.; Couperus Cabadağ, J. P.; Köhler, A.; Zarini, O.; Heinemann, T.; Ding, H.; Döpp, A.; Gilljohann, M. F.; Kononenko, O.; Raj, G.; Corde, S.; Hidding, B.; Karsch, S.; Assmann, R.; Martinez De La Ossa, A.; Irman, A.; Schramm, U.; Debus, A.

A brief summary of the evolution of LPWFA hybrid simulations and why start-to end simulations are needed to model the LPWFA setup.

Keywords: LPWFA; hybrid; PIConGPU

  • Lecture (Conference) (Online presentation)
    DMA meeting, 20.05.2020, Dresden, Deutschland

Permalink: https://www.hzdr.de/publications/Publ-31140
Publ.-Id: 31140


Nonlocal stimulation of three-magnon splitting in a magnetic vortex

Körber, L.; Schultheiß, K.; Hula, T.; Verba, R.; Faßbender, J.; Kakay, A.; Schultheiß, H.

We present a combined numerical, theoretical and experimental study on stimulated three-magnon splitting in a magnetic disk in the vortex equilibrium state. Our micromagnetic simulations and Brillouin-light-scattering results confirm that three-magnon splitting can be triggered even below threshold by exciting one of the secondary modes by magnons propagating in a waveguide next to the disk. The experiments show that stimulation is possible over an extended range of excitation powers and a wide range of frequencies around the eigenfrequencies of the secondary modes. Rate-equation calculations predict an instantaneous response to stimulation and the possibility to prematurely trigger three-magnon splitting even above threshold in a sustainable manner. These predictions are confirmed experimentally using time-resolved Brillouin-light-scattering measurements and are in a good qualitative agreement with the theoretical results. We believe that the controllable mechanism of stimulated three-magnon splitting could provide a possibility to utilize magnon-based nonlinear networks as hardware for reservoir or neuromorphic computing.

Here, we briefly describe how the archived data for the publication "Nonlocal stimulation of three-magnon splitting in a magnetic vortex", submitted to PRL, is structured.

"rate-equations"
- theoretical data of the temporal evolution of the spin wave modes in Fig. 4

"micromagnetic-simulation"
- MuMax3 simulation recipes (.go files) and sample-layout masks for the
simulations performed for Fig. 2(a,b,c).
- corresponding power spectra obtained with our "mumax3-pwsp" program
- mode profiles for stimulated and spontaneous splitting (Fig. 1(c) and Fig. 2(d))
- dispersion of the spin waves, calculated by micromagetnic simulation, shown in Fig. 1(b)

"experiments"
- electron beam microscopy image of the sample
- intensity spectrum of the waveguide, used to calculate the approximate
frequency/wave-vector region where the waveguide is effective (inset in Fig. 1(c))
- non-time-resolved BLS measurements, including spectra, power sweeps, etc. for
Figs 2,3 in "i3MS" folders, in more detail described by "i3MS_V1_KS_logbook.pdf"
- time-resolved BLS measurements, further explained in the corresponding subfolders
 

Keywords: spin wave; nonlinear; three-magnon splitting; stimulation; micromagnetic simulation; BLS


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Nonlocal stimulation of three-magnon splitting in a … (Id 31058) has used this publication of HZDR-primary research data
  • Reseach data in the HZDR data repository RODARE
    Publication date: 2020-06-11
    DOI: 10.14278/rodare.364
    License: CC-BY-4.0
    Embargo: 01.09.2020

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Permalink: https://www.hzdr.de/publications/Publ-31137
Publ.-Id: 31137


Local void fraction and pressure drop data for horizontal annular flow through orifice

Porombka, P.; Boden, S.; Lucas, D.; Hampel, U.

This dataset combines multiple measurements form air-water horizontal annular flow experiments in a pipe (case A) and a pipe with circular orifice with \(d^2 / D^2 = 0.6\)  (case B). Measurements where taken at superficial Reynolds numbers of Re=25000 for the gas phase and Re =4090 for the liquid phase. The following data are included for each case:

  • linear pressure drop between two points (case A), four points (case B) measured with split-range differential pressure transducers at 5Hz
  • time-averaged local liquid volume fraction distribution in cylindrical and Cartesian coordinates reconstructed from X-ray microtomography projections
  • reconstructed pipe axis coordinates and pipe radius
  • Python code to calculate secondary validation parameters (e.g. film thickness distribution) from primary data

The detailed 3D data is intended for validation of computational fluid dynamics codes based on phase-averaged variables such as the Euler-Euler approach.

Keywords: X-ray microtomography; film thickness; circular orifice; annular flow


Related publications
Horizontal annular flow through orifice studied by X-ray … (Id 30820) has used this publication of HZDR-primary research data
  • Reseach data in the HZDR data repository RODARE
    Publication date: 2020-06-09
    DOI: 10.14278/rodare.361

Downloads:

Permalink: https://www.hzdr.de/publications/Publ-31135
Publ.-Id: 31135


Olfactory dysfunction correlates with putaminal dopamine turnover in early de novo Parkinson’s disease

Löhle, M.; Wolz, M.; Beuthien-Baumann, B.; Oehme, L.; van den Hoff, J.; Kotzerke, J.; Reichmann, H.; Storch, A.

Although olfactory dysfunction is one of the most well-established prodromal symptoms in Parkinson’s disease (PD), its correlation with clinical disease progression or dopaminergic dysfunction still remains unclear. We here evaluated the association of striatal dopamine metabolism and olfactory function in a homogenous cohort of 30 patients with early untreated de novo PD. Striatal dopamine metabolism was assessed by the extended 18Fluorodopa PET scanning protocol to measure 18Fluorodopa uptake (Kocc) and the effective dopamine distribution volume ratio (EDVR) as the inverse of dopamine turnover. Olfactory function was estimated by the “Sniffin’ Sticks” test including odor threshold (T), discrimination (D) and identification (I) assessment. We detected moderate correlations of the EDVR in the posterior putamen with the TDI composite score (r = 0.412; p = 0.024; Pearson’s correlation test) and the odor identification score (r = 0.444; p = 0.014). These correlations were confirmed by multivariate regression analyses using age, sex, symptom duration and disease severity as measured by UPDRSIII motor score as candidate covariates. No other associations were observed between olfaction measures and Kocc and EDVR in all striatal regions. Together, olfactory dysfunction in early PD is not correlated with striatal 18Fluorodopa uptake as a measure for dopaminergic degeneration, but with putaminal dopamine turnover as a marker for dopaminergic presynaptic compensatory processes in early PD. These results should be treated as hypothesis generating and require confirmation by larger multicenter studies.

Permalink: https://www.hzdr.de/publications/Publ-31133
Publ.-Id: 31133


Predicting the dominating factors during heat transfer in magnetocaloric composite wires

Krautz, M.; Beyer, L.; Funk, A.; Waske, A.; Weise, B.; Freudenberger, J.; Gottschall, T.

Magnetocaloric composite wires have been studied by pulsed-field measurements up to μ0ΔH = 10 T with a typical rise time of 13 ms in order to evaluate the evolution of the adiabatic temperature change of the core, ΔTad, and to determine the effective temperature change at the surrounding steel jacket, ΔTeff, during the field pulse. An inverse thermal hysteresis is observed for ΔTad due to the delayed thermal transfer. By numerical simulations of application-relevant sinusoidal magnetic field profiles, it can be stated that for field-frequencies of up to two field cycles per second heat can be efficiently transferred from the core to the outside of the jacket. In addition, intense numerical simulations of the temperature change of the core and jacket were performed by varying different parameters, such as frequency, heat capacity, thermal conductivity and interface resistance in order to shed light on their impact on ΔTeff at the outside of the jacket in comparison to ΔTad provided by the core.

Permalink: https://www.hzdr.de/publications/Publ-31131
Publ.-Id: 31131


The influence of different artificial extracellular matrix implant coatings on the regeneration of a critical size femur defect in rats

Förster, Y.; Schulze, S.; Penk, A.; Neuber, C.; Möller, S.; Hintze, V.; Scharnweber, D.; Schnabelrauch, M.; Pietzsch, J.; Huster, D.; Rammelt, S.

Resorbable biomaterials based on artificial extracellular matrices (aECM) represent promising scaffolds for the treatment of large bone defects. Here, we investigated various glycosaminoglycan (GAG) derivatives of varying sulfation degree with respect to their influence on in vivo bone healing. The materials used in this study consisted of GAG-coated degradable polycaprolactone-co-lactide (PCL). Critical size femur defects in rats were filled with autologous bone serving as positive control or the respective coated or uncoated PCL scaffolds. After 2 and 12 weeks, progress in the healing process was investigated by analyzing the new bone matrix formation, the collagen content and hydroxyapatite formation by using micro-computed tomography (μCT), biomechanical testing, nuclear magnetic resonance spectroscopy (NMR) and histology. The sulfated GAG coating contributed substantially to bone regeneration, increased collagen synthesis and initiated mineralization of the organic matrix. Most substantial collagen production was detected in scaffolds coated with chondroitin sulfate. Scaffolds coated with hypersulfated hyaluronan induced formation of new bone volume comparable to what was observed in the positive control. GAG differing in the sugar backbone and degree of sulfation modulate the healing process at different times, eventually leading to improved bone healing.

Keywords: Artificial extracellular matrices; Glycosaminoglycans; Chondroitin sulfate; Sulfated hyaluronan; Bone healing

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  • Secondary publication expected from 05.06.2021

Permalink: https://www.hzdr.de/publications/Publ-31130
Publ.-Id: 31130


Characterization of blood coagulation dynamics and oxygenation in ex-vivo retinal vessels by fluorescence hyperspectral imaging

Podlipec, R.; Iztok, U.

The Mathematica software for the analysis of blood oxygenation in the intact or damaged retinal vessel from the fluorescence hyperspectral data using optimized two-component empirical asymmetric log-normal lineshape (LN) spectral model (Urbancic et al, Opt.
Express 21, 2013) modified with hemoglobin absorbance correction. 

  • Software in the HZDR data repository RODARE
    Publication date: 2020-06-03
    DOI: 10.14278/rodare.359
    License: CC-BY-4.0

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Permalink: https://www.hzdr.de/publications/Publ-31129
Publ.-Id: 31129


Compositional modelling of the impact of source lithology on the plant ionome

Pospiech, S.; van den Boogaart, K. G.; Tolosana Delgado, R.; Middleton, M.

The plant ionome is used for many applications for which it is important to understand and model how the elemental composition in the plants or plant organs evolved based on the available element sources, e.g. the effect of the soils or the underlying lithologies. Since the uptake and translocation of elements is influenced by a multitude of non-controllable parameters it is very challenging to relate a certain element pattern specifically to one parameter and quantify the effect of the parameter. Additionally, the applied modelling tools often do not take into account that both, the plant ionome and the element source, are multi-element concentrations. Concentrations are compositional data which represent the relative importance of some parts of a whole, and thus they are constrained and typically might suffer from problems of spurious correlations and negative bias, which disturbs our models of plant uptake.
In this contribution, we are presenting a statistical approach to describe the relation between geochemical composition of plants and the bedrock lithology while taking the multi-variate and constrained nature of concentrations into account. Modern compositional data analysis relies on log-ratio transforms and the Aitchison geometry. Most of the processes building the plant ionome from the element sources can be understood as linear modifications in the log-ratio space. A selective element transport would correspond to a shift of log-ratios. If this selectivity varies randomly this shift can be modelled by a multivariate normal distribution in log-ratio space. Selective element uptake by plants can thus be modelled by a downscaling of variability in the form of regression coefficients in log-ratio space. This allows to model many geochemical phenomena through a multivariate linear model in log-ratios.
To demonstrate the statistical method an exploration data set of lithologies and plant data from Northern Finland is used.

Keywords: plant geochemistry; ionome; compositional data; regression model; plant uptake; North Finland; gold mining; exploration

  • Open Access Logo Lecture (Conference) (Online presentation)
    Goldschmidt Virtual Conference 2020, 21.-26.06.2020, Online, USA

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Permalink: https://www.hzdr.de/publications/Publ-31128
Publ.-Id: 31128


Transport signatures of a junction between a quantum spin Hall System and a chiral topological superconductor

Novik, E. G.; Trauzettel, B.; Recher, P.

We investigate transport through a normal-superconductor (NS) junction made from a quantum spin Hall (QSH) system with helical edge states and a two-dimensional (2D) chiral topological superconductor (TSC) having a chiral Majorana edge mode. We employ a two-dimensional extended four-band model for HgTe-based quantum wells in a magnetic (Zeeman) field and subject to s-wave superconductivity. We show using the Bogoliubov-de Gennes scattering formalism that this structure provides a striking transport signal of a 2D TSC. As a function of the sample width (or Fermi energy) the conductance resonances go through a sequence of 2e2/h (nontrivial phase) and 4e2/h plateaux (trivial phase) which fall within the region of a nonzero Chern number (2D limit) as the sample width becomes large. These signatures are a manifestation of the topological nature of the QSH effect and the TSC.

Permalink: https://www.hzdr.de/publications/Publ-31127
Publ.-Id: 31127


Enhanced Ferromagnetism and Tunable Magnetism in Fe3GeTe2 Monolayer by Strain Engineering

Hu, X.; Zhao, Y.; Shen, X.; Krasheninnikov, A.; Chen, Z.; Sun, L.

Recent discovery of intrinsic ferromagnetism in Fe3GeTe2 (FGT) monolayer [Deng, Y.; et al. Nature 2018, 563, 94−99; Fei, Z.; et al. Nat. Mater. 2018, 17, 778−782] not only extended the family of two-dimensional (2D) magnetic materials but also stimulated further interest in the possibility to tune their magnetic properties without changing the chemical composition or introducing defects. By means of density functional theory computations, we explore strain effects on the magnetic properties of the FGT monolayer. We demonstrate that the ferromagnetism can be largely enhanced by the tensile strain in the FGT monolayer due to the competitive effects of direct exchange and superexchange interaction. The average magnetic moments of Fe atoms increase monotonically with an increase in biaxial strain from −5 to 5% in FGT monolayer. The intriguing variation of magnetic moments with strain in the FGT monolayer is related to the charge transfer induced by the changes in the bond lengths. Given the successful fabrication of the FGT monolayer, the strain-tunable ferromagnetism in the FGT monolayer can stimulate the experimental effort in this field. This work also suggests an effective route to control the magnetic properties of the FGT monolayer. The pronounced magnetic response toward the biaxial strain can be used to design the magnetomechanical coupling spintronics devices based on FGT.

Keywords: 2D materials; first-principles simulations

Permalink: https://www.hzdr.de/publications/Publ-31126
Publ.-Id: 31126


Simulating Raman spectra by combining first-principles and empirical potential approaches with application to defective MoS2

Kou, Z.; Hashemi, A.; Puska, M.; Krasheninnikov, A.; Komsa, H.-P.

Successful application of two-dimensional transition metal dichalcogenides in optoelectronic, catalytic, or sensing devices heavily relies on the materials’ quality, that is, the thickness uniformity, presence of grain boundaries, and the types and concentrations of point defects. Raman spectroscopy is a powerful and nondestructive tool to probe these factors but the interpretation of the spectra, especially the separation of different contributions, is not straightforward. Comparison to simulated spectra is beneficial, but for defective systems first-principles simulations are often computationally too expensive due to the large sizes of the systems involved. Here, we present a combined first-principles and empirical potential method for simulating Raman spectra of defective materials and apply it to monolayer MoS2 with random distributions of Mo and S vacancies. We study to what extent the types of vacancies can be distinguished and provide insight into the origin of different evolutions of Raman spectra upon increasing defect concentration. We apply to our simulated spectra the phonon confinement model used in previous experiments to assess defect concentrations, and show that the simplest form of the model is insufficient to fully capture peak shapes, but a good match is obtained when the type of phonon confinement and the full phonon dispersion relation are accounted for.

Keywords: Raman spectra; 2D materials; simulaitons

Permalink: https://www.hzdr.de/publications/Publ-31125
Publ.-Id: 31125


Two-Pion Intensity-Interferometry in Non-Central Collisions of Au + Au @ 1.23 A GeV

Greifenhagen, R.

High-statistics π-, π- and π+, π+ HBT data for non-central Au + Au collisions at 1.23 A GeV, measured with HADES at SIS18/GSI, are presented. The three-dimensional emission source is studied in dependence on pair transverse momentum and beam energy. A tilt of the source with respect to the reaction plane is observed. The spatial extension and the tilt magnitude of the source decrease with transverse momentum. A clear charge-sign difference is observed for the spatio-temporal variances, but not for the tilt angle of the source. Derived geometrical and temporal parameters do well complement the trend over several orders of magnitude in beam-energy provided that consistent transverse momenta are selected.

Keywords: femtoscopy; HBT

  • Contribution to proceedings
    XIV Workshop on Particle Correlations and Femtoscopy, 03.-07.06.2019, Dubna, Russian Federation
    Physics of Particles and Nuclei Volume 51, Issue 3, Berlin: Springer, 1063-7796, 288-292
    DOI: 10.1134/S1063779620030132

Permalink: https://www.hzdr.de/publications/Publ-31124
Publ.-Id: 31124


Origin of the metamagnetic transitions in Y1− xErxFe2(H,D)4.2 compounds

Paul-Boncour, V.; Isnard, O.; Shtender, V.; Scurschii, I.; Guillot, M.

The structural and magnetic properties of Y1−xErxFe2 intermetallic compounds and their hydrides and deuterides Y1−xErxFe2H(D)4.2 have been investigated using X-ray diffraction and magnetic measurements under static and pulsed magnetic field up to 60 T. The intermetallics crystallize in the C15 cubic structure (Fd-3m space group), whereas corresponding hydrides and deuterides crystallize in a monoclinic structure (Pc space group). All compounds display a linear decrease of the unit cell volume versus Er concentration; the hydrides have a 0.8% larger cell volume compared to the deuterides with same Er content. They are ferrimagnetic at low field and temperature with a compensation point at x=0.33 for the intermetallics and x=0.57 for the hydrides and deuterides. A sharp first order ferromagnetic-antiferromagnetic (FM-AFM) transition is observed upon heating at TFM−AFM for both hydrides and deuterides. These compounds show two different types of field induced transitions, which have different physical origin. At low temperature (T < 50 K), a forced ferri-ferromagnetic metamagnetic transition with Btrans1 ≈8 T, related to the change of the Er moments orientation from antiparallel to parallel Fe moment, is observed. Btrans1 is not sensitive to Er concentration, temperature and isotope effect. A second metamagnetic transition resulting from antiferromagnetic to ferrimagnetic state is also observed. The transition field Btrans2 increases linearly versus temperature and relates to the itinerant electron metamagnetic behavior of the Fe sublattice. An onset temperature TM0 is obtained by extrapolating TFM−AFM (B) at zero field. TM0 decreases linearly versus the Er content and is 45 ± 5 K higher for the hydrides compared to the corresponding deuteride. The evolution of TM0 versus cell volume shows that it cannot be attributed exclusively to a pure volume effect and that electronic effects should also be considered.

Permalink: https://www.hzdr.de/publications/Publ-31123
Publ.-Id: 31123


Germetry dependent beam dynamics of a 3.5-cell SRF Ggun cavity at ELBE

Zhou, K.; Arnold, A.; Teichert, J.; Xiang, R.; Ma, S.; Schaber, J.

In order to optimize the next generation SRF gun at HZDR ELBE radiation source, the impact on beam dynamics from the SRF cavity geometry needs to be investigated. This paper presents an analysis on the electromagnetic fields and output electron beam qualities, by changing the geometry parameters of a 3.5-cell SRF gun cavity. The simulation results show the higher electric field ratio in the first half cell to the TESLA like cell, the better beam parameters we can obtain, which, however, will also lead to a higher Emax/E0 and Bmax/E0.

Keywords: SRF gun; superconducting cavity

  • Open Access Logo Poster
    The 19th International Conference on RF Superconductivity(SRF2019), 30.06.-05.07.2019, Dresden, Germany
    DOI: 10.18429/JACoW-SRF2019-THP082
  • Open Access Logo Contribution to proceedings
    The 19th International Conference on RF Superconductivity(SRF2019), 30.06.-05.07.2019, Dresden, Germany
    Proceedings of the 19th International Conference on RF Superconductivity: JACoW, 978-3-95450-211-0
    DOI: 10.18429/JACoW-SRF2019-THP082

Permalink: https://www.hzdr.de/publications/Publ-31122
Publ.-Id: 31122


Raw data: Quantification of peptide-particle interactions: A phage mimicking approach via site-selective immobilization on glass

Schrader, M.

This set contains the raw data of the fluorescence scanning experiments used in the publication of Quantification of peptide-particle interactions: A phage mimicking approach via site-selective immobilization on glass


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Quantification of peptide-particle interactions: A phage … (Id 31119) has used this publication of HZDR-primary research data
  • Reseach data in the HZDR data repository RODARE
    Publication date: 2020-06-05
    DOI: 10.14278/rodare.357
    License: CC-BY-4.0

Downloads:

Permalink: https://www.hzdr.de/publications/Publ-31121
Publ.-Id: 31121


SRF Gun and SRF Linac Driven THz at ELBE Successfully in User Operation

Xiang, R.; Arnold, A.; Evtushenko, P.; Kovalev, S.; Lehnert, U.; Lu, P.; Ma, S.; Michel, P.; Murcek, P.; Ryzhov, A.; Schaber, J.; Schneider, C.; Teichert, J.; Vennekate, H.; Will, I.

The first all-SRF accelerator driven THz source has been operated as a user facility since 2018 at ELBE radiation center. The CW electron beam is extracted from SRF gun II, accelerated to relativistic energies and compressed to sub-ps length in the ELBE SRF linac with a chicane. THz pulses are produced by passing the short electron bunches through a diffraction radiator (CDR) and an undulator. The coherent THz power increases quadratically with bunch charge. The pulse energy up to 10 μJ at 0.3 THz with 100 kHz has been generated.

Keywords: all-SRF accelerator; THz user facility; CW electron beam; SRF gun

  • Open Access Logo Poster
    The 19th International Conference on RF Superconductivity(SRF2019), 30.06.-05.07.2019, Dresden, Germany
    DOI: 10.18429/JACoW-SRF2019-THP032
  • Open Access Logo Contribution to proceedings
    The 19th International Conference on RF Superconductivity(SRF2019), 30.06.-05.07.2019, Dresden, Germany
    Proceedings of the 19th International Conference on RF Superconductivity: JACoW, 978-3-95450-211-0
    DOI: 10.18429/JACoW-SRF2019-THP032

Permalink: https://www.hzdr.de/publications/Publ-31120
Publ.-Id: 31120


Preliminary geometry optimization of a 3.5-cell SRF Gun cavity at ELBE based on beam dynamics

Zhou, K.; Li, P.; Arnold, A.; Schaber, J.; Xiang, R.; Teichert, J.; Ma, S.

At present, ELBE radiation source at HZDR is optimizing the SRF cavity for the next generation ELBE SRF GUN. This paper presents a preliminary study on the geometry optimization of a 3.5-cell SRF gun cavity based on beam dynamics. By changing the lengths of the half cell and the first TESLA like cell, two new cavity models with higher electric field in the half cell are built and their RF fields are compared with SRF GUN I and SRF GUN II. Through the scanning of the RF phases and the electric fields, the simulation results indicate that new models have smaller transverse emittance at relatively lower electric field gradients and better performance on longitudinal emittance than SRF GUN I and SRF GUN II.

Keywords: SRF cavity; SRF gun; transverse emittance

  • Open Access Logo Poster
    39th International Free-Electron Laser Conference (FEL19), 26.-30.08.2019, Hamburg, Germany
  • Open Access Logo Contribution to proceedings
    39th International Free-Electron Laser Conference (FEL19), 26.-30.08.2019, Hamburg, Germany
    Proceedings of the 39th International Free-Electron Laser Conference: JACoW, 978-3-95450-210-3
    DOI: 10.18429/JACoW-FEL2019-WEP026

Permalink: https://www.hzdr.de/publications/Publ-31117
Publ.-Id: 31117


Metal and semiconductor photocathodes in HZDR SRF gun

Xiang, R.; Arnold, A.; Murcek, P.; Teichert, J.; Schaber, J.

Quality of photocathode in a photoinjector is one of the critical issues for the stability and reliability of the whole accelerator facility. In April 2013, the IR FEL lasing was demonstrated for the first time with the electron beam from the SRF gun with Cs2Te at HZDR. Cs2Te photocathode worked in SRF gun-I for more than one year without degradation. Currently, Mg photocathodes with QE up to 0.5% are applied in SRF Gun-II, generating e- beam with bunch charge up to 300 pC in CW mode with sub-ps bunch length for the high power THz radiation. It is an excellent demonstration that SRF guns can work reliably in a high power user facility.

Keywords: photocathode; Cs2Te; Mg; photoinjector; SRF gun

  • Invited lecture (Conferences)
    ICFA Advanced Beam Dynamics Workshop on Energy Recovery Linacs (ERL’19), 15.-20.09.2019, Berlin, Germany

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Permalink: https://www.hzdr.de/publications/Publ-31116
Publ.-Id: 31116


Robust Mg cathodes in SRF gun II

Xiang, R.; Jochen, T.

we present here the status of ELBE SRF gun II and the application of Mg photocathodes in SRF gun. In order to improve the QE of Mg cathodes, we appy the ps- UV laser cleaning for bulk Mg photocathodes. Furthermore, several alternative preparation methods of Mg are also under studying.

Keywords: Mg photocathode; SRF gun; laser cleaning

  • Open Access Logo Invited lecture (Conferences)
    European Workshop on Photocathodes for Particle Accelerator Applications (EWPAA 2019), 11.-13.09.2019, Villigen PSI, Switzerland

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Permalink: https://www.hzdr.de/publications/Publ-31115
Publ.-Id: 31115


Development and Implementation of Beam-Based Feedback Algorithms for Continuous Wave Superconducting Linear Accelerators

Maalberg, A.; Zenker, K.; Schwarz, A.; Evtushenko, P.; Kuntzsch, M.

The superconducting linear accelerator ELBE at Helmholtz-Center Dresden-Rossendorf is a versatile light source operated in continuous wave mode. New experiments and beam modes have a higher demand on the beam stability and reproducibility of accelerator settings. These requirements are addressed by an upgrade of the existing digital MicroTCA.4 based LLRF control by a beam-based feedback scheme. This poster gives an overview of the current control scheme, presents the planned beam diagnostics and discusses the possible ways of incorporating the beam-based feedback at the ELBE facility and a future light source.

  • Open Access Logo Poster
    19th International Conference on RF Superconductivity, 04.07.2019, Dresden, Germany

Permalink: https://www.hzdr.de/publications/Publ-31114
Publ.-Id: 31114


Spectral and spatial shaping of laser-driven proton beams using a pulsed high-field magnet beamline

Brack, F.-E.; Kroll, F.; Gaus, L.; Bernert, C.; Beyreuther, E.; Cowan, T.; Karsch, L.; Kraft, S.; Kunz-Schughart, L. A.; Leßmann, E.; Metzkes-Ng, J.; Obst-Hübl, L.; Pawelke, J.; Rehwald, M.; Schlenvoigt, H.-P.; Schramm, U.; Sobiella, M.; Rita Szabó, E.; Ziegler, T.; Zeil, K.

ntense laser-driven proton pulses, inherently broadband and highly divergent, pose a challenge to established beamline concepts on the path to application-adapted irradiation field formation, particularly for 3D. Here we experimentally show the successful implementation of a highly efficient (50% transmission) and tuneable dual pulsed solenoid setup to generate a homogeneous (laterally and in depth) volumetric dose distribution (cylindrical volume of 5 mm diameter and depth) at a single pulse dose of 0.7 Gy via multi-energy slice selection from the broad input spectrum. The experiments were conducted at the Petawatt beam of the Dresden Laser Acceleration Source Draco and were aided by a predictive simulation model verified by proton transport studies. With the characterised beamline we investigated manipulation and matching of lateral and depth dose profiles to various desired applications and targets. Using an adapted dose profile, we performed a first proof-of-technical-concept laser-driven proton irradiation of volumetric in-vitro tumour tissue (SAS spheroids) to demonstrate concurrent operation of laser accelerator, beam shaping, dosimetry and irradiation procedure of volumetric biological samples.

Keywords: Laser acceleration; Radiobiology; High field pulsed magnets

Permalink: https://www.hzdr.de/publications/Publ-31113
Publ.-Id: 31113


The attempt of using GaN as a photocathode in SRF Gun II

Schaber, J.; Xiang, R.; Teichert, J.; Arnold, A.; Murcek, P.; Zwartek, P.; Ma, S.

The photocathodes determine the beam quality in linear accelerators and represent a key component for many accelerator projects. Free-electron lasers (FEL), synchrotron- and THz radiation sources require injector systems with high brightness electron beams.

High quantum efficiency, a long lifetime and good vacuum stability, fast response time and low thermal emittance are desirable parameters for a perfect photocathode used in accelerators. Semiconductors such as GaN and GaAs as novel materials for photocathodes are showing an enormous potential.
GaAs is a well-known material for photocathodes. After activation with caesium and oxygen, it has a high QE for visible light (red or green). An advantage of GaAs is the opportunity of the layers to emit spin-polarized electrons.
GaN is a semi-conductive material and well known for its high QE when lighted with UV light. For improving the QE only caesium for activation is required.
At the moment GaN is used for photocathode-based detectors such as photomultipliers or phototubes and for LEDs. They have characteristics of low dark current, high-speed response and high sensitivity. It is very new for application in SRF Guns. It seems to be more robust and achieves higher QE than other photocathodes [1].
GaN is a semi-conductive material that is well known for its high QE when lighted with UV light. For improving the QE only caesium for activation is required. It has also a wide wavelength range from 100 to 380 nm.

Doping elements for n-type is silicon (Si) and for p-type magnesium (Mg). Mostly p-doped GaN promises better conditions because magnesium atoms increase the minority carrier diffusion length (about 200 nm). MOVPE is the most used technique to produce p-type GaN. Low temperatures are required in comparison to undoped or n-type GaN. Afterwards an annealing process is necessary to remove magnesium-bonded hydrogen. In p-type GaN electron are the minority carriers whereas holes are the majority carriers. The doping is assumed to lower the band bending around the surface. Therefore, the vacuum level is shifted to lower energy than the conductive band minimum in the flat band region.
Activated with a thin alkali metal layer, like caesium, GaN has the ability to lower the surface work function to produce a negative electron affinity (NEA). This effect originates from the surface band bending. Electrons excite over the bandgap and can easily enter into the vacuum.

Crystallinity and surface parameters define the photoemission properties. Modern analytical methods are used for identification of impurities, dislocations and characterization of the crystallinity of the semiconductors and the right cleaning treatment as well as the right caesium rating.
Like caesium telluride cathode it is possible to recover GaN(Cs) about 50% of the original QE with a simple bake out of 200°C and doing a Cs-reactivation to recover the degraded
cathode [2].
A big advantage of visible light cathodes instead of UV cathodes is to relax the drive laser requirements.

[1] Uchiyama, Shoichi et al. 2011. “GaN-Based Photocathodes with Extremely High Quantum Efficiency” 103511(2005):1–4.
[2] Siegmund, O. et al. 2006. “Development of GaN Photocathodes for UV Detectors.” 567:89–92

Keywords: GaN(Cs) photocathode; III-V semiconductor; NEA photocathode; thin layer deposition

  • Open Access Logo Lecture (Conference)
    ECASIA 2019-European Conference on Applications of Surface and Interface Analysis, 15.-20.09.2019, Dresden, Deutschland

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Permalink: https://www.hzdr.de/publications/Publ-31112
Publ.-Id: 31112


The attempt of using GaN(Cs) in SRF injector

Schaber, J.; Xiang, R.; Teichert, J.; Murcek, P.; Zwartek, P.; Arnold, A.; Ma, S.

The photocathodes determine the beam quality in linear accelerators and represent a key component for many accelerator projects. Free-electron lasers (FEL), synchrotron- and THz radiation sources require injector systems with high brightness electron beams.

High quantum efficiency, a long lifetime and good vacuum stability, fast response time and low thermal emittance are desirable parameters for a perfect photocathode used in accelerators. Semiconductors such as GaN and GaAs as novel materials for photocathodes are showing an enormous potential.
GaAs is a well-known material for photocathodes. After activation with caesium and oxygen, it has a high QE for visible light (red or green). An advantage of GaAs is the opportunity of the layers to emit spin-polarized electrons.
GaN is a semi-conductive material and well known for its high QE when lighted with UV light. For improving the QE only caesium for activation is required.
At the moment GaN is used for photocathode-based detectors such as photomultipliers or phototubes and for LEDs. They have characteristics of low dark current, high-speed response and high sensitivity. It is very new for application in SRF Guns. It seems to be more robust and achieves higher QE than other photocathodes [1].
Crystallinity and surface parameters define the photoemission properties. Modern analytical methods are used for identification of impurities, dislocations and characterization of the crystallinity of the semiconductors and the right cleaning treatment as well as the right caesium rating.
[1] Uchiyama, Shoichi et al. 2011. “GaN-Based Photocathodes with Extremely High Quantum Efficiency” 103511(2005):1–4.

Keywords: GaN; NEA activation; photocathode; thin layer deposition

  • Open Access Logo Poster
    EWPAA 2019: European workshop on photocathodes for particle accelerator applications, 11.-13.09.2019, Villingen, Schweiz

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Permalink: https://www.hzdr.de/publications/Publ-31109
Publ.-Id: 31109


The attempt of using GaN (Cs) as a photocathode in SRF injector

Schaber, J.; Xiang, R.; Teichert, J.; Arnold, A.; Murcek, P.; Zwartek, P.; Ma, S.

The photocathodes determine the beam quality in linear accelerators and represent a key component for many accelerator projects. Free-electron lasers (FEL), synchrotron- and THz radiation sources require injector systems with high brightness electron beams.

High quantum efficiency, a long lifetime and good vacuum stability, fast response time and low thermal emittance are desirable parameters for a perfect photocathode used in accelerators. Semiconductors such as GaN and GaAs as novel materials for photocathodes are showing an enormous potential.
GaAs is a well-known material for photocathodes. After activation with caesium and oxygen, it has a high QE for visible light (red or green).
An advantage of GaAs is the opportunity of the layers to emit spin-polarized electrons.
GaN is a semi-conductive material and well known for its high QE when lighted with UV light. For improving the QE only caesium for activation is required.
At the moment GaN is used for photocathode-based detectors such as photomultipliers or phototubes and for LEDs. They have characteristics of low dark current, high-speed response and high sensitivity. It is very new for application in SRF Guns. It seems to be more robust and achieves higher QE than other photocathodes [1].
Crystallinity and surface parameters define the photoemission properties. Modern analytical methods are used for identification of impurities, dislocations and characterization of the crystallinity of the semiconductors and the right cleaning treatment as well as the right caesium rating.
[1] Uchiyama, Shoichi et al. 2011. “GaN-Based Photocathodes with Extremely High Quantum Efficiency” 103511(2005):1–4.

Keywords: photocathode; semiconductor; NEA activation; surface analysis

  • Open Access Logo Poster
    DPG Frühjahrstagung, 18.-22.03.2019, München, Deutschland

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Permalink: https://www.hzdr.de/publications/Publ-31107
Publ.-Id: 31107


The attempt of using GaN as a photocathode in SRF Gun II

Schaber, J.; Xiang, R.; Murcek, P.; Arnold, A.; Teichert, J.; Ma, S.; Zwartek, P.

The photocathodes determine the beam quality in linear accelerators and represent a key component for many accelerator projects. Free-electron lasers (FEL), synchrotron- and THz radiation sources require injector systems with high brightness electron beams.

High quantum efficiency, a long lifetime and good vacuum stability, fast response time and low thermal emittance are desirable parameters for a perfect photocathode used in accelerators. Semiconductors such as GaN and GaAs as novel materials for photocathodes are showing an enormous potential.
GaAs is a well-known material for photocathodes. After activation with caesium and oxygen, it has a high QE for visible light (red or green). An advantage of GaAs is the opportunity of the layers to emit spin-polarized electrons.
GaN is a semi-conductive material and well known for its high QE when lighted with UV light. For improving the QE only caesium for activation is required.
At the moment GaN is used for photocathode-based detectors such as photomultipliers or phototubes and for LEDs. They have characteristics of low dark current, high-speed response and high sensitivity. It is very new for application in SRF Guns. It seems to be more robust and achieves higher QE than other photocathodes [1].
Crystallinity and surface parameters define the photoemission properties. Modern analytical methods are used for identification of impurities, dislocations and characterization of the crystallinity of the semiconductors and the right cleaning treatment as well as the right caesium rating.
[1] Uchiyama, Shoichi et al. 2011. “GaN-Based Photocathodes with Extremely High Quantum Efficiency” 103511(2005):1–4.

  • Open Access Logo Lecture (Conference)
    5. Annual MT Meeting, 04.-07.03.2019, Jena, Deutschland

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Permalink: https://www.hzdr.de/publications/Publ-31106
Publ.-Id: 31106


KLOE hadronic cross section data in the HepDATA repository

Müller, S.

Presentation at (remote) Kick-Off-Meeting of the PrecisionSM-Working group of the STRONG2020 EU Project.

Keywords: KLOE; HEPdata

  • Open Access Logo Lecture (Conference) (Online presentation)
    Kick-Off meeting for PrecisionSM working group of STRONG2020 project, 03.06.2020, ZOOM (Sweden), Sweden

Permalink: https://www.hzdr.de/publications/Publ-31105
Publ.-Id: 31105


Dataset for dynamic simulation of the CEFR control rod drop experiments

Fridman, E.

Dataset for dynamic simulation of the CEFR control rod drop experiments 


Related publications
Dynamic simulation of the CEFR control rod drop … (Id 31096) has used this publication of HZDR-primary research data
  • Reseach data in the HZDR data repository RODARE
    Publication date: 2020-06-03
    DOI: 10.14278/rodare.353

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Permalink: https://www.hzdr.de/publications/Publ-31104
Publ.-Id: 31104


ESFR-SMART WP1.2.1 dataset

Fridman, E.

ESFR-SMART WP1.2.1 dataset


Related publications
Neutronic analysis of the European Sodium Fast Reactor … (Id 31098) has used this publication of HZDR-primary research data
Neutronic analysis of the European Sodium Fast Reactor … (Id 31097) has used this publication of HZDR-primary research data
  • Reseach data in the HZDR data repository RODARE
    Publication date: 2020-06-03
    DOI: 10.14278/rodare.351

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Permalink: https://www.hzdr.de/publications/Publ-31102
Publ.-Id: 31102


Helmholtz AI For Matter at Helmholtz-Zentrum Dresden-Rossendorf

Steinbach, P.; Hoffmann, N.

This poster summarizes the Helmholtz AI local unit for Matter Research installed at HZDR. The poster was presented at the Helmholtz AI Kick-Off Meeting on March 5th, 2020, in Munich, Germany.

Keywords: Helmholtz AI; FWCC; Deep Learning; Machine Learning; Data Science; Kick-Off

  • Open Access Logo Poster (Online presentation)
    Helmholtz AI Kick-Off Meeting, 05.03.2020, München, Deutschland

Permalink: https://www.hzdr.de/publications/Publ-31099
Publ.-Id: 31099


Laboratory study of stationary accretion shock relevant to astrophysical systems

Mabey, P.; Albertazzi, B.; Falize, E.; Michel, T.; Rigon, G.; van Box Som, L.; Pelka, A.; Brack, F.-E.; Kroll, F.; Filippov, E.; Gregori, G.; Kuramitsu, Y.; Lamb, D. Q.; Li, C.; Ozaki, N.; Pikuz, S.; Sakawa, Y.; Tzeferacos, P.; Koenig, M.

Accretion processes play a crucial role in a wide variety of astrophysical systems. Of particular interest are magnetic cataclysmic variables, where, plasma flow is directed along the star’s magnetic field lines onto its poles. A stationary shock is formed, several hundred kilometres above the stellar surface; a distance far too small to be resolved with today’s telescopes. Here, we report the results of an analogous laboratory experiment which recreates this astrophysical system. The dynamics of the laboratory system are strongly influenced by the interplay of material, thermal, magnetic and radiative effects, allowing a steady shock to form at a constant distance from a stationary obstacle. Our results demonstrate that a significant amount of plasma is ejected in the lateral direction; a phenomenon that is under-estimated in typical magnetohydrodynamic simulations and often neglected in astrophysical models. This changes the properties of the post-shock region considerably and has important implications for many astrophysical studies.

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Permalink: https://www.hzdr.de/publications/Publ-31094
Publ.-Id: 31094


Helmholtz AI Consultants at Helmholtz-Zentrum Dresden-Rossendorf

Steinbach, P.

This poster summarizes the dedicated Helmholtz AI consultant team installed at HZDR. The poster was presented at the Helmholtz AI Kick-Off Meeting on March 5th, 2020, in Munich, Germany.

Keywords: Helmholtz AI; consultants; Local Unit; Matter; Kick-Off

  • Open Access Logo Poster
    Helmholtz AI Kickoff, 05.03.2020, München, Deutschland

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Permalink: https://www.hzdr.de/publications/Publ-31093
Publ.-Id: 31093


Directed, elliptic and higher order flow harmonics of protons, deuterons and tritons in Au+Au collisions at sqrt(s_NN)=2.4 GeV

Adamczewski-Musch, J.; Arnold, O.; Behnke, C.; Belounnas, A.; Belyaev, A.; Berger-Chen, J. C.; Blanco, A.; Blume, C.; Böhmer, M.; Bordalo, P.; Chernenko, S.; Chlad, L.; Ciepal, I.; Deveaux, C.; Dreyer, J.; Epple, E.; Fabbietti, L.; Fateev, O.; Filip, P.; Fonte, P.; Franco, C.; Friese, J.; Fröhlich, I.; Galatyuk, T.; Garzón, J. A.; Gernhäuser, R.; Golosov, O.; Golubeva, M.; Greifenhagen, R.; Guber, F.; Gumberidze, M.; Harabasz, S.; Heinz, T.; Hennino, T.; Hlavac, S.; Höhne, C.; Holzmann, R.; Ierusalimov, A.; Ivashkin, A.; Kämpfer, B.; Karavicheva, T.; Kardan, B.; Koenig, I.; Koenig, W.; Kohls, M.; Kolb, B. W.; Korcyl, G.; Kornakov, G.; Kornas, F.; Kotte, R.; Kugler, A.; Kunz, T.; Kurepin, A.; Kurilkin, A.; Kurilkin, P.; Ladygin, V.; Lalik, R.; Lapidus, K.; Lebedev, A.; Lopes, L.; Lorenz, M.; Mahmoud, T.; Maier, L.; Malige, A.; Mamaev, M.; Mangiarotti, A.; Markert, J.; Matulewicz, T.; Maurus, S.; Metag, V.; Michel, J.; Mihaylov, D. M.; Morozov, S.; Müntz, C.; Münzer, R.; Naumann, L.; Nowakowski, K.; Parpottas, Y.; Pechenov, V.; Pechenova, O.; Petukhov, O.; Piasecki, K.; Pietraszko, J.; Przygoda, W.; Pysz, K.; Ramos, S.; Ramstein, B.; Rathod, N.; Reshetin, A.; Rodriguez-Ramos, P.; Rosier, P.; Rost, A.; Rustamov, A.; Sadovsky, A.; Salabura, P.; Scheib, T.; Schuldes, H.; Schwab, E.; Scozzi, F.; Seck, F.; Sellheim, P.; Selyuzhenkov, I.; Siebenson, J.; Silva, L.; Singh, U.; Smyrski, J.; Sobolev, Y. G.; Spataro, S.; Spies, S.; Ströbele, H.; Stroth, J.; Sturm, C.; Svoboda, O.; Szala, M.; Tlusty, P.; Traxler, M.; Tsertos, H.; Usenko, E.; Wagner, V.; Wendisch, C.; Wiebusch, M. G.; Wirth, J.; Wójcik, D.; Zanevsky, Y.; Zumbruch, P.

Flow coefficients vn of the orders n=1−6 are measured with the High-Acceptance DiElectron Spectrometer (HADES) at GSI for protons, deuterons and tritons as a function of centrality, transverse momentum and rapidity in Au+Au collisions at sqrt(s_NN)=2.4 GeV. Combining the information from the flow coefficients of all orders allows to construct for the first time, at collision energies of a few GeV, a complete, multi-differential picture of the emission pattern of these particles. The ratio v4/v22 at mid-rapidity is found to be remarkably close to the value 0.5, as might be indicative for an ideal fluid scenario.

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Permalink: https://www.hzdr.de/publications/Publ-31092
Publ.-Id: 31092


Corrigendum to “Controls on strath terrace formation and evolution: The lower Guadiana River, Pulo do Lobo, Portugal”

Ortega-Becerril, J. A.; Garzón, G.; Tejero, R.; Meriaux, A.-S.; Delunel, R.; Merchel, S.; Rugel, G.

The authors regret publishing the original article while omitting four authors. The correct author list and affiliations have now been corrected.
We would also like to make the clarifications and corrections listed below on the cosmogenic radionuclide (CRN) analysis.
1) All ¹⁰Be samples were collected in 2010 and prepared at the Newcastle Cosmogenic Isotope Laboratory. Accelerator mass spectrometry (AMS) of ¹⁰Be was performed in 2011 at the DREAMS-facility at the Helmholtz-ZentrumDresden-Rossendorf (HZDR) (Akhmadaliev et al., 2013).
2) All the ¹⁰Be model ages were calculated similarly to Mériaux et al. (2012). Spallation and muon production rate schemes are compatible with the CRONUS-Earth calculator v2.2 using the mid-latitude attenuation length of Farber et al. (2008). Ζero erosion model ages were calculated similarly than the Stone/Lal scaling scheme of Balco et al. (2008) with a constant production rate “St” for ¹⁰Be of 4.49 ± 0.39 atoms/g·year instead of the updated 4.01 ± 0.32 atoms/g·year for that scheme by Phillips et al. (2016). The “St” model ages are corrected for the production rate update. Thickness corrections assume a density of ρ = 2.65 g/cm³ for each sample.
The topographic shielding is derived from topographic data collected in the field. The propagated analytical uncertainties include
error blank, carrier, counting statistics and the uncertainty of the standard-like material SMD-Be-12 (Akhmadaliev et al., 2013). The propagated uncertainties include statistical uncertainties from the AMS, 8% uncertainty on the production rate, 0.87% for the decay constants of ¹⁰Be (Korschinek et al., 2010), as well as uncertainty of 5% on the density and 2.25% on the attenuation length of 177 ± 4 g/cm² (Farber et al., 2008). The ages are given in ka. Table 2 has been corrected and completed with the time-dependent model ages calculated using the “LSDn” scaling model (Lifton et al., 2014).
These “LSDn” model ages integrate the variation of the magnetic field over time together with the non-dipole field components and up-to-date spallation and muon scaling schemes with elevation, latitude and longitude, and production rate of 3.92 ± 0.31 atoms/g·year for this LSDn scaling (see Borchers et al., 2016, Marrero et al., 2016 and Phillips et al., 2016 for details). In both cases, all the CRN model ages are calculated assuming no erosion, therefore all these models are minimum ages for that of the strath terraces.
The authors would like to apologise for any inconvenience caused.

Keywords: AMS; geomorphology

Permalink: https://www.hzdr.de/publications/Publ-31090
Publ.-Id: 31090


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